ChemicalBook
Chinese English Japanese Germany Korea

8-하이드록시퀴놀린

8-하이드록시퀴놀린
8-하이드록시퀴놀린 구조식 이미지
카스 번호:
148-24-3
한글명:
8-하이드록시퀴놀린
동의어(한글):
8-히드록시퀴놀린;퀴노페놀;페노피리딘;8-퀴놀리놀;8-하이드록시퀴놀린;바이오퀸;옥시-벤조피리딘;옥시퀴놀린;옥신;하이드록시벤조피리딘;하이드록시-8-퀴놀린
상품명:
8-Hydroxyquinoline
동의어(영문):
OQ;8-OQ;Oxin;Tumex;OXINE;8-Oxine;BIOQUIN;NSC 2039;8-Quinol;Fennosan
CBNumber:
CB8435187
분자식:
C9H7NO
포뮬러 무게:
145.16
MOL 파일:
148-24-3.mol

8-하이드록시퀴놀린 속성

녹는점
70-73 °C(lit.)
끓는 점
267 °C752 mm Hg(lit.)
밀도
1.0340
굴절률
1.4500 (estimate)
인화점
267°C
저장 조건
Store at RT.
용해도
0.56g/l
산도 계수 (pKa)
5.017(at 20℃)
물리적 상태
Liquid
색상
White to pale yellow or light beige
수용성
INSOLUBLE
감도
Light Sensitive
Merck
14,4843
BRN
114512
InChIKey
MCJGNVYPOGVAJF-UHFFFAOYSA-N
CAS 데이터베이스
148-24-3(CAS DataBase Reference)
NIST
8-Quinolinol(148-24-3)
EPA
8-Quinolinol (148-24-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,Xi
위험 카페고리 넘버 22-68-36/37/38
안전지침서 45-36/37/39-26-36
유엔번호(UN No.) 2811
WGK 독일 3
RTECS 번호 VC4200000
위험 참고 사항 Harmful/Irritant
TSCA Yes
위험 등급 9
포장분류 III
HS 번호 29334990
유해 물질 데이터 148-24-3(Hazardous Substances Data)
독성 LD50 orally in Rabbit: 1200 mg/kg
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H341 유전적인 결함을 일으킬 것으로 의심됨 (노출되어도 생식세포 유전독성을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 생식세포 변이원성 물질 구분 2 경고 P201,P202, P281, P308+P313, P405,P501
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
P405 밀봉하여 저장하시오.

8-하이드록시퀴놀린 MSDS


8-Quinolinol

8-하이드록시퀴놀린 C화학적 특성, 용도, 생산

화학적 성질

Cream-colored crystals

용도

antiinfectant, complexing agent

정의

ChEBI: A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.

상표명

Aci-jel;Benzease;Chinosol;Cp-cap;Dermacid;Dermoplast;Fennosan h 30;Heriat;Hydroxybenoxopyridine;Medicone derma-hc;Oxykin;Oxyquinoline-rhp;Pedivol;Phenopyridine;Preconsol;Quinoderm;Quinoped;Quinophenol;Recta medicone-hc;Semori;Serohinol;Serorhinol;Superol;Trimo-san;Triva douch powder;Triva jel.

World Health Organization (WHO)

Halogenated hydroxyquinoline is structurally related to clioquinol. See WHO comment for clioquinol. (Reference: (WHODI) WHO Drug Information, 77.1, 9, 1977)

일반 설명

White to off-white or faintly yellow crystalline powder. Phenolic odor.

공기와 물의 반응

Insoluble in water.

반응 프로필

8-Hydroxyquinoline darkens on exposure to light. 8-Hydroxyquinoline readily forms stable metal chelates. 8-Hydroxyquinoline is incompatible with strong oxidizers. 8-Hydroxyquinoline is also incompatible with many metal ions.

위험도

Toxic by ingestion. Questionable carcinogen.

화재위험

Flash point data for 8-Hydroxyquinoline are not available; however, 8-Hydroxyquinoline is probably combustible.

Clinical Use

Oxine, quinophenol, or oxyquinoline is the parent compoundfrom which the antiprotozoal oxyquinolines havebeen derived. The antibacterial and antifungal properties of oxine and its derivatives, which are believed to result fromthe ability to chelate metal ions, are well known. Aqueoussolutions of acid salts of oxine, particularly the sulfate(Chinosol, Quinosol), in concentrations of 1:3,000 to1:1,000, have been used as topical antiseptics. The substitutionof an iodine atom at the 7-position of 8-hydroxyquinolinesyields compounds with broad-spectrum amebicidalproperties.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Experimental reproductive effects. A central nervous system stimulant. Human mutation data reported. Combustible when exposed to heat or flame. When heated to decomposition it emits hghly toxic fumes of NOx.

Purification Methods

Crystallise oxine from hot EtOH, acetone, pet ether (b 60-80o) or water. Crude oxine can be purified by precipitation of copper oxinate, followed by liberation of free oxine with H2S or by steam distillation after acidification with H2SO4. Store it in the dark. It forms complexes with many metals. [Manske et al. Can J Research 27F 359 1949, Phillips Chem Rev 56 271 1956, Beilstein 21 III/IV 1135, 21/3 V 252.]

8-하이드록시퀴놀린 준비 용품 및 원자재

원자재

준비 용품


8-하이드록시퀴놀린 공급 업체

글로벌( 594)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23048 58
Zhengzhou Yuanli Biological Technology Co., Ltd
0086-371-67897895
info@zzyuanli.cn CHINA 136 58
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1892 55
Tangshan Moneide Trading Co., Ltd.
86-315-8309571 15633399667
sales@moneidechem.com CHINA 530 58
Springchem New Material Technology Co.,Limited
86-21-51752791
86-21-51752789 info@spring-chem.com China 1765 57
Capot Chemical Co.,Ltd.
+86-571-85586718
+86-571-85864795 sales@capotchem.com China 19920 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21806 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile
+86-571-56059825 fandachem@gmail.com CHINA 3013 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24687 60

8-하이드록시퀴놀린 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved