다이아이소프로필아민
|
|
다이아이소프로필아민 속성
- 녹는점
- -61 °C (lit.)
- 끓는 점
- 84 °C (lit.)
- 밀도
- 0.722 g/mL at 25 °C (lit.)
- 증기 밀도
- 3.5 (vs air)
- 증기압
- 50 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.392(lit.)
- 인화점
- 1.4 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 100g/L(20°C)
- 산도 계수 (pKa)
- 11.05(at 25℃)
- 물리적 상태
- 액체
- 색상
- 무색의
- 냄새
- 아민.
- 수소이온지수(pH)
- 11.8 (6g/l, H2O, 20℃)
- 폭발한계
- 1.1-7.1%(V)
- 수용성
- 100g/L(20℃)
- Merck
- 14,3196
- BRN
- 605284
- 노출 한도
- NIOSH REL: TWA 5 ppm (20 mg/m3), IDLH 200 ppm; OSHA PEL: TWA 5 ppm; ACGIH TLV: TWA 5 ppm (adopted).
- Dielectric constant
- 3.04
- 안정성
- 안정적인. 가연성. 강한 산화제와 호환되지 않습니다. 강산이나 산화제와 격렬하게 반응할 수 있음. 공기에 민감합니다.
- InChIKey
- UAOMVDZJSHZZME-UHFFFAOYSA-N
- LogP
- 0.4 at 20℃
- CAS 데이터베이스
- 108-18-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,C | ||
---|---|---|---|
위험 카페고리 넘버 | 11-20/22-34 | ||
안전지침서 | 16-26-36/37/39-45 | ||
유엔번호(UN No.) | UN 1158 3/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | IM4025000 | ||
자연 발화 온도 | 599 °F | ||
위험 참고 사항 | Highly Flammable/Corrosive/Harmful | ||
TSCA | Yes | ||
HS 번호 | 2921 19 99 | ||
위험 등급 | 3 | ||
포장분류 | II | ||
유해 물질 데이터 | 108-18-9(Hazardous Substances Data) | ||
독성 | LD50 orally in rats: 0.77 g/kg (Smyth) | ||
IDLA | 200 ppm | ||
기존화학 물질 | KE-24105 |
다이아이소프로필아민 C화학적 특성, 용도, 생산
개요
Diisopropylamine is a secondary amine and is a colorless liquid at room temperature with a fishy, ammonia-like odor. It is used as a chemical intermediate, and catalyst for the synthesis of pesticides and pharmaceuticals. Diisopropylamine is associated with tobacco either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products. Synonyms for diisopropylamine include DIPA, and N-(1-methylethyl)-2- propanamine.화학적 성질
Diisopropylamine is a flammable, strongly alkaline Colorless liquid. Diisopropylamine is soluble in water and alcohol. The odor threshold ranges from 0.017 to 4.2 ppm; the fishlike odor becomes irritating at 100 mg/m3.물리적 성질
Colorless liquid with an ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 50 μg/m3 (130 ppbv) and 190 μg/m3 (380 ppbv), respectively (Hellman and Small, 1974).주요 응용
Diisopropylamine is used as a solvent and in the chemical synthesis of dyes, pharmaceuticals, and other organic syntheses. It used to synthesize diisopropylamine methyl urea (DMU), N,N-diisopropyl quinoline-2-carboxamide, 3-N-sulfonylamidine coumarins and N-chloroamine, an intermediate to generate amides.일반 설명
Diisopropylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Used to make other chemicals.공기와 물의 반응
Highly flammable. Soluble in water. Sensitive to heat and air.반응 프로필
Diisopropylamine can react violently with oxidizing agents and strong acids. Readily eutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.건강위험
Permitted levels of diisopropylamine should not cause adverse health and welfare effects. Acute inhalation exposure to diisopropylamine can cause sore throat, cough, burning sensation and shortness of breath. Adverse effects occur mainly in the upper respiratory tract, although after chronic exposure. There is no definitive evidence that diisopropylamine causes cancer so a chronic cancer value was not developed. Diisopropylamine has not been classified as causing cancer by the International Agency for Research on Cancer, the United States Environmental Protection Agency, the American Conference of Industrial Hygienists, or the National Toxicology Program.화학 반응
Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.공업 용도
Diisopropylamine is used as a catalyst and as a stabilizer for mesityl oxide (HSDB 1989). It is also used as an intermediate in the synthesis of dyes, pharmaceuticals and pesticides (e.g. Diallate, Fenamiphos and Triallate).Safety Profile
Moderately toxic by ingestion and subcutaneous routes. Mildly toxic by inhalation. Mutation data reported. A skin and severe eye irritant. Inhalation of fumes can cause pulmonary edema. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam,foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx See also AMINES.환경귀착
Photolytic. Low et al. (1991) reported that the photooxidation of aqueous secondary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.Chemical/Physical. Reacts with acids forming water-soluble salts.
