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3-(Aminomethyl)pyridine

3-(Aminomethyl)pyridine Structure
3-(Aminomethyl)pyridine structure
CAS No.
3731-52-0
Chemical Name:
3-(Aminomethyl)pyridine
Synonyms
pyridin-3-ylmethanamine;Picolamine;3-PICOLYLAMINE;3AMPY;NSC 59706;Picolamin;-Aminomethyl;m-Picolylamine;AKOS BBS-00003679;3-Picolylamine>
CBNumber:
CB2284635
Molecular Formula:
C6H8N2
Molecular Weight:
108.14
MDL Number:
MFCD00006412
MOL File:
3731-52-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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3-(Aminomethyl)pyridine Properties

Melting point −21 °C(lit.)
Boiling point 73-74 °C1 mm Hg(lit.)
Density 1.062 g/mL at 25 °C(lit.)
refractive index n20/D 1.551(lit.)
Flash point 213 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Chloroform, Ethyl Acetate, Methanol
form clear liquid
pka 8.34±0.29(Predicted)
color Colorless to Light yellow
PH 11-12 (100g/l, H2O, 20℃)
Water Solubility FREELY SOLUBLE
Sensitive Air Sensitive
BRN 108056
Henry's Law Constant 4.3×102 mol/(m3Pa) at 25℃, Du et al. (2017)
InChI 1S/C6H8N2/c7-4-6-2-1-3-8-5-6/h1-3,5H,4,7H2
InChIKey HDOUGSFASVGDCS-UHFFFAOYSA-N
SMILES NCc1cccnc1
CAS DataBase Reference 3731-52-0(CAS DataBase Reference)
FDA UNII 31LA41942J
NIST Chemistry Reference Picolamine(3731-52-0)
EPA Substance Registry System 3-Pyridinemethanamine (3731-52-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H290-H314
Precautionary statements  P234-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,Xi
Risk Statements  34-37-36/37/38
Safety Statements  26-36/37/39-45-25-36
RIDADR  UN 2735 8/PG 2
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29333999
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Met. Corr. 1
Skin Corr. 1B
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
0
3 0

3-(Aminomethyl)pyridine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A65409 3-Picolylamine ≥99% 3731-52-0 5g $34.2 2026-04-30 Buy
Sigma-Aldrich A65409 3-Picolylamine ≥99% 3731-52-0 100g $83.4 2026-04-30 Buy
TCI Chemical P0762 3-Picolylamine >99.0%(GC) 3731-52-0 25mL $19 2026-04-30 Buy
TCI Chemical P0762 3-Picolylamine >99.0%(GC) 3731-52-0 100mL $50 2026-04-30 Buy
Usbiological 231425 3-(Aminomethyl)pyridine 99+% ≥99% 3731-52-0 5ml $156 2026-06-03 Buy
Product number Packaging Price Buy
A65409 5g $34.2 Buy
A65409 100g $83.4 Buy
P0762 25mL $19 Buy
P0762 100mL $50 Buy
231425 5ml $156 Buy

3-(Aminomethyl)pyridine Chemical Properties, Uses, Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHLY YELLOW LIQUID

Uses

It finds its application as a rubefacient.

Application

3-(Aminomethyl)pyridine can be used to prepare metal complexes. A number of complexes of cobalt(II), nickel(II) and copper(II) thiocyanates, chlorides and bromides with 3-pyridine amine were prepared and the stereochemical configurations of these complexes were deduced using spectroscopy and magnetism, and the decomposition of the complexes was studied by thermogravimetry and differential thermal analysis[2].

Synthesis

Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts. A natural product inspired rapid access of 3-(aminomethyl)pyridine by one-pot reaction of 1-amidopyridin-1-ium salt with aminal followed by reductive cleavage of the N–N bond is developed. This C3-selective formal C–H activation of pyridine features a traceless umpolung of the 1-amidopyridin-1-ium salt toward a Mannich type C–C bond formation of the in situ generated 1-amido-2-dialkylamino-1,2-dihydropyridine intermediate[1].

References

[1] TANG P, XIAO D, WANG B. Synthesis of 3-(aminomethyl)pyridine by traceless C3-selective umpolung of 1-amidopyridin-1-ium salts[J]. Chemical Communications, 2017. DOI:10.1039/C6CC09582H.
[2] J. R. ALLAN  M. J P  A D Paton. The preparation, characterisation and thermal analysis studies on complexes of cobalt(II), nickel(II), and copper(II) with 3-picolylamine[J]. Journal of Thermal Analysis and Calorimetry, 1985. DOI:10.1007/BF01913603.

