리놀레인산

리놀레인산
리놀레인산 구조식 이미지
카스 번호:
60-33-3
한글명:
리놀레인산
동의어(한글):
리놀레산;리놀레인산;리놀레익애씨드
상품명:
Linoleic acid
동의어(영문):
Linoleic;9,12-OCTADECADIENOIC ACID;LINOLEATE;(9Z,12Z)-Octadeca-9,12-dienoic acid;LINOLIC ACID;(Z,Z)-9,12-Octadecadienoic acid;CASTOR OIL FATTY ACID;9,12-Linoleic acid;Linoleic Acid (peroxide free);9,12-octadecadienoic
CBNumber:
CB5764024
분자식:
C18H32O2
포뮬러 무게:
280.45
MOL 파일:
60-33-3.mol
MSDS 파일:
SDS

리놀레인산 속성

녹는점
-5 °C (lit.)
끓는 점
229-230 °C/16 mmHg (lit.)
밀도
0.902 g/mL at 25 °C (lit.)
FEMA
3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
굴절률
n20/D 1.466(lit.)
인화점
>230 °F
저장 조건
Store below +30°C.
용해도
NaOH: 용해성1M
산도 계수 (pKa)
4.77(at 25℃)
물리적 상태
액체
색상
맑은 노란색
냄새
약간의 기름 냄새
수용성
불용성
어는점
-5℃
감도
Air Sensitive
최대 파장(λmax)
270nm(H2O)(lit.)
JECFA Number
332
Merck
14,5505
BRN
1727101
Dielectric constant
2.6(0℃)
안정성
안정적이지만 공기와 빛에 민감합니다. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
InChIKey
OYHQOLUKZRVURQ-KQHSAVHASA-N
LogP
7.050
CAS 데이터베이스
60-33-3(CAS DataBase Reference)
NIST
9,12-Octadecadienoic acid (Z,Z)-(60-33-3)
EPA
Linoleic acid (60-33-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36-36/37/38
안전지침서 26-24/25-36-37/39
유엔번호(UN No.) UN1170 - class 3 - PG 2 - Ethanol
WGK 독일 1
RTECS 번호 RF9990000
F 고인화성물질 8-10-23
TSCA Yes
HS 번호 29161500
유해 물질 데이터 60-33-3(Hazardous Substances Data)
독성 LD50 oral in mouse: > 50gm/kg
기존화학 물질 KE-26285
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H225 고인화성 액체 및 증기 인화성 액체 구분 2 위험 GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
예방조치문구:
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P370+P378 화재 시 불을 끄기 위해 (Section 5. 폭발, 화재시 대처방법의 적절한 소화제)을(를) 사용하시오.
P403+P235 환기가 잘 되는 곳에 보관하고 저온으로 유지하시오.
NFPA 704
1
0 1

리놀레인산 MSDS


cis-9,cis-12-Octadecadienoic acid

리놀레인산 C화학적 특성, 용도, 생산

물성

옅은 노란색 레드 유성 액체.

개요

Linoleic acid is an essential ω-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 μM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.

화학적 성질

Linoleic acid occurs as a colorless to light-yellow-colored oil.

용도

linoleic acid (vitamin F) is also known as omega-6. An emulsifier, it is also cleansing, emollient, and skin conditioning. Some formulations incorporate it as a surfactant. Linoleic acid prevents dryness and roughness. A deficiency of linoleic acid in the skin is associated with symptoms similar to those characterizing eczema, psoriasis, and a generally poor skin condition. In numerous laboratory studies where a linoleic acid deficiency was induced, a topical application of linoleic acid in its free or esterified form quickly reversed this condition. In addition, there is some evidence in laboratory tests that linoleic acid may inhibit melanin production by decreasing tyrosinase activity and suppressing melanin polymer formation within melanosomes. Linoleic acid is an essential fatty acid found in a variety of plant oils, including soybean and sunflower.

정의

linoleic acid: A liquid polyunsaturatedfatty acid with two doublebonds, CH3(CH2)4CH:CHCH2-CH:CH(CH2)7COOH.Linoleic acid isabundant in plant fats and oils,e.g.linseed oil, groundnut oil,and soyabeanoil.It is an essential fatty acid.

생산 방법

Linoleic acid is obtained by extraction from various vegetable oils such as safflower oil.

일반 설명

Colorless to straw colored liquid. A polyunsaturated fatty acid essential to human diet.

공기와 물의 반응

Sensitive to air and light. . Oxidizes across carbon double bonds

반응 프로필

Linoleic acid reacts to neutralize bases. May react vigorously with oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.

화재위험

Flash point data for Linoleic acid are not available. Linoleic acid is probably combustible.

Pharmaceutical Applications

Linoleic acid is used in topical transdermal formulations, in oral formulations as an absorption enhancer, and in topical cosmetic formulations as an emulsifying agent, and in aqueous microemulsions.It is also used in parenteral emulsions for total parenteral nutrition and in nonprescription oral dietary supplements.

Safety

Linoleic acid is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a nontoxic material. On exposure to the eyes, skin, and mucous membranes, linoleic acid can cause mild irritation.

저장

Linoleic acid is sensitive to air, light, moisture, and heat. It should be stored in a tightly sealed container under an inert atmosphere and refrigerated.

비 호환성

Linoleic acid is incompatible with bases, strong oxidizing agents, and reducing agents.

Regulatory Status

GRAS listed. Approved for use in foods in Europe and the USA.

리놀레인산 준비 용품 및 원자재

원자재

준비 용품


리놀레인산 공급 업체

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