신진 대사
Little, if any investigation of the metabolism of short-chain aliphatic amines has been reported and the best that can be done is to suggest some possible metabolic routes. For example the flavin monooxygenase system could produce the hydroxylamine through N-hydroxylation catalyzed by the flavin monooxygenase system (Ziegler 1988). N-hydroxylation can also be induced with the cytochrome P-450 system as can N-dealkylation reactions (Lindeke and Cho 1982). More definitive analysis must await experimental studies.Purification Methods
Distil the amine from NaOH, or reflux it three minutes over Na wire or NaH, and distil it into a dry receiver under N2. [Beilstein 4 H 154, 4 I 369, 4 II 630, 4 III 274, 4 IV 510.]다이아이소프로필아민 준비 용품 및 원자재
원자재
준비 용품
2-Fluoro-6-formylpyridine
4-Pyridyl acetone
4-(트리플루오로메틸)피리딘-3-카복실산
1-(3,4-DICHLOROBENZYL)PIPERAZINE
메틸(2-)헥사논산
1-TERT-BUTYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID
Triallate
DIBENZYL DIISOPROPYLPHOSPHORAMIDITE
BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE
2-Chloro-4-iodopyridine-3-carboxaldehyde
3,4-DIBROMO-5-HYDROXY-5H-FURAN-2-ONE
3-BROMO-4-FORMYLPYRIDINE
2-Fluoro-5-iodobenzaldehyde
5-AMINO-2-METHOXY-3-PICOLINE
디알린산
2-[3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol
1-Boc-4-methylpiperidine-4-carboxylic acid
Eflornithine
2,5-DICHLORO-4-FORMYLPYRIDINE
1-Boc-piperazine acetate
3,4-Dichloropyridine
3-Amino-5-phenylpyrazole
디이소프로필아미노에탄올
2-Bromo-6-fluorobenzoic acid
5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
N,N-DIISOPROPYLBENZOTHIAZOLE-2-SULFENAMIDE
1,2-BIS(4-PYRIDYL)ETHANE
4-BROMO-5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE
1-(2-ISOCYANO-ETHYL)-4-METHYL-PIPERAZINE
2-Chloro-6-trifluoromethylnicotinic acid
2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID
3-FLUOROPYRIDINE-4-BORONIC ACID
2-클로로니코틴산
dichlorodihydroxybis(isopropylamine)platinum
2-(Tributylstannyl)pyrimidine
3-Chloro-4-pyridineboronic acid hydrate
4-AMINO-2-BUTANOL
크레아틴인
4-Chloropyridine-3-carboxaldehyde
Pinacidil
다이아이소프로필아민 공급 업체
글로벌( 416)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ShanDong Look Chemical Co.,Ltd. | +8617653113219 |
sales01@sdlookchemical.com | China | 2739 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Hebei Dangtong Import and export Co LTD | +8615632927689 |
admin@hbdangtong.com | China | 991 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
다이아이소프로필아민 관련 검색:
프로필아민 트리에틸아민 이소프로필아민 디알릴아민 1,3-디이소프로필 카보디아미드 이소프로필술파이드 N-메틸-2-피롤리디논 트리알릴아민 오도라틴 (Odoratine) 이소프로필시클로헥산아민 알릴아민 다이-n-뷰틸아민 N,N-다이아이소프로필에틸아민 2,2,6,6-사메틸-4-피페리디놀 4-옥소-템포, 자유 라디칼 다이아이소프로필아민
Diisopropylammonium dichloroacetate
(1R,3s,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane