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Emedastine

Emedastine 구조식 이미지

카스 번호:: 87233-61-2

상품명:: Emedastine

동의어(영문):: EMEDASTINE;Emedastine impurity F;Emedastine Impurity 14;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole;1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole;1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole;1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole;1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole;allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis

CBNumber:: CB8728076

분자식:: C17H26N4O

포뮬러 무게:: 302.41

MOL 파일:: 87233-61-2.mol

속성

안전

용도

공급 업체 82

Emedastine 속성

끓는 점: 446.6±55.0 °C(Predicted)

밀도: 1.15±0.1 g/cm3(Predicted)

저장 조건: 2-8°C

용해도: DMSO: 125 mg/mL (413.35 mM); Ethanol: 100 mg/mL (330.68 mM)

산도 계수 (pKa): 8.86±0.10(Predicted)

CAS 데이터베이스: 87233-61-2(CAS DataBase Reference)

안전

Emedastine C화학적 특성, 용도, 생산

용도

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

정의

ChEBI: 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the ifumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

Clinical Use

Emedastine also is a newer antihistamine used topically in the eye for conjunctivitis. It has very high H1 receptor selectivity characteristics, and it is structurally related to the benzimidazoles, such as astemizole. Inhibition of mast cell release of inflammatory mediators has been noted.

Emedastine 준비 용품 및 원자재

원자재

N-(2-ETHOXY-ETHYL)-BENZENE-1,2-DIAMINE (2-ETHOXY-ETHYL)-(2-NITRO-PHENYL)-AMINE EMEDASTINE IMPURITY E 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE 1H-BENZIMIDAZOLE,2-CHLORO-1-(2-ETHOXYETHYL) 1-Boc-hexahydro-1,4-diazepine 메틸호모피페라진 2-Chlorobenzimidazole 아닐린 포르말린 O-클로로니트로벤젠

준비 용품

Emedastine 공급 업체

글로벌( 82)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58

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