ChemicalBook CAS DataBase List Triethyl citrate

Triethyl citrate synthesis

10synthesis methods

Product Name:Triethyl citrate
CAS Number:77-93-0
Molecular formula:C12H20O7
Molecular Weight:276.28

By esterification of ethyl alcohol with citric acid.

64-17-5 Synthesis

64-17-5
693 suppliers
$10.00/50g

77-92-9 Synthesis

77-92-9
1591 suppliers
$5.00/10g

77-93-0
518 suppliers
$6.00/25g

Yield:77-93-0 96%

Reaction Conditions:

Stage #1: ethanolwith dicyclohexyl-carbodiimide at 20; for 36 h;Large scale;
Stage #2: citric acid at 35; for 6 h;Autoclave;Large scale;Temperature;

Steps:

3 Example 3

2 kg of N, N-dicyclohexylcarbodiimide was dissolved in 20 ml of absolute ethanol,Then join6.7 kg of mesoporous silica, and the mixture was stirred at room temperature for 36 hours.Dried, and dried at 100 ° C for 8 hours to prepare mesoporous silica-supported N, N-dicyclohexylcarbodiimide condensing agent; 8.7 kg of mesoporous silica Silica-supported N, N-dicyclohexylcarbodiimide condensing agent, 8700 kg of citric acid, 8700 kg of anhydrous ethanol in a reaction kettle at a temperature of 35 ° C and a reaction time of 6 hours. After completion of the reaction, Pore silica loading N, N-dicyclohexyl urea by-product, the filtrate by vacuum distillation to remove the excess ethanol, washing, drying, roasting, that was lemonTriethyl citrateThe yield was 96%.

References:

CN105418416,2016,A Location in patent:Paragraph 0022

64-17-5 Synthesis

64-17-5
693 suppliers
$10.00/50g

77-92-9 Synthesis

77-92-9
1591 suppliers
$5.00/10g