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Diphenoxylate

Diphenoxylate
Diphenoxylate structure
CAS No.
915-30-0
Chemical Name:
Diphenoxylate
Synonyms
DIPHENOXYLATE;DiphenoxyleteHCl;Diphenoxyletehydrochloride;HYPPXZBJBPSRLK-UHFFFAOYSA-N;Diphenoxylate hydrochloride CP2000,BP98;ethyl1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate;2,2-diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile;1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-isonipecoticaciethylester;1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecoticacidethylester;1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-isonipecoticacidethylester
CBNumber:
CB3301641
Molecular Formula:
C30H32N2O2
Formula Weight:
452.59
MOL File:
915-30-0.mol

Diphenoxylate Properties

pka
pKa 7.1 (Uncertain)
CAS DataBase Reference
915-30-0(CAS DataBase Reference)
NIST Chemistry Reference
Diphenoxylate(915-30-0)

SAFETY

Hazard Codes  T+
Risk Statements  26/27/28-42/43
Safety Statements  22-26-45
Hazardous Substances Data 915-30-0(Hazardous Substances Data)

Diphenoxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

Diphenoxylate Chemical Properties,Uses,Production

Uses

Antiperistaltic.

Definition

ChEBI: A piperidinecarboxylate ester that is the ethyl ester of difenoxin.

brand name

Diarphem;Diarsed-neomycin;Diatro;Eldox;Logen;Lomanate;Lomax;Lomotil liquid;Lonox;Protector;Reasec;Saleton;Sedistal.

World Health Organization (WHO)

Diphenoxylate, a derivative of pethidine without analgesic activity, is used in the symptomatic treatment of acute and chronic diarrhoea to reduce intestinal motility. There is no clear evidence that it has any beneficial effect in diminishing fluid losses and it has been associated with central nervous system toxicity, particularly in children, which results in anorexia, nausea and vomiting, headache, drowsiness, confusion, insomnia, dizziness, restlessness, euphoria and depression. The World Health Organization recommends that diphenoxylate should not be used for the management of diarrhoea in children and many countries have since withdrawn products containing this compound indicated for paediatric use. (Reference: (WHORUD) The Rational Use of Drugs, , , 1990)

General Description

Diphenoxylate is a weak opioid agonist and isavailable combined with atropine (Lomotil) for use as an antidiarrhealagent. At low doses, the opioid effect is minimal,and the atropine is added to dissuade abuse. One studyfound both codeine and loperamide to be superior to diphenoxylatefor treating chronic diarrhea.83 The manufacturerhas strict dosing guidelines for pediatric use because opioidintoxication and deaths from diphenoxylate have beenreported.

Diphenoxylate Preparation Products And Raw materials

Raw materials

Preparation Products


Diphenoxylate Suppliers

Global( 43)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 541 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20331 58
Henan Hekang Biological Co., Ltd. 13849026065
0371-55886196 2022168780qq@com China 60 58
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216
+86-571-82880190 info@yuhaochemical.com China 9409 52
(CSR Factory)China Skyrun Industrial CO.,ltd Please Email
manager@chinaskyrun.com sales@chinaskyrun.com China 12128 58
Nanjing Sunlida Biological Technology Co., Ltd. 025-58378339;025-57798810
025-57019371 sales@sunlidabio.com China 3823 55
HBCChem, Inc. +1-510-219-6317
+1-650-486-1361 sales@hbcchem.com United States 10667 60
Wuhan Dahua Pharmaceutical Co., Ltd. 027-59262863 13277907145 QQ:3091977954
027-59420980 dh.luna@whdhwy.com China 4962 58
Shanghai QianJin Chemical Technology Co., Ltd 021-20900665,17321230821
021-20900665 shqjchemical@163.com China 1684 55

View Lastest Price from Diphenoxylate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 Diphenoxylate
915-30-0
US $7.00 / kg 1kg 99% 100kg career henan chemical co

915-30-0(Diphenoxylate)Related Search:


  • DIPHENOXYLATE
  • 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylicacidethylester
  • 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylicaciethyl
  • 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecoticacidethylester
  • 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-isonipecoticaciethylester
  • 2,2-diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile
  • ethyl1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate
  • ethyl1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate
  • 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-isonipecoticacidethylester
  • ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
  • Diphenoxylate hydrochloride CP2000,BP98
  • DiphenoxyleteHCl
  • -
  • 915-30-0
  • C30H32N2O2
  • Diphenoxyletehydrochloride
  • 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
  • Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
  • HYPPXZBJBPSRLK-UHFFFAOYSA-N
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