ChemicalBook
Chinese Japanese Germany Korea

Orthoboric acid

Description References
Orthoboric acid
Orthoboric acid structure
CAS No.
10043-35-3
Chemical Name:
Orthoboric acid
Synonyms
boric;H3-BO3;Borofax;Boracic;Borsure;Ant flip;basilitb;Borsaure;fleaprufe;Entimaden
CBNumber:
CB6128144
Molecular Formula:
BH3O3
Formula Weight:
61.83
MOL File:
10043-35-3.mol

Orthoboric acid Properties

Melting point:
169 °C
Boiling point:
219-220 °C (9.7513 mmHg)
Density 
1.435
vapor pressure 
2.6 mm Hg ( 20 °C)
storage temp. 
Store at RT.
solubility 
H2O: soluble
pka
8.91±0.43(Predicted)
form 
working solution
Specific Gravity
1.435
color 
≤10(APHA)
Odor
Odorless
PH
3.6-4.4 (25℃, saturated solution in H2O)
PH Range
3.8 - 4.8
Water Solubility 
49.5 g/L (20 ºC)
λmax
λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
Sensitive 
Hygroscopic
Merck 
14,1336
BRN 
1697939
InChIKey
KGBXLFKZBHKPEV-UHFFFAOYSA-N
CAS DataBase Reference
10043-35-3(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
BORIC ACID
NIST Chemistry Reference
B(OH)3(10043-35-3)
EPA Substance Registry System
Orthoboric acid (10043-35-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H303-H360-H360FD
Precautionary statements  P201-P308+P313-P280
Hazard Codes  Xi,T,Xn
Risk Statements  36/37/38-60-63-62-61
Safety Statements  26-36-53-45-37/39-36/37/39-22-24/25-23
WGK Germany  2
RTECS  ED4550000
3
TSCA  Yes
HS Code  28100090
Toxicity LD50 orally in rats: 5.14 g/kg (Smyth).

Orthoboric acid price More Price(93)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T7527 Tris-Borate-EDTA buffer BioReagent, for molecular biology, 5x concentrate, DNase and RNase, none detected, powder blend, suitable for electrophoresis 1 L $22.5 2021-03-22 Buy
Sigma-Aldrich T7527 Tris-Borate-EDTA buffer BioReagent, for molecular biology, 5x concentrate, DNase and RNase, none detected, powder blend, suitable for electrophoresis 4 L $57.1 2021-03-22 Buy
Sigma-Aldrich 11607 Boric acid puriss., meets analytical specification of Ph. Eur., BP, NF, 99.5-100.5%, powder 10043-35-3 1kg $72.9 2020-08-18 Buy
Sigma-Aldrich T9525 Tris-Borate-EDTA buffer working solution 1 gal $105 2021-03-22 Buy
Sigma-Aldrich 1076341 Boric acid United States Pharmacopeia (USP) Reference Standard 10043-35-3 1g $475 2020-08-18 Buy

Orthoboric acid Chemical Properties,Uses,Production

Description

Boric acid (orthoboric acid) is a weakly acidic hydrate of boric oxide with mild antiseptic, antifungal, and antiviral properties.
Boric acid can be used to treat yeast infections and acne, for eyewash by treating any bacterial infection and soothing inflamed eyes, and as a cleanser, deodorizer, stain remover, disinfectant and mold killer. Boric acid can be used as a pesticide to control a variety of pests, as a fungicide for citrus, and as an herbicide along rights-of-way. Boric acid can be used for the manufacture of textile fiberglass, household glass products and the glass used in LCD displays, to reinforce plastics in various products (boats, computer circuit boards and pipes), as a flame retardant, and as a pH buffer agent in plating.

