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Diethyl acetylenedicarboxylate

Diethyl acetylenedicarboxylate structure

CAS No.: 762-21-0

Chemical Name:: Diethyl acetylenedicarboxylate

Synonyms: Diethyl but-2-ynedioate;DIETHYL BUTYNEDIOATE;Diethyl 2-butynedioate;YL2-BUTYNEDIOATE;Diethyl butyrate;Diethyl acetylenedic;Bis(carboethoxy)acetylene;Diethyl but-2-yne-1,4-dioate;Bis-(Ethoxycarbonyl)acetylene;DIETHYL ACETYLENEDICARBOXYLATE

CBNumber:: CB8456726

Molecular Formula:: C8H10O4

Molecular Weight:: 170.16

MDL Number:: MFCD00009186

MOL File:: 762-21-0.mol

MSDS File:: SDS

Last updated:2023-09-01 17:37:15

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Diethyl acetylenedicarboxylate Properties

Melting point	1-3 °C
Boiling point	107-110 °C11 mm Hg(lit.)
Density	1.063 g/mL at 25 °C(lit.)
refractive index	n20/D 1.443(lit.)
Flash point	202 °F
storage temp.	2-8°C
form	Liquid
Specific Gravity	1.063
color	Clear light yellow
Water Solubility	Soluble in ethanol, ethyl ether, CCl4, Insoluble in water.
BRN	743166
CAS DataBase Reference	762-21-0(CAS DataBase Reference)
NIST Chemistry Reference	Diethylacetylene dicarboxylate(762-21-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Hazard Codes

Risk Statements

Safety Statements

26-36/37/39-45-25

RIDADR

UN 3265 8/PG 2

WGK Germany

8-10

HazardClass

PackingGroup

III

HS Code

29171990

NFPA 704

	0
3		0

Diethyl acetylenedicarboxylate price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	159441	Diethyl acetylenedicarboxylate 95%	762-21-0	5g	$49.3	2024-03-01	Buy
Sigma-Aldrich	159441	Diethyl acetylenedicarboxylate 95%	762-21-0	25g	$151	2024-03-01	Buy
TCI Chemical	A0089	Diethyl Acetylenedicarboxylate >96.0%(GC)	762-21-0	25mL	$98	2024-03-01	Buy
TCI Chemical	A0089	Diethyl Acetylenedicarboxylate >96.0%(GC)	762-21-0	250mL	$734	2024-03-01	Buy
Alfa Aesar	A11719	Diethyl acetylenedicarboxylate, 96%	762-21-0	25g	$66.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
159441	5g	$49.3	Buy
159441	25g	$151	Buy
A0089	25mL	$98	Buy
A0089	250mL	$734	Buy
A11719	25g	$66.65	Buy

Diethyl acetylenedicarboxylate Chemical Properties,Uses,Production

Chemical Properties

Diethyl acetylenedicarboxylate is a clear light yellow liquid which has a disagreeable smell. It is a cheap and readily available material in industry. The triple bond is a critical and useful functional group, and it has extensive applications in organic synthesis. It can react with amines, aldehydes, ketones, etc. Therefore it can be used to form various heterocycles.

Synthesis of diethyl acetylenedicarboxylate

Uses

Diethyl acetylenedicarboxylate was used in the synthesis of:

3,4,5-trisubstituted 2(5H)-furanone derivatives
highly functionalized thiazolidinone derivatives
novel cyclic peroxide glucosides
4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction

Uses

Diethyl acetylenedicarboxylate is used as a protein cross-linker. It is also used in the synthesis of 3,4,5-trisubstituted 2(5H)-furanone derivatives, highly functionalized thiazolidinone derivatives, novel cyclic peroxide glucosides and 4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction.

General Description

Diethyl acetylenedicarboxylate is a protein cross-linker.

Purification Methods

Dissolve the ester in *C6H6, wash it with NaHCO3, H2O, dry over Na2SO4, filter, evaporate and distil it in a vacuum [IR: Walton & Hughes J Am Chem Soc 79 3985 1957, Truce & Kruse J Am Chem Soc 81 5372 1959]. [Beilstein 2 H 803.]

