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Flucloxacillin

Flucloxacillin 구조식 이미지
카스 번호:
5250-39-5
상품명:
Flucloxacillin
동의어(영문):
Flopen;Flucil;Culpen;FK 900;Flupen;Penplus;Floxapen;Abboflox;BRL 2039;Staphylex
CBNumber:
CB8690991
분자식:
C19H17ClFN3O5S
포뮬러 무게:
453.87
MOL 파일:
5250-39-5.mol

Flucloxacillin 속성

산도 계수 (pKa)
pKa 2.7 (Uncertain)
CAS 데이터베이스
5250-39-5(CAS DataBase Reference)

안전

Flucloxacillin C화학적 특성, 용도, 생산

용도

Antibacterial.

정의

ChEBI: A penicillin compound having a 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain.

Antimicrobial activity

There is complete cross-resistance with other penicillinase-stable penicillins.

Pharmacokinetics

Oral absorption: c. 80%
Cmax 250 mg (oral): 11 mg/L after 0.5–1 h
Plasma half-life: 2 h
Plasma protein binding: 95%
Absorption and distribution
It is well absorbed after oral administration and penetrates rapidly into extravascular exudates. Its high protein binding limits its diffusion, notably into the normal CSF.
Metabolism and excretion
Flucloxacillin is partly metabolized in the liver and about 10% of the plasma concentration is made up of metabolites. It is more slowly eliminated than cloxacillin. Some appears in the bile but about 50–80% of an oral dose is recovered from the urine, about 20% as metabolites.

Clinical Use

Uses are those of group 3 penicillins.

부작용

In patients treated by intravenous infusion, about 5% developed phlebitis by the first and 15% by the second day, after which the proportion rose dramatically. Side effects are otherwise those common to penicillins.

Flucloxacillin 준비 용품 및 원자재

원자재

준비 용품


Flucloxacillin 공급 업체

글로벌( 35)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202,021-54308259
+86-21-64545202 info@hanhonggroup.com China 43260 64
XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
86-712-2580625 QQ:1791901229 farchem@qq.com China 9072 52
Shanghai G&K Biomedical Scientific Inc. +86-21-34502253 13391330186
+86-21-23027826 info@gksci.com China 133 52
China Langchem Inc. 0086-21-58956006,021-38701807;021-58950017
0086-21-58956100 sales@langchem.com China 7836 57
S.Z. PhyStandard Bio-Tech. Co., Ltd. 18165736994,4000505016
+86 755 28094224 marketing@phystandard.com China 5621 50
Beijing HuaMeiHuLiBiological Chemical 010-56205725;010-86181995
010-65763397 waley188@sohu.com China 12341 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-58378339;025-57798810
025-57019371 sales@sunlidabio.com China 3818 55
Hubei XinyuanShun Chemical Co., Ltd. 13971561712 / 13995564702 / 027-50664929
027-50664927 hbeixys2001@163.com China 3130 55

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