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67-64-1

67-64-1 Structure

67-64-1 Structure
IdentificationMore
[Name]

Acetone
[CAS]

67-64-1
[Synonyms]

ACETONE ALCOHOL
GRAMS DECOLORIZER
GRAM STAIN NO 3
(CH3)2CO
2-Propanon
aceton
aceton(german,dutch,polish)
Acetone oil
ai3-01238
beta-Ketopropane
caswellno.004
Chevron acetone
chevronacetone
Dimethylformaldehyde
Dimethylketal
epapesticidechemicalcode004101
Ketone propane
Ketone, dimethyl-
ketone,dimethyl
ketonepropane
[EINECS(EC#)]

200-662-2
[Molecular Formula]

C3H6O
[MDL Number]

MFCD00211536
[Molecular Weight]

58.08
[MOL File]

67-64-1.mol
Chemical PropertiesBack Directory
[Appearance]

Acetone is a highly flammable, colorless liquid with a sweet, mint-like odor
[Appearance]

Colorless liquid
[mp ]

-94 °C(lit.)
[bp ]

56 °C760 mm Hg(lit.)
[density ]

0.791 g/mL at 25 °C(lit.)
[vapor density ]

2 (vs air)
[vapor pressure ]

184 mm Hg ( 20 °C)
[FEMA ]

3326
[refractive index ]

n20/D 1.359(lit.)
[Fp ]

1 °F
[storage temp. ]

Store at RT.
[Water Solubility ]

soluble
[Merck ]

14,66
[BRN ]

63580
[Uses]

acetone is a solvent considered to be non-comedogenic and occasionally used in skin toners. It is primarily used in nail polish remover. It could be drying and very irritating to the skin depending on the concentration and frequency of use.
[CAS DataBase Reference]

67-64-1(CAS DataBase Reference)
[NIST Chemistry Reference]

Acetone(67-64-1)
[EPA Substance Registry System]

67-64-1(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

F,Xi,T
[Risk Statements ]

R11:Highly Flammable.
R36:Irritating to the eyes.
R66:Repeated exposure may cause skin dryness or cracking.
R67:Vapors may cause drowsiness and dizziness.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S9:Keep container in a well-ventilated place .
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
[RIDADR ]

UN 1090 3/PG 2
[WGK Germany ]

3
[RTECS ]

AL3150000
[F ]

3-10
[HazardClass ]

3
[PackingGroup ]

II
[HS Code ]

29141100
[Safety Profile]

Moderately toxic by various routes. A skin and severe eye irritant. Human systemic effects by inhalation: changes in EEG, changes in carbohydrate metabolism, nasal effects, conjunctiva irritation, respiratory system effects, nausea and vomiting, and muscle weakness. Human systemic effects by ingestion: coma, kidney damage, and metabolic changes. Narcotic in high concentration. In industry, no injurious effects have been reported other than skin irritation resulting from its defatting action, or headache from prolonged inhalation. Experimental reproductive effects. A common air contaminant. Highly flammable liquid. Dangerous disaster hazard due to fire and explosion hazard; can react vigorously with oxidizing materials. Potentially explosive reaction with nitric acid + sulfuric acid, bromine trifluoride, nitrosyl chloride + platinum, nitrosyl perchlorate, chromyl chloride, thiotrithiazyl perchlorate, and (2,4,6-trichloro-l,3,5triazine + water). Reacts to form explosive peroxide products with 2-methyl-1,3butadiene, hydrogen peroxide, and peroxomonosulfuric acid. Ignites on contact with activated carbon, chromium trioxide, dioxygen difluoride + carbon dioxide, and potassium-tert-butoxide. Reacts violently with bromoform, chloroform + alkalies, bromine, and sulfur dichloride. Incompatible with CrO, (nitric + acetic acid), NOCl, nitryl perchlorate, permonosulfuric acid, NaOBr, (sulfuric acid + potassium dichromate), (tho-diglycol + hydrogen peroxide), trichloromelamine, air, HNO3, chloroform, and H2SO4. To fight fire, use Con, dry chemical, alcohol foam. Used in production of drugs of abuse
[Hazardous Substances Data]

67-64-1(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Benzene-->tert-Butanol-->PROPYLENE-->Acetic acid calcium salt-->2-Amino-3-chlorobenzoic acid-->PETROLEUM ETHER-->4-Isopropyltoluene-->CUMENE-->DIISOPROPYLBENZENE-->ZINC CHROMATE-->Cumyl hydroperoxide-->PYROLIGNEOUS ACID-->Lng
[Preparation Products]

