ChemicalBook
Chinese english Germany Korea

オレイン酸

オレイン酸 化学構造式
112-80-1
CAS番号.
112-80-1
化学名:
オレイン酸
别名:
オレイン酸;オレイン酸(8℃)蒸留品;CIS-9-オクタデセン酸;オイレン酸;(Z)-オクタデカ-9-エン酸;オレイン酸標準品;(Z)-9-オクタデセン酸;オレイン酸, 植物由来;オレイン酸, 99+%;(9Z)-オクタデセン酸
英語化学名:
Oleic acid
英語别名:
k52;G18;D100;K 52;SOCS;NAA35;(cis);groco2;groco4;groco6
CBNumber:
CB7228241
化学式:
C18H34O2
分子量:
282.46
MOL File:
112-80-1.mol

オレイン酸 物理性質

融点 :
13-14 °C(lit.)
沸点 :
360 °C
比重(密度) :
0.89 g/mL at 25 °C(lit.)
蒸気密度:
1.03 (vs air)
蒸気圧:
52 mm Hg ( 37 °C)
屈折率 :
n20/D 1.377
FEMA :
2815 | OLEIC ACID
闪点 :
133 °F
貯蔵温度 :
-20°C
溶解性:
Miscible with ethanol, ether, acetone, chloroform, dimethyl formamide and dimethyl sulfoxide.
外見 :
Liquid
酸解離定数(Pka):
pKa 5.35(H2O,t =25) (Uncertain)
比重:
0.892 (20/4℃)
色:
Colorless to pale yellow
臭い (Odor):
Peculiar Lard-Like
水溶解度 :
negligible
Sensitive :
Air Sensitive
Merck :
14,6828
JECFA Number:
333
BRN :
1726542
親水性親油性バランス(HLB値):
1
安定性::
Stable. Combustible. Incompatible with strong oxidizing agents, aluminium.
InChIKey:
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
CAS データベース:
112-80-1(CAS DataBase Reference)
NISTの化学物質情報:
9-Octadecenoic acid (Z)-(112-80-1)
EPAの化学物質情報:
Oleic acid (112-80-1)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  T,Xi
Rフレーズ  23/24/25-34-40-43-36/37/38-38
Sフレーズ  36/37-37/39-26-36-36/37/39
RIDADR  UN 1198 3/PG 3
WGK Germany  2
RTECS 番号 LP8925000
10
自然発火温度 363°C
TSCA  Yes
HSコード  29161500
有毒物質データの 112-80-1(Hazardous Substances Data)
毒性 LD50 i.v. in mice: 230±18 mg/kg (Or, Wretlind)
消防法 危険物第4類第三石油類(非水溶性)
化審法 (2)-609, (2)-975 届出不要化学物質
絵表示(GHS)
注意喚起語 Warning
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 P264, P280, P302+P352, P321,P332+P313, P362
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 P264, P280, P305+P351+P338,P337+P313P
H320 眼刺激 眼に対する重篤な損傷性/眼刺激 性 2B 警告 P264, P305+P351+P338,P337+P313
注意書き
P264 取扱い後は皮膚をよく洗うこと。
P264 取扱い後は手や顔をよく洗うこと。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P321 特別な処置が必要である(このラベルの... を見よ)。
P332+P313 皮膚刺激が生じた場合:医師の診断/手当てを受けるこ と。
P337+P313 眼の刺激が続く場合:医師の診断/手当てを受けること。

オレイン酸 価格 もっと(80)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01W0115-0340 オレイン酸 99.0+%(cGC)
Oleic Acid 99.0+%(cGC)
112-80-1 1g ¥3100 2021-03-23 購入
富士フイルム和光純薬株式会社(wako) W01W0115-0340 オレイン酸 99.0+%(cGC)
Oleic Acid 99.0+%(cGC)
112-80-1 10g ¥7000 2021-03-23 購入
東京化成工業 O0011 オレイン酸 >85.0%(GC)
Oleic Acid >85.0%(GC)
112-80-1 25mL ¥1900 2021-03-23 購入
東京化成工業 O0011 オレイン酸 >85.0%(GC)
Oleic Acid >85.0%(GC)
112-80-1 500mL ¥4600 2021-03-23 購入
関東化学株式会社(KANTO) 31028-01 オレイン酸
Oleic acid
112-80-1 500mL ¥1900 2021-03-23 購入

オレイン酸 MSDS


cis-9-Octadecenoic acid

オレイン酸 化学特性,用途語,生産方法

外観

無色~黄色, 澄明の液体

定義

本品は、次の化学式で表される不飽和脂肪酸である。

溶解性

エタノールに極めて溶けやすく、水にほとんど溶けない。

用途

界面活性剤

化粧品の成分用途

洗浄剤、香料

効能

乳化剤

使用上の注意

不活性ガス封入 空気中での酸化又は光によって次第に褐色となる。

説明

Oleic acid has a faint fatty odor.

