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(R)-(-)-3-Pyrrolidinol hydrochloride

(R)-(-)-3-Pyrrolidinol hydrochloride structure

CAS No.: 104706-47-0

Chemical Name:: (R)-(-)-3-Pyrrolidinol hydrochloride

Synonyms: (R)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE;(R)-pyrrolidin-3-ol hydrochloride;(S)-3-PYRROLIDINOL HYDROCHLORIDE;(3R)-Pyrrolidin-3-ol hydrochloride;(R)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE;idinoL;CAS:104706-47-0;(R)-(-)-3-PyrroL;TIMTEC-BB SBB004272;(R)-3-Hydroxypyrroli

CBNumber:: CB6125385

Molecular Formula:: C4H10ClNO

Molecular Weight:: 123.58

MDL Number:: MFCD00191570

MOL File:: 104706-47-0.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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(R)-(-)-3-Pyrrolidinol hydrochloride Properties

Melting point	104-107 °C(lit.)
alpha	-7.6°(20/D, c=3,5, CH3OH)
refractive index	-7.8 ° (C=3.5, MeOH)
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in DMSO.
form	Solid
color	Pale Brown
optical activity	[α]20/D 7.6°, c = 3.5 in methanol
BRN	4450078
InChI	InChI=1/C4H9NO.ClH/c6-4-1-2-5-3-4;/h4-6H,1-3H2;1H/t4-;/s3
InChIKey	QPMSJEFZULFYTB-PGMHMLKASA-N
SMILES	[C@H]1(O)CNCC1.Cl \|&1:0,r\|
CAS DataBase Reference	104706-47-0(CAS DataBase Reference)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-41-38-37

Safety Statements

26-36-38

WGK Germany

3-10

HS Code

29339900

NFPA 704

	1
2		1

(R)-(-)-3-Pyrrolidinol hydrochloride price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	430722	(R)-3-Pyrrolidinol hydrochloride 98%	104706-47-0	1G	$45	2024-03-01	Buy
Sigma-Aldrich	430722	(R)-3-Pyrrolidinol hydrochloride 98%	104706-47-0	10g	$162	2024-03-01	Buy
TCI Chemical	P1140	(R)-(-)-3-Pyrrolidinol Hydrochloride >98.0%(T)	104706-47-0	5g	$101	2024-03-01	Buy
TCI Chemical	P1140	(R)-(-)-3-Pyrrolidinol Hydrochloride >98.0%(T)	104706-47-0	25g	$355	2024-03-01	Buy
Alfa Aesar	H52743	(R)-3-Hydroxypyrrolidine hydrochloride, 97%	104706-47-0	1g	$24.5	2023-06-20	Buy

Product number	Packaging	Price	Buy
430722	1G	$45	Buy
430722	10g	$162	Buy
P1140	5g	$101	Buy
P1140	25g	$355	Buy
H52743	1g	$24.5	Buy

(R)-(-)-3-Pyrrolidinol hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Llight brown crystalline

Uses

(R)-3-Pyrrolidinol hydrochloride can be used as a building block to synthesize:

Biaryl carboxamide functional groups containing bis-aminopyrrolidine ureas as potential antagonists of the melanin-concentrating hormone receptor-1.
Pyrrolidinol based ionic liquids.
Optically active 2-tritylpyrrolidine based organocatalysts.

Uses

(R)-(-)-3-Pyrrolidinol hydrochloride is a chiral hydroxy derivative of pyrrlodine used in the preparation of chiral niologically active compounds such as muscarinic receptor antagonists and antimicrobial agents.

Uses

(R)-3-Hydroxypyrrolidine hydrochloride is used as a darifenacin Intermediate.

Purification Methods

The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]

(R)-(-)-3-Pyrrolidinol hydrochloride synthesis

Synthesis of (R)-(-)-3-Pyrrolidinol hydrochloride from (R)-1-Boc-3-hydroxypyrrolidine

(R)-(-)-3-Pyrrolidinol hydrochloride Preparation Products And Raw materials

Raw materials

Ethanol Calcium chloride Acetyl chloride Benzylamine Sodium borohydride

Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Hydrochloric acid Dichloromethane

Cyclohexanol Acetic acid Methanol Sodium hydroxide 2-Cyclohexen-1-one

L-Hydroxyproline PETROLEUM ETHER HEAVY DISTILLATE D(+)-Malic acid

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Preparation Products

(R)-(-)-3-Pyrrolidinol hydrochloride Suppliers

Global( 451)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd	+8618068193575	sales4@btcpharm.com	China	251	58
JiangXi Bobert Imp&Exp Co.,LTD	+8618071643627	rze2024@163.com	China	226	58
SHANGHAI SAGACHEM CO., LTD.	+86-02168404722 +86-13816115801	david_si@shjlchem.com	China	197	58
Hebei Ganmiao New material Technology Co., LTD	+86-17332992504 +86-17332992504	sales8@hbganmiao.com	China	300	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21631	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29865	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2136	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd	58
JiangXi Bobert Imp&Exp Co.,LTD	58
SHANGHAI SAGACHEM CO., LTD.	58
Hebei Ganmiao New material Technology Co., LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from (R)-(-)-3-Pyrrolidinol hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-03-17	(R)-(-)-3-Pyrrolidinol hydrochloride 104706-47-0	US $120.00 / kg	1kg	0.99	1000000	Hebei Fengjia New Material Co., Ltd
2024-08-20	(R)-(-)-3-Pyrrolidinol hydrochloride 104706-47-0	US $10.00-7.00 / kg	1kg	99%	20ton	Hebei Ganmiao New material Technology Co., LTD
2024-02-26	(R)-(-)-3-Pyrrolidinol hydrochloride 104706-47-0	US $0.00-0.00 / kg	1kg	99%	Kgs	BTC Nantong Pharmaceuticals Technology Co.,Ltd