3-(Aminomethyl)pyridine Preparation Products And Raw materials

Raw materials

Lithium Aluminum Hydride 3-Cyanopyridine 3-Pyridinemethanol Carbonylchlorohydrotris(triphenylphosphine)ruthenium Ammonia
4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene 2-Methyl-2-butanol

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Preparation Products

VACOR 3-Pyridinemethanamine 1-oxide 3-(Aminomethyl)-1-methylpiperidine 3-N-Boc-Aminomethylpiperidine 1,3-Dioxo-2-pyridin-3-ylmethyl-2,3-dihydro-1H-isoindole-5-carboxylic acid
2-Cyano-N-(3-pyridinylmethyl)acetamide (4-Bromo-benzyl)-pyridin-3-ylmethyl-amine 4-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamide Methyl 3-[(3-pyridinylmethyl)amino]propanoate 2-Bromo-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide
4-(prop-2-ynylaMino)-N-(pyridin-3-ylMethyl)benzaMide

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3-(Aminomethyl)pyridine Suppliers

Global Suppliers ( 400)
Supplier Tel Email Country ProdList Advantage
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Changzhou Jintan Maosheng Chemical Plant 13382827140 maoshengchem@126.com China 70 58
Hunan Daolin Biotechnology Co. , Ltd. 18974846212 1876969603@qq.com China 57 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Weifang Siyuan Chemical Co., Ltd. 58
Changzhou Jintan Maosheng Chemical Plant 58
Hunan Daolin Biotechnology Co. , Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61

View Latest Price from 3-(Aminomethyl)pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Picolamine pictures 2026-09-02 Picolamine
3731-52-0
 $1.00-122.00 1KG 99% Henan Fengda Chemical Co., Ltd
Picolamine pictures 2026-07-15 Picolamine
3731-52-0
 $29.00 99.64% 10g TargetMol Chemicals Inc.
3-(Aminomethyl)pyridine pictures 2021-07-13 3-(Aminomethyl)pyridine
3731-52-0
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
  • Picolamine pictures
  • Picolamine
    3731-52-0
  • $1.00-122.00
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Picolamine pictures
  • Picolamine
    3731-52-0
  • $29.00
  • 99.64%
  • TargetMol Chemicals Inc.

3-(Aminomethyl)pyridine Spectrum

3-(Aminomethyl)pyridine(3731-52-0)MS3-(Aminomethyl)pyridine(3731-52-0)1HNMR3-(Aminomethyl)pyridine(3731-52-0)13CNMR3-(Aminomethyl)pyridine(3731-52-0)IR13-(Aminomethyl)pyridine(3731-52-0)IR23-(Aminomethyl)pyridine(3731-52-0)Raman

3731-52-0 (3-(Aminomethyl)pyridine) Related Search:

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3-Pyridylmethanamine Pyridine-3-methanamine 3-(Aminomethyl)pyrid 3-(AMinoMethyl)pyridine, 99+% 100ML 1-(Pyridin-3-yl)MethanaMine NSC 59706 3-(AMINOMETHYL)PYRIDINE FOR SYNTHESIS (Pyridin-3-yl)methylamine, Nicotinylamine C-PYRIDIN-3-YL-METHYLAMINE 3-PicolylaMine >=99% 3-pyridinylmethylamine 3-(AMINOMETHYL)PYRIDINE 3AMPY 3-PYRIDINEMETHANAMINE 3-PYRIDYLMETHYLAMINE OMEGA-AMINO-B-PICOLINE TIMTEC-BB SBB004351 RARECHEM AL BW 0100 AKOS BBS-00003679 -(Aminomethyl)pyridine 3-Pyridinemethaneamine 3-Pyridinemethylamine 3-Pyridinylmethanamine -Aminomethyl Pyridine, 3-(aminomethyl)- 3-(AMINOMETHYL)PYRIDINE, 99+% 3-(aminomehtyl)pyridine (Pyridin-3-yl)methylamine 3-(AMINOMETHYL)PYRIDINE:3-PICOLYLAMINE 3-(AMINOMETHYL)PYRIDINE, 97+% 3-AMINOMETHYL PYRIDINE C-PYRIDIN-3-YL-METHYLAMINE 3-pyridinylmethylammonium 3-(Aminomethyl)pyridine, 99%, for synthesis 3-Picolylamine> 3-(Aminomethyl)pyridine 3731-52-0 Picolamine Picolamin Picolamine, 10 mM in DMSO 3-(Aminomethyl)pyridine, 95% 3-PICOLYLAMINE pyridin-3-ylmethanamine m-Picolylamine 3731-52-0 Building Blocks Heterocyclic Building Blocks Pyridines AMINE C6 Building Blocks Chemical Synthesis Heterocyclic Building Blocks Pyridines Aromatics Heterocycles Miscellaneous Reagents Nitrogen cyclic compounds Pyridines derivates Amines