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Calciumpantothenat , D-Form Produkt Beschreibung

D-(+)-Pantothenic acid calcium salt Struktur
137-08-6
CAS-Nr.
137-08-6
Bezeichnung:
Calciumpantothenat , D-Form
Englisch Name:
D-(+)-Pantothenic acid calcium salt
Synonyma:
pancal;Calpan;(theta)-;Pantholin;NSC 36292;calpanate;VITAMIN B5;panthoject;DL-Calcium;VITAMIN B3/B5
CBNumber:
CB3695335
Summenformel:
C18H32CaN2O10
Molgewicht:
476.53
MOL-Datei:
137-08-6.mol

Calciumpantothenat , D-Form Eigenschaften

Schmelzpunkt:
190 °C
alpha 
26.5 º (c=5, in water)
Brechungsindex
27 ° (C=5, H2O)
Flammpunkt:
145 °C
storage temp. 
2-8°C
Löslichkeit
H2O: 50 mg/mL at 25 °C, clear, nearly colorless
Aggregatzustand
Powder
Farbe
White or almost white
PH
6.8-7.2 (25℃, 50mg/mL in H2O)
Optische Aktivität
[α]20/D +27±2°, c = 5% in H2O
Wasserlöslichkeit
Soluble in water.
Sensitive 
Hygroscopic
Merck 
14,7015
BRN 
3769272
Stabilität:
Stable, but may be moisture or air sensitive. Incompatible with strong acids, strong bases.
InChIKey
FAPWYRCQGJNNSJ-UBKPKTQASA-L
CAS Datenbank
137-08-6(CAS DataBase Reference)
EPA chemische Informationen
Calcium pantothenate (137-08-6)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 20/21/22-37/38-41-48
S-Sätze: 24/25-45-36/37/39-26-22
WGK Germany  1
RTECS-Nr. RU4375000
3-10
TSCA  Yes
HS Code  29362400
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Calciumpantothenat , D-Form Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S22:Staub nicht einatmen.

Chemische Eigenschaften

D-(+)-Pantothenic acid calcium salt is white crystalline powder

Verwenden

D-(+)-Pantothenic acid calcium salt is a member of the B complex vitamins; essential vitamin for the biosynthesis of coenzyme A in mammalian cells. Occurs ubiquitously in all animal and plant tissue. The richest common source is liver, but jelly of the queen bee contains 6 times as much as liver. Rice bran and molasses are other good sources.

Verwenden

calcium pantothenate is used as an emollient and to enrich creams and lotions in hair care preparations. This is the calcium salt of pantothenic acid found in liver, rice, bran, and molasses. It is also found in large amounts in royal jelly.

Verwenden

Calcium Pantothenate is a nutrient and dietary supplement which is the calcium chloride double salt of . It is a white powder of bitter taste and has a solubility of 1 g in 3 ml of water. It is used in special dietary foods.

Trademarks

Calpan (BASF); Pantholin (Lilly).

Allgemeine Beschreibung

The first suggestion for the existance of vitamin B5 came from Carter et al. in 1930; although it was never characterized or isolated. This vitamin is synthesized by most green plants and microorganisms. Excellent sources of the vitamin are liver, egg yolk, whole grains, and fortified ready-to-eat cereals. However, as the original name implies, many foods contain sufficient pantothenic acid to supply dietary needs.
Chemically, pantothenic acid is considered to be aβ-alanine derivative of the asymmetric pantoic acid and thus shows asymmetry. Only the naturally occurring D(+)- stereoisomer (with R configuration) is biologically active and the L(-)-stereoisomer (with S configuration) is inactive. When its carboxylate functional group is attached through an amide linkage with β-mercaptoethylamine, it is known as pantetheine (also spelled pantotheine). The biologically active form of pantothenic acid, CoA, is formed when the terminal alcoholic function of pantetheine is attached to ADP 3'-phosphate.

Clinical Use

The only therapeutic indication for pantothenic acid is intreatment of a known or suspected deficiency of this vitamin.Because of the ubiquitous nature of pantothenic acid, deficiencystates of this vitamin are only seen experimentally byuse of synthetic diets devoid of the vitamin, by use of thevitamin antagonist, ω-methylpantothenic, or both. In a 1991review, Tahiliani and Beinlich described that the mostcommon symptoms associated with pantothenic acid deficiencywere headache, fatigue, and a sensation of weakness.Sleep disturbances and gastrointestinal disturbances, amongothers, were also noted. The most likely setting for pantothenicacid deficiency is in the setting of alcoholism wherea multiple vitamin deficiency exists confounding the exactrole of the pantothenic acid deficiency as compared to theother vitamins. Because a deficiency of a single B vitamin israre, pantothenic acid is commonly formulated in multivitaminor B-complex preparations.