References

[1] http://npic.orst.edu
[2] https://www.polyu.edu.hk
[3] Zenat A. Nagieb, Mona A. Nassar, Magda G. El-Meligy (2011) Effect of Addition of Boric Acid and Borax on Fire-Retardant and Mechanical Properties of Urea Formaldehyde Saw Dust Composites, International Journal of Carbonhydrate Chemistry, 2011, 146763
[4] http://www.boricacid.net.au/uses-of-boric-acid

Chemical Properties

White powder or granules and odorless. It is incompatible with potassium, acetic anhydride, alkalis, carbonates, and hydroxides. Boric acid has uses in the production of textile fiberglass, flat panel displays, and eye drops. Boric acid is recognized for its application as a pH buffer and as a moderate antiseptic agent and emulsifier.

Chemical Properties

Boric acid is a white, amorphous powder or colorless, crystalline solid.

Chemical Properties

Boric acid occurs as a hygroscopic, white crystalline powder, colorless shiny plates, or white crystals.

Physical properties

Colorless, transparent triclinic crystal or white granule or powder; density 1.435 g/cm3; melts at 171°C under normal heating; however, slow heating causes loss of water; sparingly soluble in cold water (4.7% at 20°C); pH of 0.1M solution 5.1; readily dissolves in hot water (19.1% at 80°C and 27.5% at 100°C); also soluble in lower alcohols and moderately soluble in pyridine.

Uses

For weatherproofing wood and fireproofing fabrics; as a preservative; manufacture of cements, crockery, porcelain, enamels, glass, borates, leather, carpets, hats, soaps, artificial gems; in nickeling baths; cosmetics; printing and dyeing, painting; photography; for impregnating wicks; electric condensers; hardening steel. Also used as insecticide for cockroaches and black carpet beetles.

Preparation

Boric acid is produced from borax, colemanite, or other inorganic borates by reaction with sulfuric acid or hydrochloric acid, and cooling the solution to proper temperature:
Na2B4O7 ? 10Η2Ο + H2SO4 → 4H3BO3 + Na2SO4 + 5H2O
It also may be prepared by extraction of weak borax brine with a kerosene solution of an aromatic diol, such as 2-ethyl-1,3-hexanediol or 3-chloro- 2-hydroxy-5-(1,1,3,3-tetramethylbutyl)benzyl alcohol. The diol-borate chelate formed separates into a kerosene phase. Treatment with sulfuric acid yields boric acid which partitions into aqueous phase and is purified by recrystallization.

Production Methods

Boric acid occurs naturally as the mineral sassolite. However, the majority of boric acid is produced by reacting inorganic borates with sulfuric acid in an aqueous medium. Sodium borate and partially refined calcium borate (colemanite) are the principal raw materials. When boric acid is made from colemanite, the fineground ore is vigorously stirred with mother liquor and sulfuric acid at about 908℃. The by-product calcium sulfate is removed by filtration, and the boric acid is crystallized by cooling the filtrate.

brand name

Alpagelle;Anojel;Anugard;Anojel;Anugard;Anusol hc;Anusol hc;Berlicetin;Betadrin;Berlicetin;Betadrin;Bluboro;Boroformal;Bluboro;Boroformal;Borogal;Borogal;Borsyre viskos;Cacimag;Borsyre viskos;Cacimag;Caclcifor;Caclcifor;Calcamyl-24;Calcibenzamin;Calcamyl-24;Calcibenzamin;Camilca;Camilca;Chibro;Coneolent;Chibro;Coneolent;Cutaden;Cutaden;Dissol;Ear-dry;Dissol;Ear-dry;Egosol-bs;Egosol-bs;Evercil;Fermakzem;Evercil;Fermakzem;Flex-care;Flex-care;Glaucadrine;Glucocalcium;Glaucadrine;Glucocalcium;Kalopsisi;Kerapos;Kalopsisi;Kerapos;Kodomo smarin;Kodomo smarin;Komex;Lindemil;Komex;Lindemil;Macaldex;Macaldex;Mentol sedans sulfamidad;Neo-smarin dia;Mentol sedans sulfamidad;Neo-smarin dia;Neo-vagipurin;Neo-vagipurin;Normol;O-biol;Normol;O-biol;Oestro-gynedron;Oestro-gynedron;Ophtalmin;Otocaina;Ophtalmin;Otocaina;Pedoz;Pedoz;Phoscanol;Phoscanol;Poly-gynedron;Preferal;Poly-gynedron;Preferal;Proculin;Proculin;Rhinophenazol;Saddle mate;Rhinophenazol;Saddle mate;Swim-ear;Swim-ear;Swim-eye;Swim-eye;Timazincum;Timazincum;Tipolin;Tricho-gynedron;Tipolin;Tricho-gynedron;Unisol;Unisol;Vetacalin-m;Alpagelle;Vetacalin-m.

