ChemicalBook CAS DataBase List 2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine synthesis

13synthesis methods

Product Name:2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine
CAS Number:864377-31-1
Molecular formula:C21H14BrN3
Molecular Weight:388.26

2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine is an intermediate in organic synthesis and pharmaceutical intermediate, which is mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis. Its synthesis method is：2-chloro-4,6-diphenyl-1,3,5-triazine in THF was added (3-bromophenyl) borate, and tetrakis (triphenylphosphine) palladium, and the mixture was stirred. Subsequently, thereto added potassium carbonate saturated aqueous solution, and the resulting mixture was heated at reflux at 80℃ for 12 hours. When the reaction is complete and purified to give 2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine.

3132-99-8 Synthesis

3132-99-8
502 suppliers
$5.00/10g

1670-14-0 Synthesis

1670-14-0
435 suppliers
$6.00/10g

2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

864377-31-1
236 suppliers
$9.00/250mg

Yield:864377-31-1 83%

Reaction Conditions:

with nickel diacetate;sodium carbonate in toluene at 110; for 30 h;Reagent/catalyst;

Steps:

2 The compound 2-(3-bromophenyl)-4,6-diphenyl-1,3,5-triazine (Compound 11) provided by the present invention can be synthesized by the following synthesis method.
100mlThree mouthfulsIn the bottleM-bromobenzaldehyde(10.8mmol, 2g),Benzoquinone hydrochloride(21.6mmol, 3.8g), Na2CO3 (21.6 mmol, 2.2 g), Ni(OAc) 2 (1.08 mmol, 0.27 g),The molar ratio is charged at 1:2:2:0.1.The solvent was chosen to be 50 g of toluene.The reaction was controlled to stir at 110 ° C for 30 h.filter,Washed,Recrystallization from absolute ethanol,The obtained cake was vacuum dried to obtain a product of 3.6 g.The yield was 83%.

References:

Hubei Shang Sai Optoelectric Materials Co., Ltd.;Mu Guangyuan;Zhuang Shaoqing;Wang Qi CN108264490, 2018, A Location in patent:Paragraph 0068; 0069; 0070; 0071

FullText

3842-55-5 Synthesis