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Torasemide

Torasemide Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-571-85586718
Email: sales@capotchem.com
Products Intro: Product Name:N-(isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
CAS:56211-40-6
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Torasemide
CAS:56211-40-6
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:TorseMide(anhydrous)
CAS:56211-40-6
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: PI & PI BIOTECH INC.
Tel: 020-81716320
Email: Sales@pipitech.com
Products Intro: Product Name:Torasemide
CAS:56211-40-6
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:1-(1-Methylethyl)-3-[[4-[(3-methylphenyl)amino]pyridin-3-yl]sulfonyl]urea
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail:sales03@shyrchem.com
Email: sales03@shyrchem.com
Products Intro: Product Name:Torasemide
CAS:56211-40-6
Purity:99% Package:100g;500g;1kg;25kg...

Lastest Price from Torasemide manufacturers

  • torasemide
  • US $1.00 / Kg/Drum
  • 2019-07-18
  • CAS:56211-40-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 9999tons
  • Torasemide
  • US $1.00 / KG
  • 2019-07-06
  • CAS:56211-40-6
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100kg
Torasemide Basic information
Diuretics Uses
Product Name:Torasemide
Synonyms:n-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfo;TORASEMIDE,TORSEMIDE;TorsemideUsp2598-102%;N-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonylmethanamide;N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide, AC-4464, BM-02015, JDL-464, Demadex, Luplac, Toradiur, Torem, Torasemide.;TORASEMIDE(SUBJECTTOPATENTFREE);3-Pyridinsulfonamid, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-;Unat
CAS:56211-40-6
MF:C16H20N4O3S
MW:348.42
EINECS:637-197-3
Product Categories:Active Pharmaceutical Ingredients;Diuretic;APIs;Torasemide;All Inhibitors;Inhibitors;ANTIZOL;Intermediates & Fine Chemicals;Pharmaceuticals;Ion transporter and other ion channel
Mol File:56211-40-6.mol
Torasemide Structure
Torasemide Chemical Properties
Melting point 163-164°C
density 1.283±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO: soluble18mg/mL
form solid
pka6.44(at 25℃)
Water Solubility Soluble
Merck 14,9552
InChIKeyNGBFQHCMQULJNZ-UHFFFAOYSA-N
CAS DataBase Reference56211-40-6(CAS DataBase Reference)
EPA Substance Registry System3-Pyridinesulfonamide, N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]- (56211-40-6)
Safety Information
Hazard Codes Xi
Risk Statements 36-36/37/38
Safety Statements 26-37/39
WGK Germany 2
RTECS UT7938000
HS Code 2935904000
MSDS Information
ProviderLanguage
Torasemide English
Torasemide Usage And Synthesis
DiureticsDiuretics are drugs mainly acting on the kidneys to increase the excretion of water and electrolytes, and increase urine output. Their potency can be divided into:
1. potent diuretics (loop diuretics): including furosemide, bumetanide, ethacrynic acid.
2. Middle efficiency diuretics include: thiazide diuretics, such as hydrochlorothiazide, bendroflumethiazide and so on.
3. Inefficient diuretics include: retention of potassium diuretics spironolactone, triamterene and carbonic anhydrase inhibitor acetazolamide and the like.
Potent diuretics effect on medullary loop ramus crude segment medulla,they inhibit reabsorption of active chlorine, followed by inhibiting sodium reabsorption, and play a strong diuretic effect.
Torasemide is a potent diuretic, its mechanism of action is similar to furosemide, it has no effect on the proximal tubules, it does not cause an increase in the discharge of potassium. This product increase renal volume and sodium excretion is dose-dependent , it does not affect the calcium and potassium excretion, excretion and metabolism have no association with renal function, large doses have no significant toxicity. Sort diuretic strength by: bumetanide> torasemide> piretanide> furosemide. It is useful in the treatment of acute and chronic renal failure and essential hypertension. Adverse reactions of torasemide are similar to furosemide ,common adverse reactions are headache, dizziness, weakness, nausea, muscle spasms, but it produces lesser extent of potassium loss ,it has no effect on uric acid, blood glucose and lipid .
The above information is edited by the chemicalbook of Tian Ye.
UsesIt is used as a diuretic.
DescriptionTorasemide is a novel loop diuretic launched in 1993 after a 12-year gap from the last diuretic introduction. It is indicated for the treatment of hypertension and edema associated with chronic congestive heart failure, renal disease and hepatic cirrhosis. Torasemide exerts its major diuretic activity on the thick ascending limb of the Henle's loop to promote rapid and marked excretion of water, Na+, Cl-, and to a lesser extent,K+ and Ca2+. Compared with other loop diuretics such as furosemide, torasemide has a stronger antihypertensive action, a higher bioavailability, a longer duration of action that is independent of the renal function, and has no side effects such as paradoxical antidiuresis. The mechanism of its vasodilating effect has been suggested to result from, at least in part, the competitive antagonism of the thromboxane A2 receptor.
Chemical PropertiesCrystalline Solid
OriginatorHafslund Nycomed Germany; Italy (Norway)
Usesalcohol dehydrogenase inhibitor, antidote
UsesUsed as a diuretic
DefinitionChEBI: An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea.
Brand nameTorasemide is INN and BAN;Unat;Toradiur.
Torasemide Preparation Products And Raw materials
Tag:Torasemide(56211-40-6) Related Product Information
TORASEMIDE FOR SYSTEM SUITABILITY TORSEMIDE RELATED COMPOUND B (75 MG) (N-[(N-BUTYLAMINO)CARBONYL]-4-[(3-METHYLPHENYL)A-MINO]-3-PYRIDINESULFONAMIDE) TORASEMIDE ANHYDROUS Torasemide1,4-Dihydroxy-2-Butyne 4-Amino-3-pyridinesulfonamide ISO-PROPYL-D7-AMINE Torasemide intermediate,4-(3-methylphenyl)amino-3-pyridine sulfonamide (intermediate of torasemide) Torasemide p-Toluenesulfonamide GRANULAR UREA 3-Aminobenzenesulfonamide Sulfuryl chloride Benzenesulfonamide 3-Aminopyridine Urea 4-Dimethylaminopyridine Semicarbazide 2-Aminopyridine