4-사이클로레조시놀
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4-사이클로레조시놀 속성
- 녹는점
- 106-108 °C (lit.)
- 끓는 점
- 147 °C/18 mmHg (lit.)
- 밀도
- 1.2558 (rough estimate)
- 증기압
- 0.16Pa at 25℃
- 굴절률
- 1.4620 (estimate)
- 인화점
- 146-148°C/18mm
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- >1000g/L
- 산도 계수 (pKa)
- 8.28±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 베이지색
- 수소이온지수(pH)
- 3.8 (10g/l, H2O, 30℃)
- 수용성
- 녹는
- BRN
- 2042864
- 안정성
- 안정적인. 산 염화물, 산 무수물, 산화제와 호환되지 않습니다.
- LogP
- 0.895 at 25℃
- CAS 데이터베이스
- 95-88-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22-36/37/38-22 | ||
안전지침서 | 26-36-22 | ||
WGK 독일 | 3 | ||
RTECS 번호 | VH0450000 | ||
TSCA | Yes | ||
HS 번호 | 29081000 | ||
기존화학 물질 | KE-05529 |
4-사이클로레조시놀 C화학적 특성, 용도, 생산
화학적 성질
4-Chlororesorcinol is a colorless crystals or off-white to light brown powder. The melting point is 89°C (106.5-107.5°C), the boiling point is 259°C, 147°C (2.4kPa). Soluble in water, alcohol, ether, benzene and carbon disulfide. Can sublimate. It reacts with ferric chloride to generate blue-purple.용도
4-Chlororesorcinol, can be used as hair dye formulation. It can also be used in the synthesis of series of six coumarin compounds carrying halogen and trifluoromethyl, having antifungal activities.주요 응용
In cosmetics and personal care products, 4-Chlororesorcinol is used in the formulation of hair dyes, colors and tints.4-Chlororesorcinol is used in permanent hair coloring systems where color is produced inside the hair fiber. This is accomplished through careful formulation of the product so that the ingredients interact in a highly controlled process.
제조 방법
4-Chlororesorcinol is synthesized by reacting resorcinol with dichlorosulfuryl. Resorcinol and diethyl ether were mixed, heated to reflux with stirring, and dichlorosulfuryl was slowly added dropwise. The temperature was then raised to 60°C for 1 h. After recovery of ether, atmospheric distillation is carried out, the distillate is subjected to vacuum distillation again, and the 131°C (0.8-0.93kPa) or 160-164°C (4.0kPa) fractions are collected to obtain the finished 4-chlororesorcinol.Safety
4-chlororesorcinol is classified as a toxic substance and exposure to high concentration of 4-chlororesorcinol could cause several health issues including, skin irritation, serious eye irritation, and other hazards.The safety of 4-Chlororesorcinol has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that 4-Chlororesorcinol was safe in hair dye formulations.
The CIR Expert Panel concluded that the scientific data suggested that 4-Chlororesorcinol can be safely used in hair dye products. Subchronic dermal exposure to a hair dye product containing 2% 4-Chlororesorcinol produced no evidence of compound-induced toxicity. At the same concentration, no development effects, no evidence of reproductive toxicity, and no carcinogenic effects were seen following dermal exposure. Likewise, 4-Chlororesorcinol was not mutagenic in either a micronucleus or in bacteria, nor did it induce aneuploidy in fungus cells. A 2.5% solution was not a dermal irritant or an ocular irritant.
Purification Methods
Crystallise it from boiling CCl4 (10g/L, charcoal) and dry it in air. [Beilstein 6 II 818.] IRRITANT.4-사이클로레조시놀 준비 용품 및 원자재
원자재
레조시놀
염화설퍼릴
Urea, N,N-dichloro-
3-클로로-2,6-디메톡시벤조산,97
3-클로로-2,6-디히드록시벤조산
2,4-디히드록시-5-클로로벤조산
4-Chloro-1,3-benzenediamine
3-아세톡시-2-시클로헥센-1-원
2,4-디클로로페녹시에타노익 엑시드
2-Chlororesorcinol
준비 용품
4-사이클로레조시놀 공급 업체
글로벌( 435)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 |
sales@qinmuchem.com | China | 1009 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2990 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14335 | 58 |
4-사이클로레조시놀 관련 검색:
에피클로로하이드린 4-t-부틸카테콜 2-t-부틸하이드로퀴논 하이드로퀴논 포름알데히드-1,3-벤젠디올 중합체 카테콜 레조시놀 클로로벤젠 클로로디플루오르메탄 클로로아세트산 2'',7''-디클로로플르오르엑세인 오르시놀
Solvent Red 43
4,6-DICHLORORESORCINOL
3-BROMO-5-CHLORO-2,6-DIMETHOXYBENZOIC ACID
2',7'-DICHLOROFLUORESCIN DIACETATE
N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide
4-AMINO-6-CHLORORESORCINOL DIMETHYL ETHER