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Sulfapyridine

Sulfapyridine Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Sulfapyridine
CAS:144-83-2
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:144-83-2
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Sulfapyridine
CAS:144-83-2
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Email: chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com
Products Intro: CAS:144-83-2
Purity:99% Package:5KG;1KG;25KG PRICE quotation Remarks:Factory stock, quality assurance, price concessions
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
Email: export@haihangchem.com
Products Intro: Product Name:Sulfapyridine
CAS:144-83-2

Lastest Price from Sulfapyridine manufacturers

  • Sulfapyridine
  • US $8.00 / kg
  • 2019-05-13
  • CAS:144-83-2
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10MT
Sulfapyridine Basic information
Product Name:Sulfapyridine
Synonyms:n(sup1)-2-pyridyl-sulfanilamid;n(sup1)-2-pyridylsulfanilamide;N(Sup1)-Pyridylsulfanilamide;N’-2-Pyridylsulfanilamide;N1-2-Pyridylsulfanilamide;N-2-pyridinylsulfanilamide;N-2-Pyridylsulfanilamide;Piridazol
CAS:144-83-2
MF:C11H11N3O2S
MW:249.29
EINECS:205-642-7
Product Categories:Pharmaceuticals;Sulfapyridine;SULPHAPYRIDINE;Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds;Intermediates & Fine Chemicals
Mol File:144-83-2.mol
Sulfapyridine Structure
Sulfapyridine Chemical Properties
Melting point 191-193°C
density 1.3220 (rough estimate)
refractive index 1.6740 (estimate)
storage temp. 2-8°C
pkapKa 8.48(H2O t = 25 I = 0.05) (Uncertain)
form neat
Water Solubility <0.1 g/100 mL at 22 ºC
Merck 14,8938
BRN 222065
Stability:Stable. Combustible. Protect from light. Incompatible with strong oxidizing agents.
CAS DataBase Reference144-83-2(CAS DataBase Reference)
NIST Chemistry ReferenceSulfapyridine(144-83-2)
EPA Substance Registry SystemBenzenesulfonamide, 4-amino-N-2-pyridinyl-(144-83-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 2
RTECS DA9625000
HazardClass IRRITANT
ToxicityLD50 orally in mice: 7.5 mg/g (Wien)
MSDS Information
ProviderLanguage
4-((2-Pyridylamino)sulfonyl)aniline English
SigmaAldrich English
Sulfapyridine Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesUsed in treatment of dermatitis herpetiformis; antibacterial.
Usesantibacterial, dermatitis herpetiformis therapy
DefinitionChEBI: A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position.
General DescriptionOdorless or almost odorless white or yellowish-white crystalline powder. Very slightly bitter taste. Aqueous solution is neutral.
General DescriptionSulfapyridine’s plasma half-life is 9 hours.This compound is a white, crystalline, odorless, and tastelesssubstance. It is stable in air but slowly darkens on exposureto light. It is soluble in water (1:3,500), in alcohol(1:440), and in acetone (1:65) at 25°C. It is freely soluble indilute mineral acids and aqueous solutions of sodium andpotassium hydroxide. The pKa is 8.4. Its outstanding effectin curing pneumonia was first recognized by Whitby; however,because of its relatively high toxicity, it has been supplantedlargely by sulfadiazine and sulfamerazine. Severalcases of kidney damage have resulted from acetylsulfapyridinecrystals deposited in the kidneys. It also causes severenausea in most patients. Because of its toxicity, it is usedonly for dermatitis herpetiformis.
Sulfapyridine was the first drug to have an outstandingcurative action on pneumonia. It gave impetus to the studyof the whole class of N1 heterocyclically substituted derivativesof sulfanilamide.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileSulfapyridine is an amino acid. Slowly darkens on exposure to light . Soluble in both acidic and basic aqueous solutions
Fire HazardFlash point data for Sulfapyridine are not available; however, Sulfapyridine is probably combustible.
Safety ProfileModerately toxic by intraperitoneal and intravenous routes. Slightly toxic by ingestion. Experimental reproductive effects. Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NO, and SOx.
Purification MethodsCrystallise sulfapyridine from 90% acetone and dry it at 90o. Its solubility in Me2CO, EtOH and H2O is 1.5%, 0.22% and 0.02%, respectively. [Winterbottom J Am Chem Soc 62 160 1940, Beilstein 22 III/IV 3978.]
Sulfapyridine Preparation Products And Raw materials
Preparation ProductsSalicylazosulfapyridine
Raw materials2-Aminopyridine
Tag:Sulfapyridine(144-83-2) Related Product Information
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