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Biperiden hydrochloride

Biperiden hydrochloride Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86 (0)571-855 867 18
Products Intro: Product Name:Biperiden hydrochloride
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Biochempartner
Tel: 0086-13720134139
Products Intro: Product Name:Biperiden HCl
Purity:98% HPLC LCMS Package:10G;20G
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Products Intro: CAS:1235-82-1
Purity:99% Package:5KG;1KG;25KG PRICE quotation Remarks:Factory stock, quality assurance, price concessions
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
Products Intro: Product Name:Biperiden Hydrochloride (Mixture of DiastereoMers)
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 86-21-50328103 * 801、802、803、804 Mobile:18930552037
Products Intro: Product Name:Biperiden hydrochloride;α-Bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanolhydrochloride
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Biperiden hydrochloride Basic information
Product Name:Biperiden hydrochloride
Synonyms:akinetonhydrochloride;alpha-(bicyclo(2.2.1)hept-5-en-2-yl)-alpha-phenyl-1-piperidinepropanolhydroc;alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanohydrochloride;alpha-5-norbornen-2-yl-alpha-phenyl-piperidinepropanolhydrochloride;biperidinehydrochloride;BIPERIDEN HYDROCHLORIDE;BIPERIDINE HCL;Biperidene hydrochloride
Product Categories:Acetylcholine receptor;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Akineton;Inhibitors
Mol File:1235-82-1.mol
Biperiden hydrochloride Structure
Biperiden hydrochloride Chemical Properties
Melting point 238°
storage temp. Desiccate at +4°C
solubility DMSO: >20mg/mL
form powder
color off-white
NIST Chemistry ReferenceAkineton, hydrochloride(1235-82-1)
Safety Information
Hazard Codes Xn
Risk Statements 22-R22
WGK Germany 3
RTECS TN3706000
ToxicityLD50 in rats, dogs (mg/kg): 750, 340 orally (Hanna)
MSDS Information
Biperiden hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA muscarinic receptor antagonist
UsesBiperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.
DefinitionChEBI: The hydrochloride salt of biperiden. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.
Brand nameAkineton (Abbott).
General DescriptionBiperiden hydrochloride,α-5-norbornen-2-yl- -phenyl-1-piperidinepropanolhydrochloride (Akineton hydrochloride), is a white, opticallyinactive, crystalline, odorless powder that is slightlysoluble in water, ether, alcohol, and chloroform and sparinglysoluble in methanol.
Biological ActivityMuscarinic receptor antagonist that displays some selectivity for the M 1 subtype (K i values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M 1 , M 4 , M 3 , M 2 and M 5 receptors respectively). Alleviates extrapyramidal symptoms associated with antipsychotic drugs. Displays antiparkinsonian activity.
Clinical UseBiperiden hydrochloride has all of the actions describedfor biperiden. The hydrochloride is used for tablets becauseit is better suited to this dosage form than is the lactate salt.As with the free base and the lactate salt, xerostomia (drynessof the mouth) and blurred vision may occur.
Biperiden hydrochloride Preparation Products And Raw materials
Tag:Biperiden hydrochloride(1235-82-1) Related Product Information
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