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2-Thiophenecarboxylic acid

CAS No.
527-72-0
Chemical Name:
2-Thiophenecarboxylic acid
Synonyms
THIOPHENE-2-CARBOXYLIC ACID;thiophene-2-carboxylate;2-THENOIC ACID;2-TCA;THENOIC ACID;AKOS B022791;2-Thenoesure;2-THIOPHENIC ACID;AKOS BBS-00003739;2-Carboxythiophene
CBNumber:
CB1778926
Molecular Formula:
C5H4O2S
Molecular Weight:
128.15
MDL Number:
MFCD00005437
MOL File:
527-72-0.mol
MSDS File:
SDS
Modify Date:2022-12-21 16:56:50

2-Thiophenecarboxylic acid Properties

Melting point 125-127 °C(lit.)
Boiling point 260 °C(lit.)
Density 1.42
refractive index 1.5160 (estimate)
Flash point 259-261°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Acetone (Slightly), Chloroform (Slightly)
form solid
pka 3.49(at 25℃)
color White to Off-White
Water Solubility 80 g/L (20 ºC)
Merck 14,9354
BRN 110150
InChIKey QERYCTSHXKAMIS-UHFFFAOYSA-N
CAS DataBase Reference 527-72-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 3FD00JX53J
NIST Chemistry Reference 2-Thiophenecarboxylic acid(527-72-0)
EPA Substance Registry System 2-Thiophenecarboxylic acid (527-72-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  XM8330200
Hazard Note  Irritant
TSCA  Yes
HS Code  29349990
NFPA 704
0
2 0

2-Thiophenecarboxylic acid price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T32603 2-Thiophenecarboxylic acid ReagentPlus , 99% 527-72-0 25g $37 2023-01-07 Buy
Sigma-Aldrich T32603 2-Thiophenecarboxylic acid ReagentPlus , 99% 527-72-0 100g $78.4 2023-01-07 Buy
TCI Chemical T0218 2-Thiophenecarboxylic Acid >98.0%(T) 527-72-0 25g $55 2023-01-07 Buy
TCI Chemical T0218 2-Thiophenecarboxylic Acid >98.0%(T) 527-72-0 100g $165 2023-01-07 Buy
Alfa Aesar A12514 Thiophene-2-carboxylic acid, 99% 527-72-0 25g $20.6 2021-12-16 Buy
Product number Packaging Price Buy
T32603 25g $37 Buy
T32603 100g $78.4 Buy
T0218 25g $55 Buy
T0218 100g $165 Buy
A12514 25g $20.6 Buy

2-Thiophenecarboxylic acid Chemical Properties,Uses,Production

Uses

2-Thenoic Acid, is a sulfur-containing heterocyclic compound, used in the synthesis of pharmaceutical and biologically active compounds. It is also shown to be utilized by presumptive Rhodococcus bacterium in soil, as a sole source of carbon.

Chemical Properties

white to light yellow crystal powder

Uses

2-Thenoic Acid, is a sulfur-containing heterocyclic compound, used in the synthesis of pharmaceutical and biologically active compounds. It is also shown to be utilized by presumptive Rhodococcus bacterium in soil, as a sole source of carbon.

Definition

ChEBI: A thiophenecarboxylic acid in which the carboxy group is located at position 2.

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 3520, 1965 DOI: 10.1021/jo01021a055

Purification Methods

Crystallise the acid from water and dry it in a vacuum. The amide has m 181o(from H2O) and pK2 5 10.54(50% aqueous dioxane). [Beilstein 18 H 289, 18 I 438, 18 II 269, 18 III/IV 4011, 18/6 V 158.]

636-72-6
527-72-0
Synthesis of 2-Thiophenecarboxylic acid from 2-Thiophenemethanol
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View Lastest Price from 2-Thiophenecarboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Thiophenecarboxylic acid     pictures 2023-03-06 2-Thiophenecarboxylic acid
527-72-0
US $1.90 / KG 1KG 99% 10 ton Hebei Crovell Biotech Co Ltd
2-Thiophenecarboxylic acid pictures 2023-02-10 2-Thiophenecarboxylic acid
527-72-0
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
2-Thiophenecarboxylic acid pictures 2023-01-31 2-Thiophenecarboxylic acid
527-72-0
US $0.00 / Kg/Drum 1Kg/Drum 99% 5000KG Hebei Mojin Biotechnology Co., Ltd
2-Thenoic Acid 2-Thiophenic Acid Thiophene-2-carboxylic acid LABOTEST-BB LT02016392 AKOS B022791 AKOS BBS-00003739 ALPHA-THENOIC ACID 2-THIOPHENIC ACID 2-THIOPHENECARBOXYLIC ACID RARECHEM AL BO 0213 TIMTEC-BB SBB004241 THENOIC ACID 2-Carboxythiophene 2-TCA 2-thienylcarboxylicacid alpha-Thiophenecarboxylic acid alpha-thiophenecarboxylicacid α-thiophenecarboxylicacid Thiophene-2-carboxylicacid,99% 2-Thiophenecarboxylic 2-thiophenezoic acid Thiophene-2-carboxylic acid 97% 2 - Thiophene Carboxilic Acid Thiophene-2-carboxylic acid ,98% 2-Thiophenecarboxylic acid,99% 2-Thiophenecarboxylic acid, 99% 100GR 2-Thiophenecarboxyli 2-Thiophenecarboxylic Acid 2-Thiophenic Acid Thiophenecarboxylic aci 2-Carboxythiophene, 2-Thenoic acid 2-Thiophenecarboxylic acid ReagentPlus(R), 99% 2 - thiophene forMic acid 2-Thiophenecarboxylic acid Vetec(TM) reagent grade, 98% Rivaroxaban Impurity 33 2-Thiophenecaroxylic Acid Thiophen-2-carboxylic acid Rivaroxaban Impurity O Thiophene-2-carboxyL 2-Thiophenecarboxylic acid  Rivaroxaban Impurity 17 2-Thenoic Acid > 2-Thenoesure 2-thiophenoic acid 2-Thiophenecarboxylic acid ISO 9001:2015 REACH 2-Thiophencarboxylic acid Thiophene-2-Carboxylic Acid pure, 98% 2-THENOIC ACID THIOPHENE-2-CARBOXYLIC ACID thiophene-2-carboxylate hiophene-2-carboxylicaci 2-Thiophenecarboxylic acid (6CI, 7CI, 8CI, 9CI, ACI) 527-72-0 C4H3SCOOH ARYL ACID Heterocyclic Building Blocks Building Blocks Thiophenes Miscellaneous Building Blocks Heterocyclic Building Blocks