Diethyl acetylenedicarboxylate synthesis

Synthesis of Diethyl acetylenedicarboxylate from Ethanol and Acetylenedicarboxylic acid

Diethyl acetylenedicarboxylate Preparation Products And Raw materials

Raw materials

Acetylenedicarboxylic acid monopotassium salt

Preparation Products

ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 3-HYDROXY-5-METHYL-BENZOIC ACID 7-Ethoxycoumarin 8-(4-Methyl-benzoyl)-5-oxo-1,2,3,5-tetrahydro-imidazo[1,2-a]pyridine-7-carboxylic acid ethyl ester 1-(2-fluoro-phenyl)-5-hydroxy-1H-pyrazole-3-carboxylic acid ethyl ester

DIETHYL 5,6-DIPHENYL-3,4-PYRIDAZINEDICARBOXYLATE 2-Morpholin-4-yl-4-phenyl-thiazole-5-carboxylic acid ethyl ester

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Diethyl acetylenedicarboxylate Suppliers

Global( 292)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4242	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Changzhou Ansciep Chemical Co., Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from Diethyl acetylenedicarboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-01	Diethyl acetylenedicarboxylate 762-21-0	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-08-18	Diethyl acetylenedicarboxylate 762-21-0	US $0.00-0.00 / kg	1kg	0.99	50000kg	Hebei Kingfiner Technology Development Co. , Ltd.
2021-05-27	Diethyl acetylenedicarboxylate 762-21-0	US $1.00 / PCS	1KG	99%	10 mt	Hebei Guanlang Biotechnology Co., Ltd.

Diethyl acetylenedicarboxylate
762-21-0
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Diethyl acetylenedicarboxylate
762-21-0
US $0.00-0.00 / kg
0.99
Hebei Kingfiner Technology Development Co. , Ltd.

Diethyl acetylenedicarboxylate
762-21-0
US $1.00 / PCS
99%
Hebei Guanlang Biotechnology Co., Ltd.

Diethyl acetylenedicarboxylate Spectrum

Diethyl acetylenedicarboxylate(762-21-0)MS Diethyl acetylenedicarboxylate(762-21-0)¹HNMR Diethyl acetylenedicarboxylate(762-21-0)¹³CNMR Diethyl acetylenedicarboxylate(762-21-0)IR1 Diethyl acetylenedicarboxylate(762-21-0)IR2 Diethyl acetylenedicarboxylate(762-21-0)Raman

762-21-0(Diethyl acetylenedicarboxylate)Related Search:

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Tris(trimethylsilyl)phosphate Diethyl oxalacetate Diethyl phthalate

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Diethyl acetylenedicarboxylic acid Diethyl acetylenedicarboxylate,97% Diethyl acetylenedic Diethyl acetylenedicarboxylate, 97% 25GR Diethyl acetylenedicarboxylate 95% Diethyl acetylenedicarboxylate, 98%+ Bis-(Ethoxycarbonyl)acetylene butynedioic acid diethyl ester YL2-BUTYNEDIOATE Diethyl but-2-yne-1,4-dioate DIETHYL ACETYLENEDICARBOXYLATE 2-butynedioic acid diethyl ester ACETYLENEDICARBOXYLIC ACID DIETHYL ESTER but-2-ynedioic acid diethyl ester Bis(carboethoxy)acetylene Diethyl Acetylenedicarboxylate > DIETHYL ACETYLENEDICARBOXYLATE FOR SYNTH Diethyl butyrate 2-Butynedioic acid, 1,4-diethyl ester Diethyl acetylenedicarboxylate ISO 9001：2015 REACH Diethyl but-2-ynedioate Diethyl 2-butynedioate DIETHYL BUTYNEDIOATE 762-21-0 CH3CH2O2CCCCO2CH2CH3 C2H5OCOC8801CCOOC2H5 Acetylenes Acetylenic Carboxylic Acids & Their Derivatives Organic Building Blocks Esters Building Blocks Carbonyl Compounds C8 to C9 Aromatic Esters Miscellaneous Acetylenes Acetylenic Carboxylic Acids & Their Derivatives bc0001