(R)-(-)-3-Pyrrolidinol hydrochloride
104706-47-0
US $120.00 / kg
0.99
Hebei Fengjia New Material Co., Ltd

(R)-(-)-3-Pyrrolidinol hydrochloride
104706-47-0
US $10.00-7.00 / kg
99%
Hebei Ganmiao New material Technology Co., LTD

(R)-(-)-3-Pyrrolidinol hydrochloride
104706-47-0
US $0.00-0.00 / kg
99%
BTC Nantong Pharmaceuticals Technology Co.,Ltd

(R)-(-)-3-Pyrrolidinol hydrochloride Spectrum

(R)-(-)-3-Pyrrolidinol hydrochloride(104706-47-0)MS (R)-(-)-3-Pyrrolidinol hydrochloride(104706-47-0)¹HNMR (R)-(-)-3-Pyrrolidinol hydrochloride(104706-47-0)¹³CNMR (R)-(-)-3-Pyrrolidinol hydrochloride(104706-47-0)IR1 (R)-(-)-3-Pyrrolidinol hydrochloride(104706-47-0)IR2

104706-47-0((R)-(-)-3-Pyrrolidinol hydrochloride)Related Search:

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PYRROLIDONE HYDROTRIBROMIDE N-Methyl-2-pyrrolidone Povidone iodine METHYL-2-PYRROLIDONE Scopine hydrochloride

HYOSCINE HYDROCHLORIDE 3-PYRROLIDINOL HYDROCHLORIDE (S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE,(S)-3-PYRROLIDINOL HYDROCHLORIDE,3-PYRROLIDINOL, HYDROCHLORIDE, (3S),(S)-(+)-3-PYRROLIDINOL HYDROCHLORIDE,98% DL-3-PYRROLIDINOL Darifenacin

3-FURANAMINE, TETRAHYDRO- (R)-3-Hydroxypyrrolidine trans-4-Hydroxy-L-proline methyl ester hydrochloride

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(R)-(-)-3-PYRROLIDINOL HCL (R)-3-Hydroxypyrrolidine hydrochloride, (R)-3-Pyrrolidinol hydrochloride (R)-()-3-Pyrrolidinol hydrochloride ,97% (R)-3-Hydroxypyrroli (3R)-3-Hydroxypyrrolidine hydrochloride (R)-3-Pyrrolindinol hydrochloride (R)-3-AMINOTETRAHYDROFURAN HYDROCHLORIDE TIMTEC-BB SBB004272 (R)-(-)-3-Pyrrolidonol hydrochloride (R)-(-)-3-PYRROLIDINOL HYDROCHLORIDE, 98 % (R)-(-)-3-PYRROLIDINOL HYDROCHLORIDE 98% (R)-3-Hydroxypyrrolidine Hydrochloride (Darifenacin) Product naMe (R)-(-)-3-Pyrrolidinol hydrochloride (R)-pyrrolidin-3-ol HCl 3-Pyrrolidinol,hydrochloride (1:1), (3R) (R)-(-)-3-Pyrrolidinol hydrochloride SynonyMs (R)-3-Hydroxypyrrolidine hydrochloride (R)-(-)-3-Pyrrolidinol hydrochloride (3R)-Pyrrolidin-3-ol, HCl (R)-3-hydroxyp yrrolidine hydrochlorode (R)-Tetrahydrofuran-3-ol hydrochloride (R)-3-Pyrrolidinol Hydrochloride,99%e.e. 3-PYRROLIDINOL, HYDROCHLORIDE, (3R)- 3-PYRROLIDINOL, HYDROCHLORIDE, (3S) 3R-HYDROXYPYROLIDINE HCL 3-FURANAMINE, TETRAHYDRO-, (R)-, HYDROCHLORIDE (S)-PYRROLIDIN-3-OL HCL (S)-PYRROLIDINE-3-OL HYDROCHLORIDE (R)-PYRROLIDINE-3-OL HYDROCHLORIDE (S)-3-HYDROXY PYRROLIDINE HCL (S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE (R)-(-)-3-PYRROLIDINOL HYDROCHLORIDE (R)-(+)-3-PYRROLIDINOL HYDROCHLORIDE (R)-3-PYRROLIDINOL HYDROCHLORIDE (R)-3-HYDROXYPYRROLIDINE HCL (R)-(-)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE (R)-(-)-3-PyrroL idinoL (3R)-3-Pyrrolidinol, hydrochloride (1:1) (R)-(-)-3-PyrrolidinolHydrochloride> (R) - (-) -3-pyrrolidine hydrochloride (R)-(-)-3-Pyrrolidinol hydrochloride ISO 9001：2015 REACH 104706-47-0 (R)-(-)-3-Pyrrolidinol hydrochloride C4H10ClNO (3R)-Pyrrolidin-3-ol hydrochloride (R)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE (R)-pyrrolidin-3-ol hydrochloride (R)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE (S)-3-PYRROLIDINOL HYDROCHLORIDE 104706-47-0 (3R)-3-Pyrrolidinol HCl (3R)-3-Pyrrolidinol hydrochloride CAS:104706-47-0 104706-47-0 C4H10CINO C4H9NOHClC4H10ClNO C4H9NOClH C4H10ClNOC4H9NOHCl Chiral Building Blocks Simple Alcohols (Chiral)