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Arbekacin structure
Chemical Name:
Molecular Formula:
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Arbekacin Properties

CAS DataBase Reference
51025-85-5(CAS DataBase Reference)


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Arbekacin Chemical Properties,Uses,Production


Arbekacin is a semi-synthetic derivative of dibekacin useful in the treatment of bacterial infections. This aminoglycoside is active against a broad spectrum of bacteria, including some of the gentamycin-, kanamycin-, and tobramycin-resistant pathogens. Compared to amikacin and dibekacin, ototoxicity is reportedly milder.


Inst. Microbial Chemistry (Japan)


ChEBI: A kanamycin that is kanamycin B bearing an N-(2S)-4-amino-2-hydroxybutyryl group on the aminocyclitol ring.

brand name


Antimicrobial activity

The 1-N-(4-amino-2-hydroxybutyryl) derivative of dibekacin, to which it bears the same relation as amikacin bears to kanamycin A. Supplied as the sulfate.
Activity and stability to aminoglycoside-modifying enzymes are comparable with those of amikacin. It is active against many strains of methicillin-resistant Staph. aureus, either alone or in combination with β-lactam or other agents. Synergy with ampicillin has been observed for high-level gentamicin- and vancomycin-resistant enterococci.
A 3 mg/kg intravenous dose achieved a peak concentration of c. 8 mg/L after 1 h. The plasma half-life is about 2 h and protein binding 3–12%.
About 85% of the dose can be recovered from urine over 48 h. It is retained in renal failure, but moderately well removed by hemodialysis with a plasma half-life of 2–4 h. Peak concentrations of 10.9 mg/L and trough concentrations of 1.7 mg/L have been reported in patients treated for MRSA infection where Cmax:MIC ratios of >25 and AUC:MIC ratios of >186 were associated with improved cure rates, and both Cmin and AUC were associated with the incidence of nephrotoxicity.
Toxicity and side effects are typical of the aminoglycoside class. It is used in severe infection cause by susceptible microorganisms, but is not widely available.

Arbekacin Preparation Products And Raw materials

Raw materials

Preparation Products

Arbekacin Suppliers

Global( 33)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Shenzhen Enzan Biomedical Co., Ltd. 075525325458 CHINA 58 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725;010-86181995
010-65763397 China 12343 58
(CSR Factory)China Skyrun Industrial CO.,ltd Please Email China 12128 58
China Kouting Group Limited +86 (21) 5811-6473 5811-6475
+86 (21) 6129-4103 China 498 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794
021-61478794 China 9808 50
Credit Asia Chemical Co., Ltd. +86 (21) 61124340
+86 (21) 6129-4103 China 9784 58
Shanghai Synchem Pharma Co., ltd +86-21-61984905 ext 1、ext 2 、+86-18016477331 China 5208 55
Wuhan HongxinKang Fine Chemical Co., Ltd. 18672345876
027-59721024 China 1861 58

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