ChemicalBook--->CAS DataBase List--->85-32-5

85-32-5

85-32-5 Structure

85-32-5 Structure
IdentificationMore
[Name]

5'-Guanylic acid
[CAS]

85-32-5
[Synonyms]

5'-GUANOSINE MONOPHOSPHATE
GMP
GMP FREE
GUANOSINE-5'-MONOPHOSPHATE
GUANOSINE 5'-MONOPHOSPHATE FREE ACID N-HYDRATE
GUANOSINE 5'-MONOPHOSPHORIC ACID
GUANYLIC ACID
5’-gmp
5’-guanylicacid
guanidinemonophosphate
guanosine5’-phosphate
guanosinemonophosphate
guanosine 5-(dihydrogen phosphate)
guanosine 5-monophosphate free acid*sigma grade
Guanosine 3ˊ(2ˊ)-monophosphate
GUANOSINE-5'-MONOPHOSPHATE (GMP) FREE ACID 98-100%
GUANOSINE-5'-MONOPHOSPHORIC ACID, 97.0%
[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
GUALOSINE 5'-PHOSPHATE (FEED ACID)
GUANILICACID
[EINECS(EC#)]

201-598-8
[Molecular Formula]

C10H14N5O8P
[MDL Number]

MFCD00057066
[Molecular Weight]

363.22
[MOL File]

85-32-5.mol
Chemical PropertiesBack Directory
[Definition]

The monophosphoric ester of guanine, i.e., the nucleotide containing guanine, d-ribose, and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding guanosine-2′-phosphate, guanosine-3′-phosphate, and guanosine-
[Melting point ]

220 - 223°C
[storage temp. ]

Store at 0-5°C
[solubility ]

DMSO (Very Slightly, Heated, Sonicated), Water (Slightly, Sonicated)
[Boiling point ]

64 °C(Press: 0.05 Torr)
[density ]

2.47±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

1.86±0.10(Predicted)
[color ]

White to Off-White
[Odor]

at 100.00?%. odorless
[Cosmetics Ingredients Functions]

HUMECTANT
SKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT
[InChI]

1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)
[InChIKey]

RQFCJASXJCIDSX-UHFFFAOYSA-N
[SMILES]

O=C(NC(N)=N1)C2=C1N(C=N2)C3C(O)C(C(COP(O)(O)=O)O3)O
[LogP]

-2.000
[Uses]

Biochemical research, flavor potentiator (disodium salt).
[CAS DataBase Reference]

85-32-5(CAS DataBase Reference)
[EPA Substance Registry System]

85-32-5(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
[WGK Germany ]

WGK 3
[TSCA ]

TSCA listed
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
[Toxicity]

LDLo intraperitoneal in mouse: 1500mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

D(+)-Glucose-->Ribonucleic acid-->Guanosine-->guanosine 3'-(dihydrogen phosphate)-->2'-guanylic acid-->D-Ribose-->Guanine
[Preparation Products]

Disodium 5'-Inosinate-->Acyclovir-->Ribavirin-->Guanosine 5'-monophosphate disodium salt-->CALCIUM5'-GUANYLATE-->5'-Guanylic acid, dipotassium salt-->[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate-->GDP-->guanosine 5'-phosphoimidazolide
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate(85-32-5).msds
Spectrum DetailBack Directory
[Spectrum Detail]

5'-Guanylic acid(85-32-5)1HNMR
5'-Guanylic acid(85-32-5)13CNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

85-32-5(sigmaaldrich)
Hazard InformationBack Directory
[Synthesis]

Under low-temperature conditions, guanosine reacts with a phosphorylating agent (e.g., phosphorus oxychloride POCl3) in an organic solvent (e.g., trimethyl phosphate) to generate the intermediate dichlorophosphate. Subsequently, this intermediate is hydrolyzed in the presence of water or ice to convert into a monophosphate, thereby yielding the target product, 5'-Guanylic acid.
[Purification Methods]

Crystallise it from water and dry it at 110o. [Beilstein 26 III/IV 3910.]
85-32-5 suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Hongene Biotech Corporation  
Telephone: 021-64757213
Website: http://www.hongene.com/
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Telephone: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Telephone: 021-50135380
Website: www.shchemsky.com
Company Name: Dalian Meilun Biotech Co., Ltd.  
Telephone: 0411-62910999 13889544652
Website: http://www.meilunbio.com/
Company Name: ShangHai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: Hangzhou Sage Chemical Co., Ltd.  
Telephone: +86057186818502 13588463833
Website: www.sagechem.com
Company Name: Beijing HuaMeiHuLiBiological Chemical   
Telephone: 010-56205725
Website: www.huabeibiochem.com
Company Name: Shanghai Tauto Biotech Co., Ltd.  
Telephone: 021-51320588
Website: http://www.tautobiotech.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 021-021-33632979 15002134094
Website: https://www.targetmol.cn/
Company Name: Shanghai TaoSu Biochemical Technology Co., Ltd.  
Telephone: 021-33632979
Website: www.tsbiochem.com
Company Name: Shanghai BeiZhuo Biotech Co., Ltd.  
Telephone: 021-61119791,13386096464
Website: www.chemicalbook.com/ShowSupplierProductsList16081/0_EN.htm
Company Name: Quality Control Solutions Ltd.  
Telephone: 0755-66853366 13670046396
Website: www.qcsrm.com
Company Name: Wuxi Zhongkun Biochemical Technology Co., Ltd.  
Telephone: 0510-85629785 18013409632;
Website: www.reading-chemicals.com
Company Name: Finetech Industry Limited  
Telephone: 027-87465837 19945049750
Website: https://www.finetechchem.com/
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
Telephone: 15221275939 15221275939
Website: www.macklin.cn
Company Name: Hubei Jusheng Technology Co.,Ltd  
Telephone: 027-59599241 18871490274
Website: http://www.jushengtech.com
Company Name: Sigma-Aldrich  
Telephone: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Tags:85-32-5 Related Product Information
7758-87-4 134-58-7 7601-54-9 31096-47-6 7779-90-0 5550-12-9 73-40-5 55896-93-0 118-00-3 67-07-2 154-42-7 59277-89-3 2004-07-1 56-40-6 5988-19-2 7722-76-1 59-30-3 2004-06-0