Sodium acetate trihydrate

Sodium acetate trihydrate Struktur
6131-90-4
CAS-Nr.
6131-90-4
Englisch Name:
Sodium acetate trihydrate
Synonyma:
NaAc;SODA CAUSTIC;Sodium acetate crystal;SODIUM ACETATE 3H2O;SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS)SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS)SODIUM ACETATE, TRIHYDRATE, REAGENT (ACS);lnkM;abs9264;Plasmafusin;Thomaegelin;Natrii acetas
CBNumber:
CB3410262
Summenformel:
C2H9NaO5
Molgewicht:
136.08
MOL-Datei:
6131-90-4.mol

Sodium acetate trihydrate Eigenschaften

Schmelzpunkt:
58 °C
Siedepunkt:
>400°C
Dichte
1,45 g/cm3
Flammpunkt:
>250°C
storage temp. 
Store at +5°C to +30°C.
Löslichkeit
H2O: 3 M at 20 °C, clear, colorless
Aggregatzustand
Solid
Farbe
White
PH
7.5-9.0 (25℃, 50mg/mL in H2O)
pka
4.76 (acetic acid)(at 25℃)
Geruch (Odor)
Slight acetic acid
Säure-Base-Indikators(pH-Indikatoren)
8.5 - 10 at 408 g/l at 25 °C
Wasserlöslichkeit
762 g/L (20 ºC)
maximale Wellenlänge (λmax)
λ: 260 nm Amax: ≤0.01
λ: 280 nm Amax: ≤0.01
Merck 
14,8571
BRN 
3732037
Stabilität:
Stable. Incompatible with strong oxidizing agents, halogens.
InChIKey
AYRVGWHSXIMRAB-UHFFFAOYSA-M
CAS Datenbank
6131-90-4(CAS DataBase Reference)
NIST chemische Informationen
Sodium acetate trihydrate(6131-90-4)
EPA chemische Informationen
Acetic acid, sodium salt, trihydrate (6131-90-4)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 24/25-36-26
WGK Germany  1
RTECS-Nr. AJ4580000
Selbstentzündungstemperatur 607 °C
TSCA  Yes
HS Code  29152200
Toxizität LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg

Sodium acetate trihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

Sodium acetate trihydrate is the trihydrate sodium salt oaf acetic acid. It is a colorless, odorless crystals that can be weathered in the air. Soluble in water and ether, pH of 0.1M aqueous solution is 8.9. moderately soluble in ethanol, 5.3 g/100mL. Anhydrous Sodium acetate occurs as colorless, transparent crystals or a granular crystalline powder with a slight acetic acid odor.

Verwenden

Sodium acetate trihydrate is used in various applications. It is used as a buffer of a pH range in between to 4.0 to 6.0. It is also used in the purification and precipitation of nucleic acids and in protein crystallization. It is used as a mordant dyeing, as a pickling agent in chrome tanning, as a neutralizer in waste streams containing sulfuric acid, in the textile industry and as a photoresist while using aniline dyes. It plays an important role to retard vulcanization of chloroprene in synthetic rubber production. It is a precursor to prepare ester from alkyl halide. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution.

synthetische

Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate.
NaOH + CH3COOH → CH3COONa + H2O
Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O

Allgemeine Beschreibung

Sodium acetate trihydrate can be obtained from the crystallization of sodium acetate in water. On heating at 75°C, it melts, while on heating above 120°C it loses water of crystallization and gets converted into anhydrous form. The hyperfine proton and 13C splittings have been evaluated by recording ESR spectra of its irradiated single crystals. ESR studies suggested the existence of trapped methyl radicals. Its crystals are monoclinic and its crystal structure has been investigated by photographic methods. Unit cell parameters were evaluated.

Pharmazeutische Anwendungen

Sodium acetate is used as part of a buffer system when combined with acetic acid in various intramuscular, intravenous, topical, ophthalmic, nasal, oral, otic, and subcutaneous formulations. It may be used to reduce the bitterness of oral pharmaceuticals. It can be used to enhance the antimicrobial properties of formulations; it has been shown to inhibit the growth of S. aureus and E. coli, but not C. albicans in protein hydrolysate solutions. It is widely used in the food industry as a preservative. Sodium acetate has also been used therapeutically for the treatment of metabolic acidosis in premature infants, and in hemodialysis solutions.

Sicherheit(Safety)

Sodium acetate is widely used in cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material.
A short-term feeding study in chickens with a diet supplemented with 5.44% sodium acetate showed reduced growth rates that were attributed to the sodium content.(9) Sodium acetate is poisonous if injected intravenously, is moderately toxic by ingestion, and is an irritant to the skin and eyes.
LD50 (rat, oral): 3.53 g/kg
LD50 (mouse, IV): 0.38 g/kg
LD50 (mouse, SC): 8.0 g/kg

Lager

Sodium acetate should be stored in airtight containers.

Inkompatibilitäten

Sodium acetate reacts with acidic and basic components. It will react violently with fluorine, potassium nitrate, and diketene.

Regulatory Status

GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections, nasal, otic, ophthalmic, and oral preparations).

Einzelnachweise

[1] http://www.europlat.org
[2] http://www.rxlist.com/sodium-acetate-drug.htm
[3] http://cosmetics.specialchem.com
[4] http://cecri.csircentral.net/2710/1/036-96.pdf

Sodium acetate trihydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sodium acetate trihydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 624)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 +86-19930503282
alice@crovellbio.com China 6489 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
+8618652417778
sales3257@jskolod.com China 129 60
Jiangsu Boquan Biotechnology Co., Ltd.
+undefined18168774353
69925581@qq.com China 92 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21975 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714
fandachem@gmail.com China 9361 55
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418679
info@tnjchem.com China 2990 55
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29922 58
HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
+86-19933070948 +86-19930599843
claire@hbyingong.com China 959 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
linda@hubeijusheng.com CHINA 28185 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845
sales@amoychem.com China 6387 58

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