이소티오시안산메틸에스테르

이소티오시안산메틸에스테르
이소티오시안산메틸에스테르 구조식 이미지
카스 번호:
556-61-6
한글명:
이소티오시안산메틸에스테르
동의어(한글):
메틸아이소싸이오사이아네이트;이소티오시안산메틸;이소티오시안산메틸에스테르;이소티오시안산메틸;메틸 아이소싸이오사이아네이트;메틸티오시아네이트;이소티오시안산 메틸;메틸이소티오시아네이트
상품명:
Methyl isothiocyanate
동의어(영문):
MIT;isothiocyanatomethane;MIC;MENCS;CH3NCS;MITC;MTC;TRK;TRKA;NTRK1
CBNumber:
CB6455336
분자식:
C2H3NS
포뮬러 무게:
73.12
MOL 파일:
556-61-6.mol
MSDS 파일:
SDS

이소티오시안산메틸에스테르 속성

녹는점
30-34 °C(lit.)
끓는 점
117-118 °C(lit.)
밀도
1.069 g/mL at 25 °C(lit.)
증기압
21 mm Hg ( 20 °C)
굴절률
nD37 1.5258
FEMA
4426 | METHYL ISOTHIOCYANATE
인화점
90 °F
저장 조건
2-8°C
용해도
H2O: 약간 용해됨
물리적 상태
저융점 고체
색상
흰색에서 연한 노란색
냄새
프로필렌 글리콜 중 0.01%. 매운 겨자 양 고추 냉이
?? ??
매운 맛
수용성
7.6g/L
감도
Moisture Sensitive
Merck
14,6092
JECFA Number
1884
BRN
605319
안정성
안정적인. 강한 산화제, 알코올, 강염기, 아민과 호환되지 않습니다.
InChIKey
LGDSHSYDSCRFAB-UHFFFAOYSA-N
LogP
1.3 at 20℃
CAS 데이터베이스
556-61-6(CAS DataBase Reference)
NIST
Methane, isothiocyanato-(556-61-6)
EPA
Methyl isothiocyanate (556-61-6)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T,N
위험 카페고리 넘버 23/25-34-43-50/53
안전지침서 36/37-38-45-60-61
유엔번호(UN No.) UN 2477 6.1/PG 1
WGK 독일 3
RTECS 번호 PA9625000
F 고인화성물질 21
TSCA Yes
위험 등급 6.1
포장분류 I
HS 번호 29309090
유해 물질 데이터 556-61-6(Hazardous Substances Data)
독성 LD50 in rats, mice (mg/kg): 220, 110 orally; in rabbits (mg/kg): 33 dermally (Vernot); LD50 s.c. in mice: 0.05 g/kg (Klesse, Lukoschek)
기존화학 물질 KE-21761
유해화학물질 필터링 97-1-228
함량 및 규제정보 물질구분: 유독물질; 혼합물(제품)함량정보: 이소티오시안산 메틸 및 이를 1% 이상 함유한 혼합물
그림문자(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H301 삼키면 유독함 급성 독성 물질 - 경구 구분 3 위험 GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 GHS hazard pictograms P273, P391, P501
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P303+P361+P353 피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
0 0

이소티오시안산메틸에스테르 C화학적 특성, 용도, 생산

개요

Methyl iso thio cyanate is the organo sulfur compound with the formula CH3N = C = S . This low melting colorless solid is a powerful lachrymator. As a precursor to a variety of valuable bioactive compounds, it is the most important organic iso thio cyanate in industry.

화학적 성질

Methyl isothiocyanate is a crystalline solid. Horseradish, acrid odor.

출처

Reported found in horseradish.

용도

Usually used to study the effect of pesticide Metam (methyl isothiocyanate is its active ingredient) in the streamside microbial communities of the upper Sacramento river

정의

ChEBI: An isothiocyanate having a methyl group attached to the nitrogen.

주요 응용

Solutions of MITC are used in agriculture as soil fumigants, mainly for protection against fungi and nematodes.
MITC is a building block for the synthesis of 1,3,4 - thiadiazoles, which are heterocyclic compounds used as herbicides. Commercial products include "Spike", "Ustilan," and "Erbotan." Well known pharmaceuticals prepared using MITC include Zantac and Tagamet.

화학 반응

A characteristic reaction is with amines to give methyl thioureas:
CH3NCS + R2NH → R2NC(S)NHCH3
Other nucleophiles add similarly.

일반 설명

A colorless liquid with a sharp odor. Lethal by inhalation of even small quantities of vapor. Does not have odor warning characteristics at low concentrations. Do not rely on the sense of smell to warn about the presence of vapors. Denser than water. Flash point below 20°F. May cause tearing and irritate the eyes, skin, nose and throat.

공기와 물의 반응

Highly flammable. Methyl isothiocyanate reacts with water to form carbon dioxide and methylamine gases.

반응 프로필

Isocyanates and thioisocyanates, such as Methyl isothiocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Polyurethanes are formed by the condensation reaction of diisocyanates with, for example, ethyl glycol.

위험도

Toxic by ingestion, strong irritant to eyesand skin.

건강위험

Very toxic; probable human oral lethal dose is 50-500 mg/kg, or between 1 teaspoonful and 1 oz. for a 70 kg (150 lb.) person. Highly irritating to skin, mucous membrances, and eyes. Human oral minimum lethal dose: approximately 1 g/kg.

화재위험

(Non-Specific -- Pesticide, Solid, n.o.s.) Methyl isothiocyanate may burn, but does not ignite readily. Fire may produce irritating or poisonous gases. When heated Methyl isothiocyanate emits very dangerous cyanides and sulfur compounds. Do not store below -4F or at elevated temperatures. Keep away from sparks.

Safety

MITC is a dangerous lachrymator as well as being poisonous.

잠재적 노출

It is used as a soil fumigant. A mixture of methyl isothiocyanate and chlorinated C-3 hydrocarbons is used as a soil fumigant for control of weeds, fungi, insects, and nematodes.

환경귀착

Soil. Though no products were reported, the reported half-life in soil is <14 days (Worthing and Hance, 1991).
Chemical/Physical. Emits toxic fumes of nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987).

신진 대사 경로

Methyl isothiocyanate is slowly decomposed in pure water, forming methylamine. It is metabolised in rats to the mercapturate via the glutathione conjugate which serves as a potential source of methyl isothiocyanate. Methyl isothiocyanate is reactive with cellular thiols and amines and its toxicity is associated with these reactions.

운송 방법

UN2477 Methyl isothiocyanate, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Inhalation Hazard Zone B.

비 호환성

Dust may form explosive mixture with air. Reacts with water, releasing carbon dioxide and methylamine gases. Unstable and reactive; sensitive to oxygen and to light. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, alcohols, strong bases, amines, water, heat and cold. Attacks iron, zinc and other metals

폐기물 처리

In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office

이소티오시안산메틸에스테르 준비 용품 및 원자재

원자재

준비 용품


이소티오시안산메틸에스테르 공급 업체

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Hubei xin bonus chemical co. LTD
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Standardpharm Co. Ltd.
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Chongqing Chemdad Co., Ltd
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CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49392 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29824 58

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