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글리시리진

글리시리진
글리시리진 구조식 이미지
카스 번호:
1405-86-3
한글명:
글리시리진
동의어(한글):
글리시리진;글리시리직애씨드
상품명:
Glycyrrhizic acid
동의어(영문):
glycyron;Potenlini;DerMacrin;liquorice;NSC 167409;NSC 234419;GLYCYRRHIZIN;Glycyrrhizic;Glycyrrhitin;Glycyrrhizine
CBNumber:
CB0482721
분자식:
C42H62O16
포뮬러 무게:
822.94
MOL 파일:
1405-86-3.mol

글리시리진 속성

녹는점
220°C (rough estimate)
끓는 점
681.01°C (rough estimate)
알파
D17 +46.2° (c = 1.5 in alc)
밀도
1.1442 (rough estimate)
굴절률
61 ° (C=1.5, EtOH)
저장 조건
Inert atmosphere,2-8°C
산도 계수 (pKa)
2.76±0.70(Predicted)
Merck
14,4505
InChIKey
BXFBITNYMHAJGT-KYXJNIQISA-N
CAS 데이터베이스
1405-86-3
EPA
Glycyrrhizin (1405-86-3)

안전

안전지침서 22-24/25
WGK 독일 3
RTECS 번호 MD2025000
HS 번호 29389090
유해 물질 데이터 1405-86-3(Hazardous Substances Data)
기존화학 물질 KE-18076

글리시리진 C화학적 특성, 용도, 생산

화학적 성질

White to off-white powder

화학적 성질

Glycyrrhizin, also known as glycyrrhizic acid, is a glycoside isolated from the roots of licorice, Glycyrrhiza glabra L. For improved water solubility, an ammoniated salt is commonly used. This can be in the form of either ammonium glycyrrhizinate or monoammonium glycyrrhizinate.

용도

Glycyrrhizin is a flavorant and foaming agent derived from the separation of flavonoids found in the whole licorice extract from the licorice root glycyrrhiza glabra. It is 50–100 times as sweet as sugar, is soluble in water, and has a licorice taste. It has good heat stability but prolonged heating can result in some degradation. It is stable within ph 4–9; below ph 4 there could be precipitation. It has foaming and emulsifying properties in water, being used in cocktail mixes and soft drinks. It is used as a flavorant in bacon and imitation whipped products. It is synergistic with sugar, the sweetness being amplified to 100 times that of cane sugar alone. It is used as a sweetener in sugar-free chewing gum and low-fat sugar-free frozen desserts. It is also termed ammoniated glycyrrhizin. Monoammonium glycyrrhizinate is obtained by additional refinement.

용도

glycyrrhizic acid is a hydrolyzed glycyrrhizin. It is credited with antiinflammatory and anti-allergenic properties. Studies comparing glycyrrhizin with hydrocortisone found glycyrrhizin to be somewhat milder but longer lasting in effectiveness. once the application of hydrocortisone is suspended, the symptoms return. This does not appear to be the case with glycyrrhizin. It does not have side effects and is chemically stable so it can be safely used on a continuing basis.

용도

11beta-hydroxysteroid dehydrogenase inhibitor, antiinflammatory, expectorant, antihaemorrhagic, anti-HIV

용도

Glycyrrhizic acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.

정의

ChEBI: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence and changes in the metabolism of phosphorus, When heated to decomposition it emits acrid smoke and irritating fumes.

글리시리진 준비 용품 및 원자재

원자재

준비 용품


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