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1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose Produkt Beschreibung

Sucralose Struktur
56038-13-2
CAS-Nr.
56038-13-2
Bezeichnung:
1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose
Englisch Name:
Sucralose
Synonyma:
TGS;E955;SUCRALOSE;SPLENDA [R];Sucralose99%;SUCRALOSE(P);ctopyranoside;loro-4-deoxy-;Sucralose 0.1;Sucralose, NF
CBNumber:
CB9363034
Summenformel:
C12H19Cl3O8
Molgewicht:
397.63
MOL-Datei:
56038-13-2.mol

1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose Eigenschaften

Schmelzpunkt:
115-1018°C
Siedepunkt:
104-107 C
alpha 
D +68.2° (c = 1.1 in ethanol)
Dichte
1.375 g/cm
storage temp. 
2-8°C
Löslichkeit
Do you have solubility information on this product that you would like to share
Aggregatzustand
Powder
pka
12.52±0.70(Predicted)
Farbe
White
PH
6-8 (100g/l, H2O, 20°C)
Optische Aktivität
[α]/D 86.0±2.0°, c = 1 in H2O
Wasserlöslichkeit
Soluble in Water.
Merck 
14,8880
BRN 
3654410
CAS Datenbank
56038-13-2(CAS DataBase Reference)
EPA chemische Informationen
.alpha.-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranosyl 4-chloro-4-deoxy- (56038-13-2)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-37/39-24/25
WGK Germany  3
RTECS-Nr. LW5440140
HS Code  2932 14 00
Giftige Stoffe Daten 56038-13-2(Hazardous Substances Data)
Toxizität LD50 orally in Rabbit: > 10000 mg/kg

1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

Off-White Amorphous Solid

Chemische Eigenschaften

Sucralose is a white to off-white colored, free-flowing, crystalline powder.

History

Sucralose, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl- 4-chloro-4-deoxy-α-D-galactopyranoside, is a trichloro-galactosucrose sweetener developed by the British sugar company Tate & Lyle during the 1970s (U.S. Pat. 4,343,934 (Aug. 10, 1982), M. R. Jenner and D. Waite (to Talres Development), (U.S. Pat. 4,362,869 (Dec. 7, 1982), M. R. Jenner and co-workers (to Talres Development), and (U.S. Pat. 4,435,440 (Mar. 6, 1984), L. Hough, S. P. Phadnis, and R. A. Khan (to Tate & Lyle). It was licensed to McNeil-PPC, Inc., a Johnson & Johnson subsidiary, in the United States until a new agreement took place in February, 2004. McNeil Nutritionals retained ownership of SPLENDA Brand and the right for its worldwide retail and food service business. Tate & Lyle became the sole manufacturer of SPLENDA Brand sucralose and owned the right for its worldwide ingredient sales.

Verwenden

High intensity sweetener manufactured by replacing three hydroxyl groups on the sucrose molecule with three chlorine atoms. The results are a sweetener of 0 cal that is not digested. It is 600 times as sweet as sugar with a similar flavor profile. It is heat stable, readily soluble, and maintains its stability at elevated temperatures. It has been approved for use in specific categories that include baked products, beverages, confectioneries, and certain desserts and toppings.

Verwenden

Sucralose (1,6-dichloro-1,6-dideoxy-p-fructofuranosyl-4-chloro-oc- D-galactopyra- noside) is a nonnutritive sweetener based on sucrose. It is selectively chlorinated and the glycoside link between the two rings is resistant to hydrolysis by acid or enzymes, so it is not metabolized. It has 400 to 800 times the sweetness of sucrose, is very soluble in water, and is stable in heat. It can be used in food products that are baked or fried.
Sucralose is produced by the selective chlorination of the sucrose molecule using a patented process by Tate and LyIe that replaces the three hydroxyl groups (OH) with three chlorine (Cl) atoms.
This modified sugar is minimally absorbed by the body and passes out unchanged. It was approved for use in foods and beverages in 1999 in the United States.

Verwenden

A low-calorie artificial sweetener

Verwenden

antiprotozoal

Definition

ChEBI: A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.

Vorbereitung Methode

Sucralose may be prepared by a variety of methods that involve the selective substitution of three sucrose hydroxyl groups by chlorine. Sucralose can also be synthesized by the reaction of sucrose (or an acetate) with thionyl chloride.

Pharmazeutische Anwendungen

Sucralose is used as a sweetening agent in beverages, foods, and pharmaceutical applications. It has a sweetening power approximately 300–1000 times that of sucrose and has no aftertaste. It has no nutritional value, is noncariogenic, does not promote dental caries, and produces no glycemic response.