World Health Organization (WHO)

Boric acid and some borates were formerly extensively used as disinfectants and antiinflammatory agents. By the late 1960s an association between the death of many infants and application of high concentrations of boric acid contained in topical preparations used in the treatment of napkin rash had been established. This led to the restriction of the use of boric acid in pharmaceutical preparations by many regulatory authorities. In some countries it is now permitted only as an ingredient in ophthalmological preparations.

Hazard

Toxic via ingestion. Use only weak solu- tions. Irritant to skin in dry form.

Pharmaceutical Applications

Boric acid is used as an antimicrobial preservative in eye drops, cosmetic products, ointments, and topical creams. It is also used as an antimicrobial preservative in foods.
Boric acid and borate have good buffering capacity and are used to control pH; they have been used for this purpose in external preparations such as eye drops.
Boric acid has also been used therapeutically in the form of suppositories to treat yeast infections. In dilute concentrations it is used as a mild antiseptic, with weak bacteriostatic and fungistatic properties, although it has generally been superseded by more effective and less toxic disinfectants.

Safety

Boric acid is a weak bacteriostatic and antimicrobial agent, and has been used in topical preparations such as eye lotions, mouthwashes and gargles. It has also been used in US- and Japanese-approved intravenous products. Solutions of boric acid were formerly used to wash out body cavities, and as applications to wounds and ulcers, although the use of boric acid for these purposes is now regarded as inadvisable owing to the possibility of absorption. Boric acid is not used internally owing to its toxicity. It is poisonous by ingestion and moderately toxic by skin contact. Experimentally it has proved to be toxic by inhalation and subcutaneous routes, and moderately toxic by intraperitoneal and intravenous routes.
Boric acid is absorbed from the gastrointestinal tract and from damaged skin, wounds, and mucous membranes, although it does not readily permeate intact skin. The main symptoms of boric acid poisoning are abdominal pain, diarrhea, erythematous rash involving both skin and mucous membrane, and vomiting. These symptoms may be followed by desquamation, and stimulation or depression of the central nervous system. Convulsions, hyperpyrexia, and renal tubular damage have been known to occur.
Death has occurred from ingestion of less than 5 g in young children, and of 5–20 g in adults. Fatalities have occurred most frequently in young children after the accidental ingestion of solutions of boric acid, or after the application of boric acid powder to abraded skin.
The permissible exposure limit (PEL) of boric acid is 15 mg/m3 total dust, and 5 mg/m3 respirable fraction for nuisance dusts.
LdLo (man, oral): 429 mg/kg
LdLo (woman, oral): 200 mg/kg
LdLo (infant, oral): 934 mg/kg
LdLo (man, skin): 2.43 g/kg
LdLo (infant, skin): 1.20 g/kg
LD50 (mouse, oral): 3.45 g/kg
LD50 (mouse, IV): 1.24 g/kg
LD50 (mouse, SC): 1.74 g/kg
LD50 (rat, oral): 2.660 g/kg
LD50 (rat, IV): 1.33 g/kg
LD50 (rat, SC): 1.4 g/kg

Potential Exposure

Boric acid is a fireproofing agent for wood; a preservative, and an antiseptic. It is used in the manufacture of glass, pottery, enamels, glazes, cosmetics, cements, porcelain, borates, leather, carpets, hats, soaps; artificial gems; in tanning leather; printing, dyeing, painting, and photography.

storage

Boric acid is hygroscopic and should therefore be stored in an airtight, sealed container. The container must be labeled ‘Not for Internal Use’.