Pyridazin-3-amine-->2-BROMODODECANOIC ACID-->3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-CARBALDEHYDE-->2,5-Dichlorothiophene-3-sulfonamide-->Dimethyl acetylmethylphosphonate-->3-(-Hydroxyphenethyl)-2-imino thiazolidine-->3-Methyl butynol -->Iodoform-->PROPIONAMIDINE-->2-(4-BENZYLOXYPHENYL)ETHANOL-->7-Methoxycoumarin-->7-ALLYLOXYCOUMARIN-->9,9-dimethylcarbazine-->5-METHOXY-2-METHYLINDOLE-->2-Iodoacetamide-->7-ETHOXYCOUMARIN-->Ethoxyquin-->4-CARBOXYPHENYL ISOTHIOCYANATE-->2-(MORPHOLINE-4-CARBONYL)-BENZOIC ACID-->CHEMBRDG-BB 6088138-->L(-)-Epinephrine-->CINCHOPHEN-->3-DIMETHYLAMINOPROPIOPHENONE HYDROCHLORIDE-->methyl 3,4-dihydro-4-oxoquinazoline-7-carboxylate-->3-Methyl-2-thiophenecarboxylic acid-->1,1,3,3-TETRABROMOACETONE-->PYRIDINE-2-SULFONIC ACID-->Orciprenaline-->2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE-->4-(2-THIENYL)BUT-3-EN-2-ONE-->Amikacin sulfate salt-->H-GLU-LYS-OH-->Isophorone-->Amikacin disulfate salt -->Divinyltetramethyldisiloxane-->4-Hydroxybenzylideneacetone-->1-Phenylethanone phenylhydrazone-->CHALCONE-->Pentaerythritol tetranitrate-->3,3',4,4'-Benzophenonetetracarboxylic dianhydride
Hazard InformationBack Directory
[General Description]

A clear colorless liquid with a sweetish odor. Flash point 0°F. Less dense than water. Vapors are heavier than air. Used as a solvent in paint and nail polish removers.
[Reactivity Profile]

ACETONE was reported that a mixture of ACETONE(67-64-1) and chloroform, in a residue bottle, exploded. Since addition of ACETONE(67-64-1) to chloroform in the presence of base will result in a highly exothermic reaction, ACETONE(67-64-1) is thought that a base was in the bottle [MCA Case History 1661. 1970]. Also, Nitrosyl chloride, sealed in a tube with a residue of ACETONE(67-64-1) in the presence of platinum catalyst, gave an explosive reaction [Chem. Eng. News 35(43):60. 1967]. The reaction of nitrosyl perchlorate and ACETONE(67-64-1) ignites and explodes. Explosions occur with mixtures of nitrosyl perchlorate and primary amine [Ann. Chem. 42:2031. 1909]. Reacts violently with nitric acid. Also causes exothermic reaction when in contact with aldehydes.
[Air & Water Reactions]

Highly flammable. Water soluble.
[Health Hazard]

INHALATION: vapor irritating to eyes and mucous membranes; acts as an anesthetic in very high concentrations. INGESTION: low order of toxicity but very irritating to mucous membranes. SKIN: prolonged excessive contact causes defatting of the skin, possibly leading to dermatitis.
[Potential Exposure]

It is used as a solvent in nail polish remover and many other chemicals. Used in the production of lubricating oils and as an intermediate in the manufacture of chloroform and of various pharmaceuticals and pesticides.
[Fire Hazard]

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once, and irrigate immediately with large amounts of water for at least 15 minutes. If this chemical contacts the skin, quickly remove contaminated clothing, and wash with large amounts of soap immediately. If a person breathes in large amounts of this chemical, move the exposed person to fresh air at once, and perform (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.
[Shipping]

UN1090 Acetone, Hazard Class: 3; Labels: 3-Flammable liquid
[Incompatibilities]

May explode when mixed with chloroform, chromic anhydride. Incompatible with acids, bases, and oxidizing materials, such as peroxides, chlorates, perchlorates, nitrates, and permanganates. Unstable peroxides formed with strong oxidizers. May accumulate static electrical charges and may cause ignition of its vapors. Dissolves most rubber, resins, and plastics.
[Waste Disposal]

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incineration.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Acetone(67-64-1).msds
Questions And AnswerBack Directory
[Introduction]

