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Sucralose

Sucralose
Sucralose structure
CAS No.
56038-13-2
Chemical Name:
Sucralose
Synonyms
TGS;E955;SUCRALOSE;SPLENDA [R];SUCRALOSE(P);Sucralose99%;ctopyranoside;loro-4-deoxy-;Sucralose, NF;Sucralose 0.1
CBNumber:
CB9363034
Molecular Formula:
C12H19Cl3O8
Formula Weight:
397.63
MOL File:
56038-13-2.mol

Sucralose Properties

Melting point:
115-1018°C
Boiling point:
104-107 C
alpha 
D +68.2° (c = 1.1 in ethanol)
Density 
1.375 g/cm
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Do you have solubility information on this product that you would like to share
form 
Powder
color 
White
PH
6-8 (100g/l, H2O, 20°C)
optical activity
[α]/D 86.0±2.0°, c = 1 in H2O
Water Solubility 
Soluble in Water.
Merck 
14,8880
BRN 
3654410
CAS DataBase Reference
56038-13-2(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  3
RTECS  LW5440140
HS Code  2932 14 00
Toxicity LD50 orally in Rabbit: > 10000 mg/kg

Sucralose price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 69293 Sucralose ≥98.0% (HPLC) 56038-13-2 100g $122 2018-11-13 Buy
Sigma-Aldrich 1623626 Sucralose United States Pharmacopeia (USP) Reference Standard 56038-13-2 400mg $399.35 2018-11-13 Buy
TCI Chemical S0839 Sucralose >98.0%(HPLC) 56038-13-2 5g $35 2018-11-22 Buy
TCI Chemical S0839 Sucralose >98.0%(HPLC) 56038-13-2 25g $99 2018-11-22 Buy
Alfa Aesar J66736 Sucralose 98% 56038-13-2 100g $88.2 2018-11-20 Buy

Sucralose Chemical Properties,Uses,Production

Chemical Properties

Off-White Amorphous Solid

Chemical Properties

Sucralose is a white to off-white colored, free-flowing, crystalline powder.

Uses

A low-calorie artificial sweetener

Uses

antiprotozoal

Uses

High intensity sweetener manufactured by replacing three hydroxyl groups on the sucrose molecule with three chlorine atoms. The results are a sweetener of 0 cal that is not digested. It is 600 times as sweet as sugar with a similar flavor profile. It is heat stable, readily soluble, and maintains its stability at elevated temperatures. It has been approved for use in specific categories that include baked products, beverages, confectioneries, and certain desserts and toppings.

Uses

Sucralose (1,6-dichloro-1,6-dideoxy-p-fructofuranosyl-4-chloro-oc- D-galactopyra- noside) is a nonnutritive sweetener based on sucrose. It is selectively chlorinated and the glycoside link between the two rings is resistant to hydrolysis by acid or enzymes, so it is not metabolized. It has 400 to 800 times the sweetness of sucrose, is very soluble in water, and is stable in heat. It can be used in food products that are baked or fried.
Sucralose is produced by the selective chlorination of the sucrose molecule using a patented process by Tate and LyIe that replaces the three hydroxyl groups (OH) with three chlorine (Cl) atoms.
This modified sugar is minimally absorbed by the body and passes out unchanged. It was approved for use in foods and beverages in 1999 in the United States.

Definition

ChEBI: A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.

Production Methods

Sucralose may be prepared by a variety of methods that involve the selective substitution of three sucrose hydroxyl groups by chlorine. Sucralose can also be synthesized by the reaction of sucrose (or an acetate) with thionyl chloride.

Pharmaceutical Applications

Sucralose is used as a sweetening agent in beverages, foods, and pharmaceutical applications. It has a sweetening power approximately 300–1000 times that of sucrose and has no aftertaste. It has no nutritional value, is noncariogenic, does not promote dental caries, and produces no glycemic response.

Safety

Sucralose is generally regarded as a nontoxic and nonirritant material and is approved, in a number of countries, for use in food products. Following oral consumption, sucralose is mainly unabsorbed and is excreted in the feces.
The WHO has set an acceptable daily intake for sucralose of up to 15 mg/kg body-weight.
LD50 (mouse, oral): > 16 g/kg
LD50 (rat, oral): > 10 g/kg

storage

Sucralose is a relatively stable material. In aqueous solution, at highly acidic conditions (pH < 3), and at high temperatures (≤35℃), it is hydrolyzed to a limited extent, producing 4-chloro-4- deoxygalactose and 1,6-dichloro-1,6-dideoxyfructose. In food products, sucralose remains stable throughout extended storage periods, even at low pH. However, it is most stable at pH 5–6.
Sucralose should be stored in a well-closed container in a cool, dry place, at a temperature not exceeding 21℃. Sucralose, when heated at elevated temperatures, may break down with the release of carbon dioxide, carbon monoxide, and minor amounts of hydrogen chloride.

Regulatory Status

The FDA, in April 1998, approved sucralose for use as a tabletop sweetener and as an additive in a variety of food products. In the UK, sucralose was fully authorized for use in food products in 2005. It is also accepted for use in many other countries worldwide. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.

Sucralose Preparation Products And Raw materials

Raw materials

Preparation Products


Sucralose Suppliers

Global( 379)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21714 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 892 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1017 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 699 58

View Lastest Price from Sucralose manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-03 Sucralose in stock GMP Factory
56038-13-2
US $1.00 / KG 1KG GMP Factory in China Top 3 largest production capacity Factory Chemwill Asia Co.,Ltd.
2019-04-19 Sucralose
56038-13-2
US $1.00 / kg 1kg 99% 10 tons hdzhl biotechnology co., ltd
2018-12-16 Sucralose
56038-13-2
US $8.00 / kg 1kg 98% 10MT career henan chemical co

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