Shipping

UN 3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9—Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise the acid three times from H2O (3mL/g) between 100o and 0o, after filtering through sintered glass.Dry it to constant weight over metaboric acid in a desiccator. It is steam volatile. After two recrystallisations of ACS grade. it had Ag at 0.2 ppm. Its solubility (%) in H2O is 2.66 at 0o, 4.0 at 12o and 24 at 80o. At 100o it loses H2O to form metaboric acid (HBO2). When it is heated to redness or slowly to 200o, or over P2O5 in vacuo, it dehydrates to boric anhydride (B2O3) [1303-82-6] to give a white hard glass or crystals with m ~294o.The glass softens on heating and liquefies at red heat. It is an astringent, a fungicide and an antibacterial. [McCulloch J Am Chem Soc 59 2650 1937, Kelly J Am Chem Soc 63 1137 1941, Taylor & Cole J Chem Soc 70 1926, Conti J Soc Chem Ind 44 343T 1925.]

Incompatibilities

Boric acid decomposes in heat above 100 C, forming boric anhydride and water. Boric acid is hygroscopic; it will absorb moisture from the air. Boric acid aqueous solution is a weak acid; incompatible with strong reducing agents including alkali metals and metal hydrides (may generate explosive hydrogen gas); acetic anhydride, alkali carbonates, and hydroxides. Violent reaction with powdered potassium metal, especially if impacted. Attacks iron in the presence of moisture.

Incompatibilities

Boric acid is incompatible with water, strong bases and alkali metals. It reacts violently with potassium and acid anhydrides. It also forms a complex with glycerin, which is a stronger acid than boric acid.

Waste Disposal

Boric acids may be recovered from organic process wastes as an alternative to disposal.

Regulatory Status

Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (IV injections; ophthalmic preparations; (auricular) otic solutions; topical preparations). Reported in the EPA TSCA Inventory. In the UK, the use of boric acid in cosmetics and toiletries is restricted. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Orthoboric acid Preparation Products And Raw materials

Raw materials

Preparation Products


Orthoboric acid Suppliers

Global( 379)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hebei Lvyang Biotechnology Co.,Ltd
15030198922 +86 15030198922
0311-68052281 manager@ly-biotech.com CHINA 79 58
HuBei Bass Electronic Material Co.,Ltd
18971568347
bellarongl@basschemical.com CHINA 75 58
Hebei Chisure Biotechnology Co.LTD
13292891350 +86 13292890173
luna@speedgainpharma.com CHINA 1010 58
Wuhan Bosman Medicine Tech Co.,LTD
15377535057 027-88991195
sales@whbosman.com CHINA 986 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 19938 60
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8868 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2813 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29992 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 whatapp+8619930503282
86-0311-66562153 sales3@crovellbio.com CHINA 2692 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58

Related articles


View Lastest Price from Orthoboric acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-03-18 Orthoboric acid flake
10043-35-3
US $10.00 / KG 25Kg/Drum 99.99% 20 tons/month Wuhan Monad Medicine Tech Co.,LTD
2021-04-01 Orthoboric acid
10043-35-3
US $0.00 / Kg/Drum 1KG 99.9% 100000kg per month Wuhan Mulei New Material Technology Co. Ltd
2021-03-26 boric acid flakes
10043-35-3
US $100.00 / KG 1KG 99.9% 10tons Hebei Lvyang Biotechnology Co.,Ltd

Orthoboric acid Spectrum


10043-35-3(Orthoboric acid )Related Search:


Copyright 2017 © ChemicalBook. All rights reserved