Azosemide
- CAS No.
- 27589-33-9
- Chemical Name:
- Azosemide
- Synonyms
- Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP
- CBNumber:
- CB5200179
- Molecular Formula:
- C12H11ClN6O2S2
- Molecular Weight:
- 370.84
- MDL Number:
- MFCD00867321
- MOL File:
- 27589-33-9.mol
- MSDS File:
- SDS
Melting point | 218-221° |
---|---|
Boiling point | 221°C (rough estimate) |
Density | 1.6843 (rough estimate) |
refractive index | 1.6100 (estimate) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | 3.58±0.10(Predicted) |
color | Crystals |
CAS DataBase Reference | 27589-33-9(CAS DataBase Reference) |
FDA UNII | MR40VT1L8Z |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302+H312+H332-H315-H319-H227 |
Precautionary statements | P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P235 |
Toxicity | LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87 |
Azosemide price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A965145 | Azosemide | 27589-33-9 | 10g | $845 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0001575 | AZOSEMIDE 95.00% | 27589-33-9 | 100MG | $727.65 | 2021-12-16 | Buy |
AK Scientific | E592 | Azosemide | 27589-33-9 | 100mg | $298 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA44032 | Azosemide | 27589-33-9 | 10mg | $40 | 2021-12-16 | Buy |
ChemScene | CS-0028137 | Azosemide >98.0% | 27589-33-9 | 10mg | $50 | 2021-12-16 | Buy |
Azosemide Chemical Properties,Uses,Production
Description
Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.
Originator
Boehringer Manheim (W. Germany)
Uses
Diuretic.
Uses
Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.
Definition
ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.
Manufacturing Process
The 4-chloro-5-sulfamoyl-2-thenylaminobenzonitrile used as starting material
is obtained by the reaction of 4-chloro-2-fluoro-5-sutfamoyl-benzonitrile with
thenylamine in anhydrous tetrahydrofuran.
Then the 5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)phenyltetrazole (MP 218°
to 221°C, yield 37% of theory) is obtained by the reaction of 4-chloro-5-
sulfamoyl-2-thenylaminobenzonitrite (MP 170° to 174°C) with sodium azide
and ammonium chloride,
brand name
LURET
Therapeutic Function
Diuretic
Safety Profile
Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl-, SOx,and NOx.
Azosemide Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 | sales@tjzxchem.com | China | 562 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | sales@coreychem.com | China | 29914 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12466 | 58 |
Hebei Binshare New Material Co. Ltd | +8618633865755 | china01@hbbinshare.com | CHINA | 969 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
View Lastest Price from Azosemide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-06-14 | Azosemide
27589-33-9
|
US $1.00 / g | 1g | 99% | 300tons | Hebei Dangtong Import and export Co LTD | ||
2024-02-22 | Azosemide
27589-33-9
|
US $1.00 / g | 1g | 99% | 10000kg | Hubei Langyou International Trading Co., Ltd | ||
2023-10-09 | Azosemide
27589-33-9
|
US $50.00 / kg | 1kg | 0.99 | 10000 | Hebei Yanxi Chemical Co., Ltd. |