Acetone (also known as propanone, dimethyl ketone, 2-propanone, propan-2-one and β-ketopropane) is the simplest representative of the group of chemical compounds known as ketones. It is a colorless, volatile, flammable liquid.
Acetone is miscible with water and serves as an important laboratory solvent for cleaning purposes. Acetone is a highly effective solvent for many organic compounds such as Methanol, ethanol, ether, chloroform, pyridine, etc., and is the active ingredient in nail polish remover. It is also used to make various plastics, fibers, drugs, and other chemicals.
Acetone
Acetone exists in nature in the Free State. In the plants, it mainly exists in essential oils, such as tea oil, rosin essential oil, citrus oil, etc.; human urine and blood and animal urine, marine animal tissue and body fluids contain a small amount of acetone.
[Uses]

  • An important organic raw material in the chemical, artificial fiber, medicine, paint, plastics, organic glass, cosmetics and other industries; an excellent organic solvent that dissolves many organic products such as resin, cellulose acetate, acetylene and so on.
  • An important raw material for the synthesis of ketene, acetic anhydride, iodoform, polyisoprene rubber, methacrylic acid, methyl ester, chloroform, and epoxy resins.
  • The acetone cyanohydrin obtained from the reaction of acetone with hydrocyanic acid is the raw material of methacrylic resin (perspex).
  • A raw material in the production of epoxy resin intermediate bisphenol A.
  • In pharmaceuticals, acetone is used as extractants for a variety of vitamins and hormones in addition to vitamin C, and dewaxing solvents for petroleum refining.
  • A raw material for nail polish remover in cosmetics
  • One of the raw materials for synthesizing pyrethroids in pesticide industry
  • Acetone is often used to wipe the black ink above the copper tube in the precision copper tube industry.
[Production]

In 1913, the United Kingdom developed a method for fermenting cereals to produce acetone and butanol. In 1920, the dehydrogenation of isopropanol (synthesized by hydration of propylene) appeared. From 1953 to 1955, the United States Hercules and the British Distilling Company jointly developed the cumene process method, thereafter, Japan, the United Kingdom, and the Netherlands also developed other methods. Now, Most of the worldwide industrial production of acetone (and phenol) is based on the cumene process, which uses benzene and propylene as raw materials, via cumene intermediates, then oxidized, hydrolyzed to produce acetone and co-produced phenol.

Acetone is mainly used as an organic solvent and methyl methacrylate (the main raw material for organic glass).In the United States and Western Europe, the two accounts for 70% of the total consumption. It is used for bisphenol A, accounting for 10% to 15%, and the others 15% % to 20%.
[Health Effects]

Summary: Acetone is mainly responsible for the inhibition and anesthesia of the central nervous system and exposure to high concentrations may cause liver, kidney, and pancreas impair to particular people. Because of its low toxicity, rapid metabolism and detoxification, acute poisoning under production conditions is rare. In case acute poisoning happens, symptoms of vomiting, shortness of breath, paralysis, and even coma can occur. After oral administration, burning sensation in the lips and throat may occur after hours of incubation, such as dry mouth, vomiting, drowsiness, acidity and ketosis, and even temporary disturbance of consciousness. The long-term damage of acetone to the human body is manifested as irritation to the eyes such as tearing, photophobia and infiltration of the corneal epithelium, as well as dizziness, burning sensation, throat irritation, and coughing.

Metabolism in the body: After being absorbed by the lungs, gastrointestinal tract, and skin, acetone is easily absorbed into the bloodstream due to its high water solubility and is rapidly distributed throughout the body. The excretion depends on the dose. When the dose is large, the main tract is mainly through the lungs and kidneys, and a very small amount is discharged through the skin. When the dose is small, most of them are oxidized into carbon dioxide. The biological half-life of acetone in blood is 5.3 h for rats, 11 h for dogs, and 3 h for humans. The metabolites of acetone in the human body are mostly a tricarboxylic acid cycle intermediate that is decomposed to acetoacetate and converted to glycogen.
Spectrum DetailBack Directory
[Spectrum Detail]

Acetone(67-64-1) 13C NMR
Acetone(67-64-1) 1H NMR
Acetone(67-64-1) IR1
Acetone(67-64-1) Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Acetone,forHPLC,99.8%(67-64-1)
[Alfa Aesar]

Acetone, Spectrophotometric Grade, 99.5+%(67-64-1)
[Sigma Aldrich]

67-64-1(sigmaaldrich)
67-64-1 suppliers list
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