| Identification | More | [Name]
5'-Guanylic acid | [CAS]
85-32-5 | [Synonyms]
5'-GUANOSINE MONOPHOSPHATE
GMP
GMP FREE
GUANOSINE-5'-MONOPHOSPHATE
GUANOSINE 5'-MONOPHOSPHATE FREE ACID N-HYDRATE
GUANOSINE 5'-MONOPHOSPHORIC ACID
GUANYLIC ACID
5’-gmp
5’-guanylicacid
guanidinemonophosphate
guanosine5’-phosphate
guanosinemonophosphate
guanosine 5-(dihydrogen phosphate)
guanosine 5-monophosphate free acid*sigma grade
Guanosine 3ˊ(2ˊ)-monophosphate
GUANOSINE-5'-MONOPHOSPHATE (GMP) FREE ACID 98-100%
GUANOSINE-5'-MONOPHOSPHORIC ACID, 97.0%
[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
GUALOSINE 5'-PHOSPHATE (FEED ACID)
GUANILICACID | [EINECS(EC#)]
201-598-8 | [Molecular Formula]
C10H14N5O8P | [MDL Number]
MFCD00057066 | [Molecular Weight]
363.22 | [MOL File]
85-32-5.mol |
| Chemical Properties | Back Directory | [Definition]
The monophosphoric ester of guanine, i.e., the nucleotide containing guanine, d-ribose, and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding guanosine-2′-phosphate, guanosine-3′-phosphate, and guanosine- | [Melting point ]
220 - 223°C | [storage temp. ]
Store at 0-5°C | [solubility ]
DMSO (Very Slightly, Heated, Sonicated), Water (Slightly, Sonicated) | [Boiling point ]
64 °C(Press: 0.05 Torr) | [density ]
2.47±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
1.86±0.10(Predicted) | [color ]
White to Off-White | [Odor]
at 100.00?%. odorless | [Cosmetics Ingredients Functions]
HUMECTANT
SKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT | [InChI]
1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18) | [InChIKey]
RQFCJASXJCIDSX-UHFFFAOYSA-N | [SMILES]
O=C(NC(N)=N1)C2=C1N(C=N2)C3C(O)C(C(COP(O)(O)=O)O3)O | [LogP]
-2.000 | [Uses]
Biochemical research, flavor potentiator (disodium
salt). | [CAS DataBase Reference]
85-32-5(CAS DataBase Reference) | [EPA Substance Registry System]
85-32-5(EPA Substance) |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [TSCA ]
TSCA listed | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral | [Toxicity]
LDLo intraperitoneal in mouse: 1500mg/kg |
| Hazard Information | Back Directory | [Synthesis]
Under low-temperature conditions, guanosine reacts with a phosphorylating agent (e.g., phosphorus oxychloride POCl3) in an organic solvent (e.g., trimethyl phosphate) to generate the intermediate dichlorophosphate. Subsequently, this intermediate is hydrolyzed in the presence of water or ice to convert into a monophosphate, thereby yielding the target product, 5'-Guanylic acid. | [Purification Methods]
Crystallise it from water and dry it at 110o. [Beilstein 26 III/IV 3910.] |
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