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Chemical Name:
TD;TMED;TEMED;TMEDA;Tetrameen;propamined;Toyocat TE;Propamine D;Dabco TMEDA;Kaolizer 11
Molecular Formula:
Formula Weight:
MOL File:

N,N,N',N'-Tetramethylethylenediamine Properties

Melting point:
−55 °C(lit.)
Boiling point:
120-122 °C(lit.)
0.775 g/mL at 20 °C(lit.)
vapor pressure 
21 hPa (20 °C)
refractive index 
n20/D 1.4179(lit.)
Flash point:
50 °F
storage temp. 
Store at RT.
H2O: 10 mg/mL at 20 °C, clear, colorless
10.40, 8.26(at 25℃)
Specific Gravity
0.777 (20/4℃)
Clear colorless to slightly yellow
8.0-8.5 (0.1g/l, H2O, 20℃)
explosive limit
Water Solubility 
Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury.
CAS DataBase Reference
110-18-9(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Ethanediamine, N,N,N',N'-tetramethyl-(110-18-9)
EPA Substance Registry System
1,2-Ethanediamine, N,N,N',N'-tetramethyl- (110-18-9)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F,C,Xi
Risk Statements  11-20/22-34-20/21/22
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2372 3/PG 2
WGK Germany  1
RTECS  KV7175000
Autoignition Temperature 145 °C
Hazard Note  Irritant
HazardClass  3
PackingGroup  II
HS Code  29212900
Hazardous Substances Data 110-18-9(Hazardous Substances Data)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

N,N,N',N'-Tetramethylethylenediamine price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 411019 N,N,N′,N′-Tetramethylethylenediamine ≥99.5%, purified by redistillation 110-18-9 1l $401 2018-11-13 Buy
Sigma-Aldrich 411019 N,N,N′,N′-Tetramethylethylenediamine ≥99.5%, purified by redistillation 110-18-9 2l $700 2018-11-13 Buy
TCI Chemical T0147 N,N,N',N'-Tetramethylethylenediamine >98.0%(GC)(T) 110-18-9 25mL $14 2018-11-22 Buy
TCI Chemical T0147 N,N,N',N'-Tetramethylethylenediamine >98.0%(GC)(T) 110-18-9 100mL $26 2018-11-22 Buy
Alfa Aesar A12536 N,N,N',N'-Tetramethylethylenediamine, 99% 110-18-9 100ml $28.2 2018-11-13 Buy

N,N,N',N'-Tetramethylethylenediamine Chemical Properties,Uses,Production

Chemical Properties

Colorless to slightly yellow liquid


N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.


anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance


ChEBI: An ethylenediamine derivative in which each nitrogen carries two methyl substituents. It is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.


Polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.

General Description

A water-white colored liquid with a fishlike odor. Flash point 68°F. Less dense than water. Vapors heavier than air. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Slightly soluble in water. Sensitive to heat and may be sensitive to air .

Reactivity Profile

N,N,N',N'-Tetramethylethylenediamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by ingestion. Mddly toxic by slun contact. A skin and severe eye irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes of NOx. See also MINES.

Purification Methods

Dry TMEDA partially with molecular sieves (Linde type 4A), then distil it in a vacuum from butyl lithium. This treatment removes all traces of primary and secondary amines and water. [Hay et al. J Chem Soc, Faraday Trans 1 68 1 1972.] Or dry it with KOH pellets, reflux for 2hours with one-sixth its weight of n-butyric anhydride (to remove primary and secondary amines) and fractionally distil it. Reflux it with fresh KOH, and distil it under nitrogen. [Cram & Wilson J Am Chem Soc 85 1245 1963.] It was also distilled from Na. Store it sealed under N2. The dipicrate has m 263o(dec). [Beilstein 4 H 250, 4 I 415, 4 II 690, 4 III 512, 4 IV 1172.]

N,N,N',N'-Tetramethylethylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

N,N,N',N'-Tetramethylethylenediamine Suppliers

Global( 345)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-66880086 CHINA 559 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715 CHINA 2515 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4529 58
career henan chemical co
+86-371-86658258 CHINA 19990 58
Liyang Ruipu New Materials Co., Ltd. 0519-82038123 18951201333
0519-87015112 China 9977 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939
021-51821727 China 15820 55
Shanghai Kangtuo Chemical Co., Ltd. 021-69185553 69185552
021-69186006 China 5176 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 China 25106 65
Shanghai BaiShun Biological Technology Co., Ltd 021-37581181
021-57456066 China 10382 58

View Lastest Price from N,N,N',N'-Tetramethylethylenediamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-18 N,N,N',N'-Tetramethylethylenediamine
US $1.00 / kg 1kg 99% Customized career henan chemical co

N,N,N',N'-Tetramethylethylenediamine Spectrum

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