1-Phenoxy-2-propanol is a useful synthetic intermediate. It was used in the preparation of acylarylthiocarbamates as nonnucleoside reverse transcriptase inhibitors.
정의
Colorless liquid.Combustible.
일반 설명
1-Phenoxy-2-propanol (PP), a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst. The influence of its anesthetic property on gastropods has been analyzed. Its degradation by microorganisms in different soil types has been investigated.
Safety Profile
Moderately toxic by ingestion and skin contact. Experimental reproductive effects. When heated to decompositionit emits acrid smoke and irritating vapors.
법규
1-Phenoxy-2-propanol (PP) has antibacterial properties and is designated as a sterilizing and preserving agent used in cosmetics and soaps. In Korea, PP comprises up to 1.0% of formulations and is only allowed in products that are washed off after use, and other products are prohibited. European Commission (EC) restricts washing products to 1.0% or less[1].