4-Fluorobenzoic acid
- CAS No.
- 456-22-4
- Chemical Name:
- 4-Fluorobenzoic acid
- Synonyms
- PFBA;P-FLUOROBENZOIC ACID;potassium 2,2,3,3,3-pentafluoropropanoate;4-fluoro-benzoicaci;The acid;AKOS 92636;p-Fluorobenzoic;fluorobenzoicacid;Fluoro benzoic ac;4-Fluorbenzoesure
- CBNumber:
- CB4853637
- Molecular Formula:
- C7H5FO2
- Molecular Weight:
- 140.11
- MDL Number:
- MFCD00002530
- MOL File:
- 456-22-4.mol
- MSDS File:
- SDS
Melting point | 182-184 °C (lit.) |
---|---|
Boiling point | 117 °C |
Density | 1.479 |
storage temp. | Sealed in dry,Room Temperature |
solubility | alcohol: soluble |
form | Crystalline Powder |
pka | 4.15(at 25℃) |
color | White to slightly yellow |
Water Solubility | Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water. |
Merck | 14,4171 |
BRN | 1906922 |
InChIKey | BBYDXOIZLAWGSL-UHFFFAOYSA-N |
CAS DataBase Reference | 456-22-4(CAS DataBase Reference) |
FDA UNII | V5ROO2HOU4 |
NIST Chemistry Reference | Benzoic acid, 4-fluoro-(456-22-4) |
EPA Substance Registry System | Benzoic acid, 4-fluoro- (456-22-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-41-36/37/38 | |||||||||
Safety Statements | 26-39-24/25-22-37/39-36 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29163900 | |||||||||
NFPA 704 |
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4-Fluorobenzoic acid price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 128384 | 4-Fluorobenzoic acid 98% | 456-22-4 | 5g | $17.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 128384 | 4-Fluorobenzoic acid 98% | 456-22-4 | 25g | $35 | 2024-03-01 | Buy |
TCI Chemical | F0112 | 4-Fluorobenzoic Acid >98.0%(GC)(T) | 456-22-4 | 25g | $47 | 2024-03-01 | Buy |
Alfa Aesar | A14129 | 4-Fluorobenzoic acid, 98% | 456-22-4 | 25g | $34.4 | 2024-03-01 | Buy |
Alfa Aesar | A14129 | 4-Fluorobenzoic acid, 98% | 456-22-4 | 100g | $77.65 | 2024-03-01 | Buy |
4-Fluorobenzoic acid Chemical Properties,Uses,Production
Description
4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the 18F labeling of antibodies. It has been used in high resolution charge density study.
Reference
AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356
Chemical Properties
white to light yellow crystal powder
Uses
4-Fluorobenzoic acid has been used in high resolution charge density study.
Definition
ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.
Purification Methods
Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]
4-Fluorobenzoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 723 | 55 |
EAST STAR BIOTECH (SUZHOU) CO., LTD. | +8617706846989 | marketing@eaststarbio.com | China | 48 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6001 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6709 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16799 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15965 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
View Lastest Price from 4-Fluorobenzoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-13 | 4-Fluorobenzoic acid
456-22-4
|
US $15.00 / KG | 1KG | 99% | 300MT/year | Speranza Chemical Co., Ltd. | ||
2024-02-23 | 4-Fluorobenzoic acid
456-22-4
|
US $38.00 / kg | 1kg | 0.99 | 100kg | Shanghai UCHEM Inc. | ||
2024-01-23 | 4-Fluorobenzoic acid
456-22-4
|
US $9.00-0.90 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
- 4-Fluorobenzoic acid
456-22-4
- US $15.00 / KG
- 99%
- Speranza Chemical Co., Ltd.
- 4-Fluorobenzoic acid
456-22-4
- US $38.00 / kg
- 0.99
- Shanghai UCHEM Inc.
- 4-Fluorobenzoic acid
456-22-4
- US $9.00-0.90 / KG
- 99%
- Henan Fengda Chemical Co., Ltd