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Vatalanib base

Vatalanib base Structure
Vatalanib base structure
CAS No.
212141-54-3
Chemical Name:
Vatalanib base
Synonyms
VataL;VATALANIB;PTK787 2HCl;VATALANIB BASE;Vatalanib 2HCL;PTK787 free base;PTK/ZK free base;Vatalanib (PTK787);anib (PTK787) 2HCL;CGP-79787 free base
CBNumber:
CB2173616
Molecular Formula:
C20H15ClN4
Molecular Weight:
346.81
MDL Number:
MFCD08458963
MOL File:
212141-54-3.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19
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Vatalanib base Properties

Melting point 209-212°
Boiling point 587.8±50.0 °C(Predicted)
Density 1.330±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic
form solid
pka 5.46±0.10(Predicted)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms vatalanib
FDA UNII 5DX9U76296
NCI Drug Dictionary vatalanib

SAFETY

Risk and Safety Statements

HS Code  2933399990

Vatalanib base price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology A3969 Vatalanib 212141-54-3 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Apolloscientific BIFK0006 Vatalanib 212141-54-3 5mg $73 2021-12-16 Buy
Apolloscientific BIFK0006 Vatalanib 212141-54-3 10mg $116 2021-12-16 Buy
American Custom Chemicals Corporation API0004576 VATALANIB 95.00% 212141-54-3 10MG $154.35 2021-12-16 Buy
Apolloscientific BIFK0006 Vatalanib 212141-54-3 25mg $218 2021-12-16 Buy
Product number Packaging Price Buy
A3969 10mM(in 1mL DMSO) $50 Buy
BIFK0006 5mg $73 Buy
BIFK0006 10mg $116 Buy
API0004576 10MG $154.35 Buy
BIFK0006 25mg $218 Buy

Vatalanib base Chemical Properties,Uses,Production

Uses

anti-viral

Uses

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.

Definition

ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.

Vatalanib base synthesis

87-41-2
212141-54-3
Synthesis of Vatalanib base from Phthalide

Vatalanib base Preparation Products And Raw materials

Raw materials

Pyridine, 4-(bromomethyl)- (9CI) 4-(Chloromethyl)pyridine 1-CHLORO-4-(4-PYRIDINYLMETHYL)PHTHALAZINE 4-(4-PYRIDYLMETHYL)-1(2H)-PHTALAZINONE 3-HYDROXY-2-PYRIDIN-4-YL-INDEN-1-ONE
Phthalide 1-Chloro-4-iodobenzene 4-Chlorobenzenamine hydrochloride Phthalonitrile 4-Chloroaniline
4-Bromochlorobenzene

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Preparation Products

Vatalanib base Suppliers

Global( 114)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
Hebei Yanxi Chemical Co., Ltd. 		58
SIMAGCHEM CORP 		58
TargetMol Chemicals Inc. 		58
Finetech Industry Limited 		58

View Lastest Price from Vatalanib base manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vatalanib base pictures 2019-12-24 Vatalanib base
212141-54-3
 US $1.00 / g 100g 98%min G/KG/T Career Henan Chemical Co
Vatalanib base pictures 2019-12-24 Vatalanib base
212141-54-3
 US $1.00 / g 100g 98%min G/KG/T Career Henan Chemical Co

Vatalanib base Spectrum

Vatalanib base(212141-54-3)1HNMR

212141-54-3(Vatalanib base)Related Search:

Chlorodimethylphenylsilane Trimethylphenylammonium chloride 4-Methylpyridine 2,6-Lutidine 2-Chloro-5-chloromethylpyridine
Triethanolamine Dibenzylamine Bis(2-ethylhexyl)amine 2,4,6-Collidine Triallylamine
Azamethiphos Vatalanib Dihydrochloride 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE 4-(4-AMINOPHENOXY)PYRIDINE Sorafenib
4-(4-Aminophenoxy)-N-methylpicolinamide Vatalanib base

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N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)- 1-Phthalazinamine 1-PhthalazinaMine, N-(4-chlorophenyl)-4-(4-pyridinylMethyl)- Vatalanib (PTK787) Dihydrochloride Base Pynasunate, ZK222584, CGP-79787, PTK 787 (4-Chloro-phenyl)-(4-pyridin-4-ylmethyl-phthalazin-1-yl)-amine Vatalanib (free base) VATALANIB SORAFENIB BASE VATALANIB Vatalanib 2HCL VATALANIB BASE Vatalanib free base (PTK787 free base PTK787 free base PTK787 FREE BASE; PTK/ZK FREE BASE; CGP-79787 FREE BASE; ZK-222584 FREE BASE CGP-79787 free base PTK/ZK free base ZK-222584 free base) PTK787 2HCl ZK 222584 (CPG-79787) 2HCL;PTK787 2HCL Vatalanib (PTK787) anib (PTK787) 2HCL VataL 212141-54-3 Antineoplastic