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디옥틸 설포숙시네이트 나트륨염

디옥틸 설포숙시네이트 나트륨염
디옥틸 설포숙시네이트 나트륨염 구조식 이미지
카스 번호:
577-11-7
한글명:
디옥틸 설포숙시네이트 나트륨염
동의어(한글):
디옥틸나트륨설포숙신산;디옥틸설포숙시네이트나트륨염;설포부탄다이옥산1,4-비스(2-에틸헥실)에스터나트륨염;다이에틸헥실소듐설포석시네이트;디옥틸나트륨설포숙신산
상품명:
Dioctyl sulfosuccinate sodium salt
동의어(영문):
AOT;DSS;sbo;DOSS;doxol;nevax;revac;sv102;Wetter;colace
CBNumber:
CB7769467
분자식:
C20H37O7S.Na
포뮬러 무게:
444.56
MOL 파일:
577-11-7.mol

디옥틸 설포숙시네이트 나트륨염 속성

녹는점
173-179 °C(lit.)
끓는 점
82.7°C
밀도
1.1
저장 조건
2-8°C
용해도
methanol: 0.1 M at 20 °C, clear, colorless
물리적 상태
Waxy Solid
색상
White
Specific Gravity
1.005_PERCENT VOLATILE: 40
수용성
1.5 g/100 mL (25 ºC)
감도
Hygroscopic
최대 파장(λmax)
λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.05
Merck
14,3401
BRN
4117588
안정성
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS 데이터베이스
577-11-7(CAS DataBase Reference)
EPA
Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl) ester, sodium salt(577-11-7)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,Xi
위험 카페고리 넘버 22-38-41-36/37/38
안전지침서 26-39-37/39-36
WGK 독일 2
RTECS 번호 WN0525000
F 고인화성물질 3-10
TSCA Yes
HS 번호 29171900
유해 물질 데이터 577-11-7(Hazardous Substances Data)
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 P264, P280, P302+P352, P321,P332+P313, P362
H318 눈에 심한 손상을 일으킴 심한 눈 손상 또는 자극성 물질 구분 1 위험 P280, P305+P351+P338, P310
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 P264, P280, P305+P351+P338,P337+P313P
H361 태아 또는 생식능력에 손상을 일으킬 것으로 의심됨 생식독성 물질 구분 2 경고 P201, P202, P281, P308+P313, P405,P501
H362 모유를 먹는 아이에게 유해할 수 있음 생식독성 물질,수유 또는 수유기에 미치는 영향 추가 카테고리 P201, P260, P263, P264, P270,P308+P313
H402 수생생물에 유해함 수생 환경유해성 물질 - 급성 구분 3
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P202 모든 안전 조치 문구를 읽고 이해하기 전에는 취급하지 마시오.
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P263 임신·수유 기간에는 접촉하지 마시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P321 (…) 처치를 하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
P332+P313 피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P405 밀봉하여 저장하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

디옥틸 설포숙시네이트 나트륨염 MSDS


Bis(2-ethylhexyl) sulfosuccinate sodium salt

디옥틸 설포숙시네이트 나트륨염 C화학적 특성, 용도, 생산

화학적 성질

white solid, often supplied as an aqueous solution

화학적 성질

Docusate sodium is a white or almost white, waxlike, bitter tasting, plastic solid with a characteristic octanol-like odor. It is hygroscopic and usually available in the form of pellets, flakes, or rolls of tissuethin material.

용도

dioctyl sodium sulfosuccinate is a mild surfactant used as a cleans ing agent.

용도

Dioctyl sulfosuccinate sodium salt is a wetting and emulsifying agent that is slowly soluble in water, having a solubility of 1 g in 70 ml of water. It functions as a wetting agent in fumaric acid-containing powdered fruit drinks to help the acid dissolve in water. It is used as a stabilizing agent on gums at not more than 0.5% by weight of the gum. It is used as a flavor potentiator in canned milk where it improves and maintains the flavor of the sterilized milk during storage. It also functions as a processing aid in the manufacture of unrefined sugar. It is also termed sodium dioctylsulfosuccinate.

