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Pantoprazole structure
Chemical Name:
BY-1023;SKF-96022;Patoprazole;PANTOPRAZOLE;Pantoprozole;Pantoprazole&Int.;Pantoprazole Acid;Pantoprazole USP/EP/BP;Pantoprazole (Protonix);PANTOPRAZOLE SODIUM 98-102%
Molecular Formula:
Formula Weight:
MOL File:

Pantoprazole Properties

Melting point:
139-140° (dec)
Boiling point:
586.9±60.0 °C(Predicted)
1.51±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pKa1 3.92; pKa2 8.19(at 25℃)
CAS DataBase Reference
102625-70-7(CAS DataBase Reference)
ATC code
  • Risk and Safety Statements
Hazard Codes  Xn
Risk Statements  20/21/22-37/38-41-48
Safety Statements  22-26-36/37/39-45

Pantoprazole price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21345 Pantoprazole ≥98% 102625-70-7 250mg $25 2021-03-22 Buy
Cayman Chemical 21345 Pantoprazole ≥98% 102625-70-7 500mg $38 2021-03-22 Buy
Cayman Chemical 21345 Pantoprazole ≥98% 102625-70-7 1g $55 2021-03-22 Buy
Cayman Chemical 21345 Pantoprazole ≥98% 102625-70-7 5g $195 2021-03-22 Buy

Pantoprazole Chemical Properties,Uses,Production


Pantoprazole, an irreversible proton pump inhibitor, reached its first market worldwide in Germany for acute treatment of gastric and duodenal ulcers and gastroesophageal reflux disease. Proton pump inhibitors are more effective than other strategies in inhibiting acid secretion since they function at the final step of acid production, therefore, provide superior symptom relief and healing in all acid related diseases. As the third substituted benzimidazole proton pump inhibitor marketed, pantoprazole not only has superior ulcer-preventing effect but also is more potent than omeprazole in healing acetic acid-induced gastric and duodenal ulcers with extremely low acute toxicity. The mechanism of action for this class of compounds has been suggested to be mediated via the protonated form of the molecule which selectively reacts with cysteines present on the extracytoplasmic face of the enzyme to form covalent disulfide bonds.


Byk Gulden (Germany)


proton pump inhibitor, gastric acid release inhibitor, antiulcer


ChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.

Manufacturing Process

2-Chloromethyl-4,5-dimethoxy-3-methylpyridinium chloride (about 1.5 g) are added to a solution of 5-difluoromethoxy-1H-benzimidazole-2-thiol in 10 ml of ethanol and 10 ml of 1 N sodium hydroxide solution. The yellow reaction mixture is stirred at 20°C for 1 hour, a further 10 ml of water are added, whereupon a colorless solid precipitates out, the mixture is stirred for a further 5 hours and filtered and the residue is rinsed with 1 N sodium hydroxide solution and water and dried to constant weight. The 5difluoromethoxy-2-[(4,5-dimethoxy-2-pyridyl)methylthio]-1H-benzimidazole is obtained as an oil.
5-Difluoromethoxy-2-[(4,5-dimethoxy-2-pyridyl)methylthio]-1H-benzimidazole (about 1 g) are dissolved in 10 ml of dioxane and 2 ml of 1 N sodium hydroxide solution. An equimolar amount of a titrated aqueous sodium hypochlorite solution, to which 1 mole per liter of sodium hydroxide solution has been added, is first added dropwise, while cooling with ice. After one hour a further equivalent and after 3 hours half the equimolar amount of sodium hypochlorite are added, to achieve complete reaction. After a reaction time of 4 hours, 5 ml of 5% strength sodium thiosulfate solution and another 25 ml of dioxane are added and the upper dioxane phase is separated off, washed once with 5 ml of sodium thiosulfate solution and concentrated on a rotary evaporator. The oily residue is dissolved in 20 ml of water and 10 ml of ethyl acetate and the solution is brought to pH 7 with about 100 ml of a buffer solution of pH 6.8. The solid which has precipitated out is filtered off with suction over a suction filter, washed with water, extracted by stirring at 0C with acetone and dried. 5-Difluoromethoxy-2-[(4,5-dimethoxy-2pyridyl)methanesulfinyl]-1H-benzimidazole is prepared; yield about 85%.

brand name

Pantozol; Rifun

Therapeutic Function


Veterinary Drugs and Treatments

Pantoprazole may be useful in treating or preventing gastric acidrelated pathologies in dogs, cats, foals and camelids, particularly when the intravenous route is preferred. Pantoprazole is available in both intravenous and oral tablet (delayed-release) formulations. One study (Bersenas, Mathews et al. 2005) performed in dogs, comparing the gastric pH effects of intravenous pantoprazole with oral omeprazole, intravenous ranitidine, and intravenous famotidine, found at the dosages used, that pantoprazole was more effective than ranitidine, but similar to famotidine, and that oral omeprazole was more effective in maintaining intragastric pH >3 for a longer period than pantoprazole.
Pantoprazole has been shown to directly reduce in vitro counts of H. pylori and is used in some H. pylori treatment protocols for humans.

Pantoprazole Preparation Products And Raw materials

Raw materials

Preparation Products

Pantoprazole Suppliers

Global( 180)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 CHINA 3013 60
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
BOC Sciences
1-631-614-7828 United States 19752 58
0371-55170695 CHINA 26742 58
86-18523575427 CHINA 47498 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 CHINA 29864 58
Shaanxi Dideu Medichem Co. Ltd
029-88380327 CHINA 3993 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu CHINA 13187 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418697 CHINA 37441 58
Wuhan Monad Medicine Tech Co.,LTD
18771942761 02768782018 CHINA 1000 58

View Lastest Price from Pantoprazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-08 Pantoprazole
US $1.00 / g 1KG 99% 30 Tons Wuhan wingroup Pharmaceutical Co., Ltd
2021-11-02 Pantoprazole
US $444.00 / Kg/Bag 1Kg/Bag 99% 20T Baoji Guokang Healthchem co.,ltd
2021-08-31 pantoprazole
US $50.00 / KG 1Kg/Bag 99.99% 20 tons/month Wuhan Monad Medicine Tech Co.,LTD

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