Diuretics Drugs

Diuretic drugs are drugs that can stimulate the kidney to secret the electrolyte and water lagged in the body, and thereby increasing the amount of urine. This kind of drug can treat the edema, pulmonary edema and brain edema caused by heart, liver, kidney and other diseases. Some drugs also have antihypertensive effects, for example, thiazide diuretics have been recommended being as an important class of antihypertensive drugs. According the difference of action site and mechanism of action, diuretics can be divided into thiazide diuretics; loop diuretics; potassium –sparing diuretics; carbonic anhydrase inhibitors; osmotic diuretics, and uricosuric diuretics, six major categories. The effectiveness of various types of diuretics is related to action site, drug dose, renal blood flow, circulating blood volume and plasma electrolyte levels (see the relevant entries). Clinicians should appropriately apply it based on drug characteristics and the specific circumstances. It has been already known that the above-mentioned various types of diuretics are known as natriuretic diuretic drugs with the amount of excretion being in line with the diuretic effect. They can all promote potassium excretion except potassium-sparing diuretics, which is easy to cause hypokalemia. In addition, the existing diuretics can promote the release of renin, resulting in the increase of the formation of angiotensin and aldosterone, leading to elevated blood lipids, blood sugar and induced gout. Therefore, the application of diuretics should pay attention to prevention and treatment.
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Structure Chemical Name CAS MF
Tolterodine Tolterodine 124937-51-5 C22H31NO
Theobromine Theobromine 83-67-0 C7H8N4O2
Hydrochlorothiazide Hydrochlorothiazide 58-93-5 C7H8ClN3O4S2
Azosemide Azosemide 27589-33-9 C12H11ClN6O2S2
Phenazopyridine hydrochloride Phenazopyridine hydrochloride 136-40-3 C11H11N5.ClH
Furosemide Furosemide 54-31-9 C12H11ClN2O5S
Spironolactone Spironolactone 52-01-7 C24H32O4S
SodiumEtacrynate SodiumEtacrynate C13H11Cl2NaO4
Acetazolamide Acetazolamide 59-66-5 C4H6N4O3S2
Triamterene Triamterene 396-01-0 C12H11N7
Flavoxate hydrochloride Flavoxate hydrochloride 3717-88-2 C24H26ClNO4
Trichlormethiazide Trichlormethiazide 133-67-5 C8H8Cl3N3O4S2
Chlorothiazide Chlorothiazide 58-94-6 C7H6ClN3O4S2
Bumetanide Bumetanide 28395-03-1 C17H20N2O5S
DICHLORPHENAMIDE DICHLORPHENAMIDE 120-97-8 C6H6Cl2N2O4S2
Ethacrynic acid Ethacrynic acid 58-54-8 C13H12Cl2O4
Amiloride hydrochloride Amiloride hydrochloride 2016-88-8 C6H8ClN7O.ClH
Metolazone Metolazone 17560-51-9 C16H16ClN3O3S
Cyclopenthiazide Cyclopenthiazide 742-20-1 C13H18ClN3O4S2
FLAVOXATE FLAVOXATE 15301-69-6 C24H25NO4
QUINETHAZONE (1.5 G) QUINETHAZONE (1.5 G) 73-49-4 C10H12ClN3O3S
BENDROFLUMETHIAZIDE BENDROFLUMETHIAZIDE 73-48-3 C15H14F3N3O4S2
POLYTHIAZIDE (200 MG) POLYTHIAZIDE (200 MG) 346-18-9 C11H13ClF3N3O4S3
CLOFENAMIDE CLOFENAMIDE 671-95-4 C6H7ClN2O4S2
MERSALYL ACID MERSALYL ACID 486-67-9 C13H17HgNO6
6-ETHOXY-2-BENZOTHIAZOLESULFONAMIDE 6-ETHOXY-2-BENZOTHIAZOLESULFONAMIDE 452-35-7 C9H10N2O3S2
mersalyl mersalyl 492-18-2 C13H16HgNO6.Na
HYDROFLUMETHIAZIDE HYDROFLUMETHIAZIDE 135-09-1 C8H8F3N3O4S2
mefruside mefruside 7195-27-9 C13H19ClN2O5S2
CYCLOTHIAZIDE CYCLOTHIAZIDE 2259-96-3 C14H16ClN3O4S2
Methazolamide Methazolamide 554-57-4 C5H8N4O3S2
Methyclothiazide Methyclothiazide 135-07-9 C9H11Cl2N3O4S2
3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE 94-78-0 C11H11N5
5-(N,N-HEXAMETHYLENE)-AMILORIDE 5-(N,N-HEXAMETHYLENE)-AMILORIDE 1428-95-1 C12H18ClN7O
PIPERACILLIN PIPERACILLIN 66258-76-2 C23H27N5O7S
BENZTHIAZIDE BENZTHIAZIDE 91-33-8 C15H14ClN3O4S3
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