용도

Forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid

용도

anticholinergic, treatment of motion sickness

생산 방법

Maleic anhydride is treated with 2-ethylhexanol to produce dioctyl maleate, which is then reacted with sodium bisulfite.

상표명

Colace (Roberts Pharmaceutical); Correctol Stool Softener Laxative (Schering-Plough HealthCare); Dialose (Johnson & Johnson-Merck Consumer); Doxinate (Hoechst-Roussel); D-S-S (Parke-Davis); Modane Soft (Savage); Molofac (Bristol-Myers Squibb).

일반 설명

Odorless colorless to white waxy solid. Sinks and mixes slowly with water.

공기와 물의 반응

Mixes slowly with water.

반응 프로필

Docusate sodium causes foaming and spreading of water. Assists in putting out fires by water. [USCG, 1999].

건강위험

Liquid is strong irritant to eye and may irritate skin by removing natural oils. Ingestion causes diarrhea and intestinal bloating.

화재위험

Behavior in Fire: Causes foaming and spreading of water. Assists in putting out fires by water.

Pharmaceutical Applications

Docusate sodium and docusate salts are widely used as anionic surfactants in pharmaceutical formulations. Docusate sodium is mainly used in capsule and direct-compression tablet formulations to assist in wetting and dissolution.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. See also ESTERS. When heated to decomposition it emits toxic fumes of SOx and Na2O.

Safety

Docusate salts are used in oral formulations as therapeutic agents for their fecal softening and laxative properties. As a laxative in adults, up to 500mg of docusate sodium is administered daily in divided doses; in children over 6 months old, up to 75 mg in divided doses is used. The quantity of docusate sodium used as an excipient in oral formulations should therefore be controlled to avoid unintended laxative effects. Adverse effects associated with docusate sodium include diarrhea, nausea, vomiting, abdominal cramps, and skin rashes. As with the chronic use of laxatives, the excessive use of docusate sodium may produce hypomagnesemia.
Docusate salts are absorbed from the gastrointestinal tract and excreted in bile; they may cause alteration of the gastrointestinal epithelium. The gastrointestinal or hepatic absorption of other drugs may also be affected by docusate salts, enhancing activity and possibly toxicity. Docusate sodium should not be administered with mineral oil as it may increase the absorption of the oil.
LD50 (mouse, IV): 0.06 g/kg
LD50 (mouse, oral): 2.64 g/kg
LD50 (rat, IP): 0.59 g/kg
LD50 (rat, oral): 1.9 g/kg

저장

Docusate sodium is stable in the solid state when stored at room temperature. Dilute aqueous solutions of docusate sodium between pH 1–10 are stable at room temperature. However, at very low pH (<1) and very high pH (>10) docusate sodium solutions are subject to hydrolysis.
The solid material is hygroscopic and should be stored in an airtight container in a cool, dry place.

Purification Methods

Dissolve it in MeOH and the inorganic salts which precipitate are filtered off. Water is added and the solution is extracted several times with hexane. The residue is evaporated to one-fifth its original volume, *benzene is added and azeotropic distillation is continued until no water remains. The solvent is evaporated. The white residual solid is crushed and dried in vacuo over P2O5 for 48hours [El Seoud & Fendler J Chem Soc, Faraday Trans 1 71 452 1975]. [Beilstein 4 IV 114.] It solubilises major myelin trans membrane proteolipids, and forms reverse micelles in hydrocarbon solvents.

비 호환성

Electrolytes, e.g. 3% sodium chloride, added to aqueous solutions of docusate sodium can cause turbidity. However, docusate sodium possesses greater tolerance to calcium, magnesium, and other polyvalent ions than do some other surfactants. Docusate sodium is incompatible with acids at pH < 1 and with alkalis at pH > 10.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (IM injections; oral capsules, suspensions, and tablets; also topical formulations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

디옥틸 설포숙시네이트 나트륨염 준비 용품 및 원자재

원자재

준비 용품


디옥틸 설포숙시네이트 나트륨염 공급 업체

글로벌( 288)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Hubei xin bonus chemical co. LTD
13657299721
zhangyuzhu@xhlchem.com CHINA 17424 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25796 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23959 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8266 58
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 18981987031
028-84555506 QQ:800101999 cdhxsj@163.com China 9979 58

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