化学的特性

Oleic acid has a faint, fatty odor. This acid darkens on oxidation with a lard-like odor and taste.

化学的特性

Ayellowish to pale brown, oily liquid with a characteristic lard-like odor and taste.
Oleic acid consists chiefly of (Ζ)-9-octadecenoic acid together with varying amounts of saturated and other unsaturated acids. It may contain a suitable antioxidant.

化学的特性

Oleic acid, C17H33COOH, also known as red oil, elaine oil, and octadecenoic acid, is a yellowish unsaturated fatty acid with an aroma similar to lard. It is insoluble in water, but soluble in most organic solvents. Oleic acid is the main component in cooking and olive oils.It is used for making aluminum oleate, which thickens lubricating oil, and in the preparation of soaps and cosmetics.

天然物の起源

Reported found in apple, banana, cranberry, guava, grapes, melon, papaya, ginger, hop oil, ginger, beef fat, beer, rum, whiskies, cider, sherry, tea, goat milk, butterfat, celery, cheese, blue cheese, munster cheese, other cheeses, cognac, country cured ham, pork fat, potato, raspberry oil, tomato, peanut oil, coconut meat, avocado, mushroom, fenugreek, tamarind, kelp, cardamom, rice, dill seed, sake, buckwheat, malt, wort, roasted chicory root and cape gooseberry.

使用

Oleic Acid is an unsaturated fatty acid that functions as a lubricant, binder, and defoamer.

使用

Oleic acid is a monounsaturated omega-9 fatty acid. Oleic Acid is obtained by the hydrolysis of various animal and vegetable fats and oils. Oleic Acid is used as an emulsifying or solubilizing agent i n aerosol products.

使用

oleic acid is also known as omega-9. oleic acid can improve the skinpenetration abilities of a preparation’s other components. An essential fatty acid, it is obtained from various animal and vegetable fats and oils, and may be mildly irritating to the skin.

定義

ChEBI: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.

調製方法

Oleic acid is obtained by the hydrolysis of various animal and vegetable fats or oils, such as olive oil, followed by separation of the liquid acids. It consists chiefly of (Ζ)-9-octadecenoic acid. Oleic acid that is to be used systemically should be prepared from edible sources.

定義

cis-9-octadecenoic acid (or oleic acid) is a naturally occurring carboxylic acid present (as glycerides) in fats and oils:
CH3(CH2)7CH:CH(CH2)7COOH.

定義

octadecenoic acid: A straightchainunsaturated fatty acid with theformula C17H33COOH. Cis-octadec-9-enoic acid has the formulaCH3(CH2)7CH:CH(CH2)7COOH.The glycerides of this acid are foundin many natural fats and oils.

定義

oleic acid: An unsaturated fattyacid with one double bond,CH3(CH2)7CH:CH(CH2)7COOH; r.d. 0.9;m.p. 13°C. Oleic acid is one of themost abundant constituent fattyacids of animal and plant fats, occurringin butterfat, lard, tallow,groundnut oil, soya-bean oil, etc.Its systematic chemical name is cisoctadec-9-enoic acid.

製造方法

Obtained from fats.

一般的な説明

Colorless to pale yellow liquid with a mild odor. Floats on water.

空気と水の反応

Keep cis-9-Octadecenoic acid well closed; protect cis-9-Octadecenoic acid from air and light. . May form peroxides upon exposure to air. This is taken to account for an explosion that occurred, by the mixing of the acid with aluminum, [J. Chem. Educ., 1956, 36, 308]. Water Insoluble.

反応プロフィール

cis-9-Octadecenoic acid is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in cis-9-Octadecenoic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.

健康ハザード

Industrial use of compound involves no known hazards. Ingestion causes mild irritation of mouth and stomach. Contact with eyes or skin causes mild irritation.

火災危険

cis-9-Octadecenoic acid is combustible.

応用例(製薬)

Oleic acid is used as an emulsifying agent in foods and topical pharmaceutical formulations. It has also been used as a penetration enhancer in transdermal formulations,to improve the bioavailability of poorly water-soluble drugs in tablet formulations, and as part of a vehicle in soft gelatin capsules, in topical microemulsion formulations,in oral self-emulsifying drug delivery systems,in oral mucoadhesive patches,and in a metered dose inhaler.Oleic acid was shown to be an important factor in the hypoglycemic effect produced by multiple emulsions containing insulin intended for intestinal delivery of insulin.
The phase behavior of sonicated dispersions of oleic acid has been described,and mechanisms for the topical penetrationenhancing actions of oleic acid have been presented.
Oleic acid has been reported to act as an ileal ‘brake’ that slows down the transit of luminal contents through the distal portion of the small bowel.
Oleic acid labeled with 131I and 3H is used in medical imaging.

安全性プロファイル

Poison by intravenous route. Mildly toxic by ingestion. Mutation data reported. A human skin and eye irritant. Questionable carcinogen with experimental tumorigenic data. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical. The peroxidzed acid explodes on contact with aluminum. Potentially dangerous reaction with perchloric acid + heat. When heated to decomposition it emits acrid smoke and irritating fumes.