Sicherheitsprofil

Moderately toxic by intraperitoneal, subcutaneous, and intravenous routes. Mildly toxic by ingestion. A vitamin. See also CALCIUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx.

läuterung methode

The salt crystallises as needles from MeOH, EtOH or isoPrOH (with 0.5mol of isoPrOH). It is moderately hygroscopic. The S-benzylisothiuronium salt has m 151-152o (149o when crystallised from Me2CO). [Kagan et al. J Am Chem Soc 79 3545 1957, Wilson et al. J Am Chem Soc 76 5177 1954, Stiller & Wiley J Am Chem Soc 63 1239 1941, Beilstein 4 IV 2569.]

Calciumpantothenat , D-Form Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Calciumpantothenat , D-Form Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 379)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Jiangyin Ligang 2nd Chemical Co., Ltd. 0510-86631396
0510-86638684 82871124@qq.com China 8 60
Nanjing Jinhao Pharmaceutical Co., Ltd. 13382796873;13376086365;15851804510
025-58602884 hjz8008@163.com China 47 58
Ningbo biermann pharmaceutical technology co., LTD 0571-82572971
sunzuqian@bichem.cn China 41 58
Tianjin Zhongxin Chemtech Co., Ltd. 022-66880623;022-89880623
86(0)22-66880086 sales@tjzxchem.com;sales@tjzxchem.com China 579 60
J & K SCIENTIFIC LTD. 010-82848833- ;010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96505 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 21-61259100-
86-21-61259102 sh@meryer.com China 40268 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24555 81
BeiJing Hwrk Chemicals Limted 21-51691807-
021-55236763 peter.shi@hwrkchemical.com; China 18708 55
Energy Chemical 021-58432009
021-58436166-800 sales8178@energy-chemical.com China 44026 61
Adamas Reagent, Ltd. 400-600-9262
bxy@titansci.com China 13918 59

137-08-6(Calciumpantothenat , D-Form)Verwandte Suche:


  • (+)-PANTOTHENIC ACID CALCIUM SALT
  • PANTOTHENIC ACID CALCIUM SALT
  • (R)-(+)-N-(2,4-DIHYDROXY-3,3-DIMETHYL-1-OXOBUTYL)-BETA-ALANINE HEMICALCIUM SALT
  • VITAMIN B5
  • VITAMIN B3/B5
  • (theta)-
  • beta-alanine,n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,calciumsalt(2:1),
  • N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,calciumsalt(2:1),(R)-.beta.-Alanine
  • N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-alaninecalciumsalt
  • n-(2,4-dihydroxy-3,3-dimethylbutyryl)-beta-alaninecalcium
  • pancal
  • panthoject
  • Pantholin
  • .beta.-Alanine, N-(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl-, calcium salt (2:1)
  • D-CALCIUM PANTOTHENATE USP
  • CALCIUMPANTOTHENATE,FCC
  • CALCIUMPANTOTHENATE,POWDER,USP
  • CALCIUMPANTOTHENATE,ULTRAPURE
  • Calcium D-(+)-N-(α,γ-dihydroxy-β,β-dimethylbutyryl)-β-alaninate
  • Calcium, bis(pantothenato)- (7CI)
  • Calpan
  • N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-b-alanine calcium
  • NSC 36292
  • Pantothenic acid hemicalcium salt
  • Pantothenic acid, calcium salt (2:1), D- (8CI)
  • Vitamin B5 calcium salt
  • β-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-
  • β-Alanine, N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-, calcium salt (2:1)
  • Calcium-D-pantothenat
  • CALCIUMPANTOTHENAT
  • (R)-.beta.-Alanine
  • N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt
  • (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-b-alanine hemicalcium salt
  • CALCIUM PANTOTHENATE pure
  • D-Pantothenic acid hemicalcium salt, Calcium D-pantothenate, VitaminB5, (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt
  • CalciuM 3-(2,4-dihydroxy-3,3-diMethylbutanaMido)propanoate
  • CalciuM (R)-3-(2,4-dihydroxy-3,3-diMethylbutanaMido)propanoate
  • CalciuM D-pantothenatealanine heMicalciuM salt
  • d-calcium pantothanate
  • Calcium D-Panthotenate
  • Pantothenic Acid/pantothenate/vitamin B5
  • D-Calcium Panthotenate(Vitamin B5)
  • CALCIUM (+)-PANTOTHENATE
  • CALCIUM PANTOTHENATE
  • CALCIUM D-(+)-PANTOTHENATE
  • CALCIUM D-PANTOTHENATE
  • CALCIUM DEXTRO-ANTOTHENATE
  • D-CALCIUM PANTATHENATE
  • D-CALCIUM PANTHOTENA
  • D-(+)-CALCIUM PANTOTHENATE
  • D-CALCIUM PANTOTHENATE
  • D-VITAMIN B CALCIUM SALT
  • D-PANTOTHENIC ACID, CALCIUM
  • D-PANTOTHENIC ACID CALCIUM SALT
  • D(+)-PANTOTHENIC ACID HEMICALCIUM SALT
  • -Cypermethrin 1-Epimeric Mixture
  • -Cypermethrin-d5 1-Epimeric Mixture
  • Calcium pantothenate (Vitamin B5
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