Imidapril
- CAS No.
- 89371-37-9
- Chemical Name:
- Imidapril
- Synonyms
- IMIDAPRIL;lmidaprfil;Imidapril HCl;Imidapril Hyd;Imidapril-d5 HCl;(S,S,S)-Imidapril;Imidapril USP/EP/BP;IMidapril (Tanatril);(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
- CBNumber:
- CB1780943
- Molecular Formula:
- C20H27N3O6
- Molecular Weight:
- 405.44
- MDL Number:
- MFCD00870777
- MOL File:
- 89371-37-9.mol
Melting point | 195-197°C |
---|---|
alpha | D20 -71.7° (c = 0.5 in ethanol) |
Boiling point | 577.0±60.0 °C(Predicted) |
Density | 1.266±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
pka | 2.44±0.20(Predicted) |
CAS DataBase Reference | 89371-37-9(CAS DataBase Reference) |
FDA UNII | BW7H1TJS22 |
ATC code | C09AA16 |
Imidapril price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0006470 | IMIDAPRIL 95.00% | 89371-37-9 | 10MG | $191.1 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006470 | IMIDAPRIL 95.00% | 89371-37-9 | 100MG | $1593.9 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 11104 | ImidaprilHCl | 89371-37-9 | 50mg | $1880 | 2021-12-16 | Buy |
AvaChem | 1689B | Imidapril | 89371-37-9 | 10mg | $59 | 2021-12-16 | Buy |
AvaChem | 1689B | Imidapril | 89371-37-9 | 25mg | $119 | 2021-12-16 | Buy |
Imidapril Chemical Properties,Uses,Production
Description
Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at a considerably lower dose than enalapril. This stroke preventive effect has been suggested to be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.
Chemical Properties
White Solid
Originator
Tanabe (Japan)
Uses
Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive
Definition
ChEBI: Imidapril is a member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a dipeptide, a member of imidazolidines, a dicarboxylic acid monoester, a secondary amino compound, an ethyl ester and a N-acylurea.
brand name
Tanatril; Novarok
Imidapril Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 878 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5988 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
View Lastest Price from Imidapril manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-10-20 | Imidapril
89371-37-9
|
US $15.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. | ||
2021-10-19 | Imidapril Hydrochloride
89371-37-9
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2021-08-11 | Imidapril USP/EP/BP
89371-37-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
- Imidapril
89371-37-9
- US $15.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.
- Imidapril Hydrochloride
89371-37-9
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- Imidapril USP/EP/BP
89371-37-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
89371-37-9(Imidapril)Related Search:
1of4