安全性

Oleic acid is used in oral and topical pharmaceutical formulations.
In vitro tests have shown that oleic acid causes rupture of red blood cells (hemolysis), and intravenous injection or ingestion of a large quantity of oleic acid can therefore be harmful. The effects of oleic acid on alveolar and buccal epithelial cells in vitro have also been studied; the in vitro and in vivo effects of oleic acid on rat skin have been reported. Oleic acid is a moderate skin irritant; it should not be used in eye preparations.
An acceptable daily intake for the calcium, sodium, and potassium salts of oleic acid was not specified by the WHO since the total daily intake of these materials in foods was such that they did not pose a hazard to health.
LD50 (mouse, IV): 0.23 g/kg
LD50 (rat, IV): 2.4 mg/kg
LD50 (rat, oral): 74 g/kg

Carcinogenicity

Some recent studies suggested that oleic acid may decrease the incidence of mammary gland tumors of some rodent species. In a reviewof several fatty acids, Ip concludes that there is little evidence for the protective effect of oleic acid on the development of cancer.

貯蔵

On exposure to air, oleic acid gradually absorbs oxygen, darkens in color, and develops a more pronounced odor. At atmospheric pressure, it decomposes when heated at 80–100°C.
Oleic acid should be stored in a well-filled, well-closed container, protected from light, in a cool, dry place.

純化方法

Purify the acid by fractional crystallisation from its melt, followed by molecular distillation at 10 -3mm, or by conversion to its methyl ester, the free acid can be crystallised from acetone at -40o to -45o (12mL/g). For purification by the use of lead and lithium salts, see Keffler and McLean [J Soc Chem Ind (London) 54 176T 1935]. Purification based on direct crystallisation from acetone is described by Brown and Shinowara [J Am Chem Soc 59 6 1937, pK White J Am Chem Soc 72 1857 1950]. [Beilstein 2 H 463, 2 I 198, 2 II 429, 2 III 1387, 2 IV 1641.]

不和合性

Incompatible with aluminum, calcium, heavy metals, iodine solutions, perchloric acid, and oxidizing agents. Oleic acid reacts with alkalis to form soaps.

規制状況(Regulatory Status)

GRAS listed. Included in the FDA Inactive Ingredients Database (inhalation and nasal aerosols, tablets, topical and transdermal preparations). Included in nonparenteral medicines (metered dose inhalers; oral capsules; oral prolonged release granules; topical creams and gels) licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

オレイン酸 上流と下流の製品情報

原材料

準備製品


オレイン酸 生産企業

Global( 527)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Masteam Bio-tech Co., Ltd.
86-15897918789 86-15200345168
bruce.lei@masteam.com CHINA 153 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20010 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 3001 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58

112-80-1(オレイン酸)キーワード:


  • 112-80-1
  • 9-cis-Octadecenoicacid
  • 9-Octadecenoic acid, cis-
  • 9Octadecenoicacid(9Z)
  • Oleic acid, AR
  • OLEIC ACID, 90%, TECHNICALOLEIC ACID, 90%, TECHNICALOLEIC ACID, 90%, TECHNICALOLEIC ACID, 90%, TECHNICAL
  • Oleic acid CETEARYL ALCOHOL Manufacturer
  • Oleic Acid - CAS 112-80-1 - Calbiochem
  • OmniPur Oleic Acid
  • 9-Octadecenoicacid(9Z)-
  • 9-Octadecenoicacid(Z)
  • 9-Octadecenoicacid(Z)-
  • 9-Octadecenoicacid,(Z)-
  • 9-Octadecensαure,(Z)-
  • acideoleique
  • Century cd fatty acid
  • centurycdfattyacid
  • cis-9-octadecenoicaci
  • cis-D9-octadecenoicacid
  • cis-delta(9)-octadecenoicacid
  • cis-delta(Sup9)-Octadecenoic acid
  • cis-delta(sup9)-octadecenoicacid
  • cis-delta9-octadecenoic acid
  • cis-delta9-Octadecenoate
  • cis-Oleic Acid
  • cis-oleicacid
  • D100
  • D9-cis-octadecenoicacid
  • delta(9)-cis-oleicacid
  • delta(Sup9)-cis-Oleic acid
  • delta9-cis-Oleic acid
  • オレイン酸
  • オレイン酸(8℃)蒸留品
  • CIS-9-オクタデセン酸
  • オイレン酸
  • (Z)-オクタデカ-9-エン酸
  • オレイン酸標準品
  • (Z)-9-オクタデセン酸
  • オレイン酸, 植物由来
  • オレイン酸, 99+%
  • (9Z)-オクタデセン酸
  • 不飽和高級脂肪酸
  • 高級脂肪酸 & 高級アルコール
  • 抗酸化剤
  • 生化学
Copyright 2017 © ChemicalBook. All rights reserved