Sicherheit(Safety)

Sucralose is generally regarded as a nontoxic and nonirritant material and is approved, in a number of countries, for use in food products. Following oral consumption, sucralose is mainly unabsorbed and is excreted in the feces.
The WHO has set an acceptable daily intake for sucralose of up to 15 mg/kg body-weight.
LD50 (mouse, oral): > 16 g/kg
LD50 (rat, oral): > 10 g/kg

Lager

Sucralose is a relatively stable material. In aqueous solution, at highly acidic conditions (pH < 3), and at high temperatures (≤35℃), it is hydrolyzed to a limited extent, producing 4-chloro-4- deoxygalactose and 1,6-dichloro-1,6-dideoxyfructose. In food products, sucralose remains stable throughout extended storage periods, even at low pH. However, it is most stable at pH 5–6.
Sucralose should be stored in a well-closed container in a cool, dry place, at a temperature not exceeding 21℃. Sucralose, when heated at elevated temperatures, may break down with the release of carbon dioxide, carbon monoxide, and minor amounts of hydrogen chloride.

Regulatory Status

The FDA, in April 1998, approved sucralose for use as a tabletop sweetener and as an additive in a variety of food products. In the UK, sucralose was fully authorized for use in food products in 2005. It is also accepted for use in many other countries worldwide. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.

1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 501)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
JIANGXI ALPHA HI-TECH PHARMACEUTICAL CO., LTD
86-51085010237
overseamarketing@alphahi-tech.com CHINA 42 58
NANJING SUNSHINE BIOTECH CO.,LTD
+86-25-86189929
+86-25-86189616 brian@sunshine-bio.com CHINA 128 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 3001 55
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1010 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29959 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58

56038-13-2(1,6-Dichlor-1,6-didesoxy-β-D-fructofuranosyl-4-chlor-4-desoxy-α-D-galaktose)Verwandte Suche:


  • 1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl4-chloro-4-deoxy-alpha-d-gala
  • 4,1’,6’-trichloro-4,1’,6’-trideoxy-galacto-sucrose
  • alpha-d-galactopyranoside,1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl4-ch
  • ctopyranoside
  • Sucralose in stock GMP Factory
  • 1,6-dichloro-1
  • 4,1',6'-trichlorogalactosucrose
  • loro-4-deoxy-
  • 1,6-DICHLORO-1,6-DIDEOXY-BETA-D-FRUCTOFURANOSYL-4-CHLORO-4-DEOXY-ALPHA-D-GALACOTOPYRANOSIDE
  • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactose
  • SUCRALOSE
  • TRICHLOROSUCROSE
  • 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside
  • SUCRALOSE FCC (TRICHLOROGALACTOSUCROSE)
  • SucraloseC12H19Cl3O8
  • Sucralose98%Min.
  • Sucralose99%
  • Steviosides90%
  • Sucralose&Int.
  • SPLENDA [R]
  • .alpha.-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranosyl 4-chloro-4-deoxy-
  • trichlorogalactosucrose
  • 4,16trichloro-4,16trideoxy pentagalactosucrose
  • SUCRALOSE /4,1'',6'',-TRICHLORO-4,1'',6''TRIDEOXY-PENTAGALACTOSUCROSE
  • SUCRALOSE(TRICHLOROSUCROSE)
  • Sucralose 98.0-102.0%
  • 4,1,6-TRICHLOROGALACTOSUCROSE (SUCRALOSE)
  • 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galacotopyranoside
  • 1,6-Dichloro-1,6-Dideoxy-B-D-Fructofuranosyl-4-Chloro-4-Deoxy-A-D-Galacotopyranoside
  • (2R,3R,4R,5R,6R)-2-{[(2S,3R,4R,5R)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydro furan-2-yl]oxy}-
  • Sucralose 0.1
  • α-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-
  • E955,Trichlorosucrose
  • (2R,3R,4R,5R,6R)-2-{[(2S,3R,4R,5R)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yl]oxy}-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol (Sucralose)
  • TGS
  • E955, Trichlorosucrose, 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
  • 4,1’,6’-trichloro-galactosucorose
  • trichlorosucorose
  • 1',4,6'-Trichloro-galacto-sucrose
  • 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside
  • (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxy-oxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
  • (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
  • (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]oxy-5-chloro-6-methylol-tetrahydropyran-3,4-diol
  • (2R,3R,4R,5R,6R)-2-((2R,3S,4S,5S)-2,5-Bis(Chloromethyl)-3,4-Dihydroxytetrahydrofuran-2-Yloxy)-5-Chloro-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4-Diol
  • SUBERIC ACID(RG)
  • E955
  • Sucralose,1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose
  • Sucralose (400 mg)
  • Sucralose (400 mg)G1E3170.998mg/mg(ai)
  • Sucralose, FCC
  • Sucralose, NF
  • 2-{[2,5-bis(chloroMethyl)-3,4-dihydroxyoxolan-2-yl]oxy}-5-chloro-6-(hydroxyMethyl)oxane-3,4-diol
  • 1-(1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl)-4-chloro-4-deoxy-alpha-D-galactopyranoside
  • SUCRALOSE(P)
  • Sucralose ,98%
  • Sucralose (E955
  • Sucralose >
  • Sucralose Standard
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