3-클로로페록시벤조산
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3-클로로페록시벤조산 속성
- 녹는점
- 69-71 °C(lit.)
- 끓는 점
- 244.67°C (rough estimate)
- 밀도
- 0.56
- 증기압
- 0.373Pa at 25℃
- 굴절률
- 1.4580 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올(약간 용해됨)
- 용해도
- 클로로포름(약간), 에틸아세테이트(약간), 메탄올(약간)에 용해됨
- 산도 계수 (pKa)
- 7.57 (in water @ 25 °C)
- 물리적 상태
- 촉촉한 파우더
- 색상
- 하얀색
- 수소이온지수(pH)
- 4.5@25 °C (saturated aq. sol)
- 냄새
- 약간 자극적인 냄새
- 수용성
- 불용성
- 분해온도
- >88 °C
- BRN
- 608317
- 안정성
- 강한 산화제 - 가연성 물질과 접촉하면 화재가 발생할 수 있습니다. 충격이나 열에 민감할 수 있습니다. 유기 물질과 호환되지 않으며 강력한 환원제입니다.
- InChIKey
- NHQDETIJWKXCTC-UHFFFAOYSA-N
- LogP
- 1.03 at 25℃
- CAS 데이터베이스
- 937-14-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | O,Xi,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 5-8-36/37/38-43-7-34-22 | ||
| 안전지침서 | 17-26-36/37-45-36/37/39-3/7-14-27-7/9 | ||
| 유엔번호(UN No.) | UN 3106 5.2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | SD9470000 | ||
| F 고인화성물질 | 4.4 | ||
| TSCA | Yes | ||
| 위험 등급 | 5.2 | ||
| 포장분류 | II | ||
| HS 번호 | 29163990 | ||
| 기존화학 물질 | KE-05526 |
3-클로로페록시벤조산 C화학적 특성, 용도, 생산
물성
분자의 화학적 구조는 원자의 배열과 각 해당 원자들 간의 화학결합으로 결정된다. 3-클로로페록시벤조산 분자는 5 개의 수소 원자, 7 개의 탄소 원자, 3 개의 산소 원자 그리고 1 개의 염소 원자로 구성되어 총 16 개의 원자로 형성된다. 3-클로로페록시벤조산 분자에는 총 16 개의 화학결합이 있으며, 이는 11 개의 비수소결합, 7 개의 다중결합, 2 개의 단일결합, 1 개의 이중결합, 6 개의 방향족결합, 1 개의 6원자 고리 그리고 1 개의 수산기로 구성되어 있다. [네이버 지식백과] 3-클로로페록시벤조산 [3-Chloroperoxybenzoic acid] (화학물질 구조사전, Mol-Instincts 화학물질 데이터베이스)화학적 성질
White moist powder용도
3-Chloroperoxybenzoic acid is a strong oxidizing agent used in the oxidation reactions such as aldehydes and ketones to esters (Bayer-Villiger-Oxidation), olefines to epoxides, sulfides to sulfoxides and sulfones, and amines to nitroalkanes, N-oxides.화학 반응
3-Chloroperoxybenzoic acid (MCPBA) is one of the most popular oxidation reagent in organic synthesis, because of its outstanding performance in terms of:reactivity, combined with reducing the number of reaction steps in classical synthetic routes,
regio- and stereoselectivity,
protection of functional groups mostly not required,
high purity and yields.
Its literature covers a huge area of different syntheses and below reaction equations just can be a brief overview of its interesting applications:
일반 설명
3-Chloroperoxybenzoic acid is sensitive to heat. Storage of 3-Chloroperoxybenzoic acid must be done so with stringent temperature control measures. It's explosion hazard is also mitigated by mixing the peroxide in a solvent slurry.반응 프로필
May explode from heat, shock, friction or contamination. May ignite combustibles (wood, paper, oil, clothing, etc.). May be ignited by heat, sparks or flames.Purification Methods
Recrystallise MCPBA from CH2Cl2 [Traylor & Mikztal J Am Chem Soc 109 2770 1987]. Peracid of 99+% purity can be obtained by washing commercial 85% material with phosphate buffer pH 7.5 and drying the residue under reduced pressure. Alternatively the peracid can be freed from m-chlorobenzoic acid by dissolving 50g/L of *benzene and washing with an aqueous solution buffered at pH 7.4 (NaH2PO4/NaOH) (5 x 100mL). The organic layer is dried over MgSO4 and carefully evaporated under vacuum. Necessary care should be taken in case of EXPLOSION. The solid is recrystallised twice from CH2Cl2/Et2O and stored at 0o in a plastic container as glass catalyses the decomposition of the peracid. The acid is assayed iodometrically. [Schwartz & Blumbrgs J Org Chem 29 1976 1964, Bortolini et al. J Org Chem 52 5093 1987, McDonald et al. Org Synth Coll Vol VI 276 1988, Beilstein 9 IV 972.]3-클로로페록시벤조산 준비 용품 및 원자재
원자재
준비 용품
5-Bromo-2-hydroxymethylpyridine
3-(TERT-BUTOXYCARBONYLAMINO-METHYL)-PYRIDINE-2-CARBOXYLIC ACID
6-BROMO-1H-PYRROLO[2,3-B]PYRIDINE
5-BROMO-2-METHYLPYRIDINE N-OXIDE
LORACARBEF (200 MG)
4-IODO-7-AZAINDOLE
에폭시헥산(1,2-)
4-(CHLOROSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE
3-이소크로마논
4-(METHYLSULFINYL)PHENOL
3,5-DIMETHYLPYRIDIN-4-AMINE
8-히드록시-2-퀴놀린카보니트릴
4,5-DICHLORO-2-METHYLPYRIDINE
1H-Pyrrolo[2,3-b]pyridine, 4-nitro-, 7-oxide
3-AMINOMETHYL-PYRIDINE-2-CARBOXYLIC ACID
4-[(TERT-BUTOXYCARBONYLAMINO)METHYL]-2-CYANOPYRIDINE
4-Bromo-7-azaindole
Tacalcitol
헥사하이드로니트로벤젠
4-Chloro-7-azaindole
7-OXIDE-7-AZAINDOLE
4-(BOC-AMINOMETHYL)PYRIDINE-2-CARBOXYLIC ACID
4-Chloro-2-(methylsulfonyl)pyrimidine
5-BROMO-4-CHLORO-2-METHANESULFONYL-PYRIMIDINE
4-FLUORO-2,1,3-BENZOXADIAZOLE
2-(2,3-DIHYDRO-1-BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ACETONITRILE
METHYL(2R,3S)-2,2-DIMETHYL-3-(2-OXOPROPYL)-CYCLOPROPANEACETATE
1,7-DIDEAZAADENINE
판토프라졸
오메프라졸
Cyclopentene oxide
3-NITROSOBENZAMIDE
5-Bromopyridine-2-carbaldehyde
6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
1,4-OXATHIANE SULFOXIMINE
1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO-
2,5-Dichloropyridine
S-METHYL-S-(2-METHYLPYRAZINYL) SULFOXIMINE
에폭시(1,2-)-9-데센
1-PROPANESULPHONYLACETONITRILE
3-클로로페록시벤조산 공급 업체
글로벌( 400)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 13854 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Changzhou waston chemical technology Co.,Ltd | +86-051985861892 +8618112881323 |
info@wastonchem.com | China | 237 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2967 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |