ChemicalBook
Chinese english Germany Korea

ビタミンA

ビタミンA 化学構造式
68-26-8
CAS番号.
68-26-8
化学名:
ビタミンA
别名:
ビタミンA1;(2E,4E,6E,8E)-3,7-ジメチル-9-(2,6,6-トリメチル-1-シクロヘキセン-1-イル)-2,4,6,8-ノナテトラエン-1-オール;ニオ-A-レット;ボガン;全trans-レチノール;アクセロフトール;プレパリン;ビデオステロール;アビトール;ビー-アルファ;アビボン;アクセロール;all-trans-レチノール;アオラル;アタフ;アポスタビット;ビタミンA1アルコール;ビタミンAアルコール;アファキシン;テスタボール
英語化学名:
all-trans-Retinol
英語别名:
Acon;Atav;-1-ol;Aoral;A-Sol;Atars;Avita;Vogan;Vafol;Vio-A
CBNumber:
CB8194893
化学式:
C20H30O
分子量:
286.45
MOL File:
68-26-8.mol

ビタミンA 物理性質

融点 :
61-63 °C(lit.)
沸点 :
368.81°C (rough estimate)
比重(密度) :
0.9933 (rough estimate)
屈折率 :
1.641
闪点 :
-26 °C
貯蔵温度 :
-20°C
酸解離定数(Pka):
14.09±0.10(Predicted)
外見 :
crystalline
色:
yellow to orange
水溶解度 :
Practically insoluble inwaterorglycerol; soluble in absolute alcohol,methanol,℃hloroform, ether, fats and oils.
Sensitive :
Moisture & Light Sensitive
Merck :
13,10073
BRN :
403040
安定性::
Stable, but light and air sensitive. Incompatible with strong acids, strong oxidizing agents.
CAS データベース:
68-26-8(CAS DataBase Reference)
EPAの化学物質情報:
Retinol (68-26-8)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  Xn,N,F,T
Rフレーズ  22-38-67-65-62-51/53-48/20-11-43-61-63-36/38
Sフレーズ  36/37-61-62-45-53-16-33-29-9-36/37/39-26
RIDADR  UN 1208 3/PG 2
WGK Germany  3
RTECS 番号 VH6750000
8-10-16-23
TSCA  Yes
HSコード  29362100
有毒物質データの 68-26-8(Hazardous Substances Data)
毒性 LD50 (10 day) in mice (mg/kg): 1510 i.p.; 2570 orally (Kamm)
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H225 引火性の高い液体および蒸気 引火性液体 2 危険 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 飲み込むと有害 急性毒性、経口 4 警告 P264, P270, P301+P312, P330, P501
H317 アレルギー性皮膚反応を起こすおそれ 感作性、皮膚 1 警告 P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 P264, P280, P305+P351+P338,P337+P313P
H360 生殖能または胎児への悪影響のおそれ 生殖毒性 1A, 1B 危険
H413 長期的影響により水生生物に有害のおそれ 水生環境有害性、慢性毒性 4
注意書き
P201 使用前に取扱説明書を入手すること。
P210 熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P308+P313 暴露または暴露の懸念がある場合:医師の診断/手当てを 受けること。
P337+P313 眼の刺激が続く場合:医師の診断/手当てを受けること。
P403+P235 換気の良い場所で保管すること。涼しいところに 置くこと。
P405 施錠して保管すること。

ビタミンA 価格 もっと(26)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTR1876 all-trans-レチノール
all-trans-Retinol
68-26-8 25mg ¥8800 2021-03-23 購入
富士フイルム和光純薬株式会社(wako) W01LKTR1876 all-trans-レチノール
all-trans-Retinol
68-26-8 100mg ¥12400 2021-03-23 購入
関東化学株式会社(KANTO) 34707-1A all‐trans‐レチノール 95%
all‐trans‐Retinol 95%
68-26-8 100mg ¥10100 2021-03-23 購入
Sigma-Aldrich Japan 17772 レチノール ≥95.0% (HPLC), ~2700?U/mg
Retinol ≥95.0% (HPLC), ~2700?U/mg
68-26-8 250mg ¥17600 2021-03-23 購入
Sigma-Aldrich Japan 17772 レチノール ≥95.0% (HPLC), ~2700?U/mg
Retinol ≥95.0% (HPLC), ~2700?U/mg
68-26-8 1g ¥46480 2021-03-23 購入

ビタミンA 化学特性,用途語,生産方法

定義

本品は、共役不飽和脂環式アルコールである。

解説

C20H30O(286.45).アクセロフトール(axerophthol),ビタミン A1,レチノール,A1 アルコールともいう.ビタミンAはretinolを意味し,ビタミン A2 発見以来,区別するためビタミン A1 とよぶ.次のようにオールトランス形の化学構造をもつ.""淡黄色の柱状結晶.融点62~64 ℃.λmax 325 nm(2-プロパノール)で吸光係数E1cm1%1830.多くの有機溶媒,油脂に可溶,水に不溶.ビタミンAのクロロホルム溶液はSbCl3によって深青色を呈し,その吸収極大は620 nm にあり,E1cm1%5070である.そのほかの呈色試薬としては2,3-ジクロロ-1-プロパノール(GDH)がある.空気酸化を受けやすく,熱や紫外線に対しても不安定である.魚肝油,ミルク,バター,卵黄,胚芽に存在し,肝油類の不けん化部分から得るか,または合成する.生体内では遊離アルコール型のほか,パルミチン酸,ステアリン酸,オレイン酸などのエステルとして存在することが認められている.ビタミンAの欠乏は夜盲症,皮膚の異常乾燥症,および角化亢進,骨変化,神経変性および成長発育の停止の病因となる.A1 アルデヒドは網膜桿(かん)状体の感光色素タンパク質であるロドプシンの構成成分である.橙黄色の結晶.融点61~62 ℃.SbCl3呈色の吸収極大は664 nm にある.ロドプシン中の A1 アルデヒドは Δ11-シス形であるが,光の刺激を受けるとオールトランス形に異性化され,同時にタンパク部分から解離する.A1 酸は視覚に対しては効果はないが,正常な発育と正常な皮膚を保つためには A1 アルコールと同様の効果を示す.淡黄色の針状結晶.融点180 ℃.SbCl3で赤紫色を呈し,吸収極大は573 nm にある.ビタミン A2 は淡水魚の肝油から発見され,次のような構造式をもつ."ビタミン A1 と吸収スペクトルは若干異なり(λmax 351 nm),生理活性はビタミン A1 の約40% である.ビタミン A1 と同様,それに対応するアルデヒド,酸,エステルなどがある.高等植物や原生生物などに広く存在する.カロテノイド(たとえば,β-カロテン)は,動物体内に摂取され小腸壁でビタミンA作用物質(A1,A2)に転換されるビタミンの前駆物質で,プロビタミンA(provitamin A)とよばれる.[CAS 68-26-8]
森北出版「化学辞典(第2版)

化粧品の成分用途

皮膚コンディショニング剤

効能

ビタミンA補充薬, レチノイン酸受容体(RAR)作動薬

商品名

チョコラ (サンノーバ)

説明

Human vitamin A is derived from the natural food. Natural vitamin A exists in dif ferent forms. In animal tissues, vitamin A is present in the form of retinoids. However, in plants, the form of vitamin A called carotenoids is contained in the green, orange, and yellow plant tissue. Vitamin A compounds such as retinol, reti nal, carotene, and so on from these foods can be converted to vitamin A in the human body. Therefore, food is the main source of vitamin A.
As early as 1000 years ago, the Qian Jin Yao Fang written by Sun Simiao in Tang Dynasty recorded that animal liver can cure night blindness. This is the early recognition in vitamin A supplementation. The traditional Chinese medicine books also recorded that nourishing the liver can improve eyesight. Researches on the therapy of vitamin A deficient-diseases are mainly related to nourishing the liver and kidney, supplementing essence and blood, and activating qi

化学的特性

Yellow-Orange Powder

物理的性質

Vitamin A1 (VA1), Molecular formula, C20H30O; MW, 286.45; CAS, 68-26-8. Melting point: 62–64 °C. Boiling point: 137–138 °C
VA2, Molecular formula, C20H28O; MW, 284.44; Melting point: 17–19 °C.

Originator

Acon ,Endo

来歴

The vitamin research is the great achievement in the development of life sciences, while human beings only took half a century to discover and understand vitamins. However, everything is still very difficult for scientists in the early stage of vitamin discovery. From 1913 to 1915, Elmer McCollum and Marguerite Davis indicated that the growth rate was maintained by at least two different kinds of growth factors: one can be separated from eggs or butter, and the other one which multiple neuritis of chicks and pigeons can be extracted by water; thus they were named fat-soluble vitamin A and water-soluble vitamin B.prevented
In 1919, the researchers demonstrated that fat-soluble vitamin A not only sup ported the rate of growth but also prevented eye dryness and night blindness in the process of property study. In 1920, Dr. J.C. Drummond named this active lipid as vitamin A. It exists in cod liver oil and prevents the occurrence of eye dryness and night blindness.

使用

Vitamin A1 (retinal) is produced from (3-carotene, which can be obtained by fermentation of corn, soybean meal, kerosene, thiamin, and oc-ionone. The dry-mass after fermentation contains 120 to 150 g product/kg.

使用

mucolytic

使用

vitamin A (Retinol) is the fat-soluble vitamin a which is required for new cell growth and prevention of night blindness. There is no appreciable loss by heating or freezing, and it is stable in the absence of air. Sources include liver, fortified margarine, egg, and milk. Vitamin A palmitate can be found in frozen egg substitute.

使用

Occurs preformed only in animals; metabolized from carotenoids, such β-carotene, in the intestinal mucosa. Dietary sources include liver, milk, butter, cheese, eggs and fish liver oils or as carotenoi s from fruits and vegetables. Stored primarily in the liver in esterified form; transported in the blood by retinol binding protein (RBP). Nutritional factor.

使用

Atracurium Besilate intermediate

使用

retinol is a retinoid considered to be a skin revitalizer. It is reported to enhance skin radiance and treat conditions associated with chronological aging, such as wrinkles and fine lines, as well as dermatological disorders, including acne, follicular and lesion papules, actinic keratosis, oily skin, and rosacea. According to clinical dermatologists, retinol is one of the few substances with a demonstrated ability to reduce and prevent fine lines and wrinkles. It is able to alter the behavior of aged cells so they act in a more youthful manner. It is considered necessary for normal epidermal cell growth and differentiation and stimulates the production of new blood vessels in the skin, improving skin tone. In addition, retinol has anti-oxidant capacities and protects dermal fibers by counteracting the increased activity of enzymes that degrade collagen and elastin when the skin is exposed to uV rays. Retinol can be drying to the skin when used for a prolonged period of time or in concentrations that are too high. A weaker retinoid than retinoic acid, retinol converts to retinoic acid once on the skin. When compared to retinoic acid, retinol has an increased penetration potential and is less irritating, making it an effective ingredient for anti-aging products. The anti-aging benefits of topically treating skin with retinol are based on its penetration ability, which allows it to reach the sites in the skin requiring treatment. When used on sensitive skin for a prolonged period of time or in concentrations that are too high, retinol can cause dermatitis.

適応症

Vitamin A, or retinol, is essential for the proper maintenance of the functional and structural integrity of epithelial cells, and it plays a major role in epithelial differentiation. Bone development and growth in children have also been linked to adequate vitamin A intake. Vitamin A, when reduced to the aldehyde 11-cis-retinal, combines with opsin to produce the visual pigment rhodopsin. This pigment is present in the rods of the retina and is partly responsible for the process of dark adaptation.

定義

ChEBI: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.

Manufacturing Process

Manufacturing process for Vitamin A includes these steps as follows: Step A: Synthesis of Preparation of ethyl ether of ethynyl-β-ionol;Step B: Coupling Reaction; Step C:Semi-Hydrogenation of Coupling Product;Step D:Hydrolysis of Semi-Hydrogenated Coupling Product. Separation of Vitamin A from the product obtained was achieved by acetylating the total reaction product using pyridine-acetic anhydride at room temperature and chromatographing on alumina neutralized with acetic acid. A fairly clean separation was achieved. The Vitamin A acetate fraction was sufficiently pure to become crystallized from pentane at -15°C when seeded with a pure Vitamin A acetate crystal.
When the Vitamin A acetate was converted to the alcohol form of Vitamin A, the final product showed the characteristic infrared and ultraviolet absorption curves for Vitamin A. Similar results were obtained using as co-solvents (with the liquid ammonia) ethylene diamine and ether; pentane; tetrahydrofuran; diethylamine and hexamethylphosphoramide.

brand name

Avibon.

Therapeutic Function

Vitamin

世界保健機関(WHO)

Vitamin A, a fat-soluble vitamin, is used in the treatment and prevention of vitamin A deficiency resulting from inadequate dietary intake. It has been demonstrated to be teratogenic at high doses (more than 25,000 IU per day). Daily dosages of less than 10000 IU seem to be free of this risk. Retinol (vitamin A) is listed in the WHO Model List of Essential Drugs.

Synthesis Reference(s)

Tetrahedron, 51, p. 2435, 1995 DOI: 10.1016/0040-4020(94)01108-C

薬理学

Intake of vitamin A precursors, such as carotenoids, retinyl esters, retinol, and reti nal, can maintain the epithelial cell differentiation, normal proliferation, and visual function. All of these substances can be metabolized into retinol, retinal, and reti noic acid. But unlike retinol and retinal, retinoic acid cannot be reduced to retinol and retinal. Intake of retinoic acid can only maintain the systemic function of vita min A.
Visual and vitamin A. 11-cis-retinal plays an important role as a photographic group of retinal cones and visual pigments in rod cells. 11-cis-retinal would be transformed into all-trans-retinal form under the light induction. The dissociation of all-trans retinal and opsin was coupled with the nerve stimulation of the brain’s visual center. By a series of biochemical processes, nerve impulses format in the rod cells at the end of synapse, and then the optic nerve conducts the nerve impulses along. The visual process is a component renewable cycle, and all-trans-retinal can be enzymatically modified to 11-cis form in dark conditions.
The systemic effects of vitamin A. Vitamin A not only significantly affects visual function but also has a greater physiological impact than visual function. Vitamin A deficiency destroys the visual cycle, leads to dark adaptation damage (night blind ness or nyctalopia), and destroys systemic function which is necessary to maintain life (e.g., corneal injury, infection, and hypoplasia). Vitamin A deficiency can lead to animal death.
Vitamin A functions in reproduction and embryonic development. Vitamin A plays an important role in the reproductive process of sperm production and ovula tion, but its biochemical basis is unclear. Vitamin A plays a key role in the develop ment of embryos and organism and maintenance of tissue function. The main organs affected by vitamin A deficiency are the heart, eye tissue, circulatory system, geni tourinary system, and respiratory system. Vitamin A is necessary for embryonic development.
Vitamin A functions on immune function. The lymphoid organs, cell distribu tion, histology, lymphocytes, and other characteristics will change when the ani mals lack vitamin A. Vitamin A deficiency can lead to immune function decrease, induce inflammation, and exacerbate inflammatory symptoms
Vitamin A functions in dermatology. Vitamin A plays an important role in main taining healthy skin. Vitamin A deficiency disrupts human keratin cell terminal dif ferentiation and makes the skin rough, dry, scaly, and clogged
It is reported that vitamin A can degrade malignant melanoma and T-cell lymphoma epidermal transfer, reduce the oil secretion of the common acne and the number of bacteria in the epidermis and capillaries, and inhibit immune response of monocytes and neutrophils.
Vitamin A plays an important role as an important function material in the body system, such as hematopoietic function, bone development, tumor prevention, and so on. Therefore, supplement of vitamin A is necessary for health requirements

臨床応用

Principal dietary sources of vitamin A are milk fat (cheese and butter) and eggs. Since it is stored in the liver, inclusion of liver in the diet also provides vitamin A. A plant pigment, carotene, is a precursor for vitamin A and is present in highly pigmented vegetables, such as carrots, rutabaga, and red cabbage.
An early sign of hypovitaminosis A is night blindness. This condition is related to the role of vitamin A as the prosthetic group of the visual pigment rhodopsin. The night blindness may progress to xerophthalmia (dryness and ulceration of the cornea) and blindness. Other symptoms of vitamin A deficiency include cessation of growth and skin changes due to hyperkeratosis.
Since vitamin A is a fat-soluble vitamin, any disease that results in fat malabsorption and impaired liver storage brings with it the risk of vitamin A deficiency; these conditions include biliary tract disease, pancreatic disease, sprue, and hepatic cirrhosis. One group at great risk are children from low-income families, who are likely to lack fresh vegetables (carotene) and dairy products (vitamin A) in the diet.

副作用

Acute hypervitaminosis A results in drowsiness, headache, vomiting, papilledema, and a bulging fontanel in infants. The symptoms of chronic toxicity include scaly skin, hair loss, brittle nails, and hepatosplenomegaly. Anorexia, irritability, and swelling of the bones have been seen in children. Retardation of growth also may occur. Liver toxicity has been associated with excessive vitamin A intake. Vitamin A is teratogenic in large amounts, and supplements should not be given during a normal pregnancy. The IOM has reported the UL of vitamin A to be 3,000 μg/day.

安全性プロファイル

Moderately toxic by ingestion. Human teratogenic effects by ingestion: developmental abnormalities of the craniofacial area and urogenital system. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

純化方法

Purify retinol by chromatography on columns of water-deactivated alumina and elute with 3-5% acetone in hexane. Separate the isomers by TLC plates on silica gel G, developed with pet ether (low boiling)/methyl heptanone (11:2). Store it in the dark, under N2, at 0o, or in Et2O, Me2CO or EtOAc. [See Gunghaly et al. Arch Biochem Biophys 38 75 1952, Beilstein 6 IV 4133.]

Toxicity evaluation

The exact mechanism leading to toxicity is not known. Both acute and chronic toxicity may occur.
Acute and Short-Term Toxicity (or Exposure)
Human
Acute toxicity is uncommon in adults. However, vitamin A ingestions of greater than 1 million IU in adults and greater than 300 000 IU in children have resulted in the development of increased intracranial pressure (symptoms described include headache, dizziness, vomiting, visual changes, and bulging fontanel in infants). Acute ingestions of greater than 12 000 IU per kilogram are also considered toxic.
Chronic Toxicity (or Exposure)
Human
Toxicity is more frequently seen with chronic ingestion of high doses of 30 000–50 000 IU per day. Vitamin A toxicity in children develops following chronic ingestion of 410 times the recommended daily allowance for weeks to months.
Malnutrition and individual tolerance may also be factors in predisposition to toxicity. Signs and symptoms of toxicity include vomiting, anorexia, agitation, fatigue, double vision, headache, bone pain, alopecia, skin lesions, increased intracranial pressure, and papilledema. Hepatic toxicity typically requires months or years of daily high doses of vitamin A. There are no known cases of vitamin A toxicity associated with beta-carotene ingestion.

ビタミンA 上流と下流の製品情報

原材料

準備製品


ビタミンA 生産企業

Global( 354)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 10003 58
Hebei Yime New Material Technology Co., Ltd.
+8617703311139
admin@china-yime.com China 273 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20012 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1009 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2941 58

68-26-8(ビタミンA)キーワード:


  • 68-26-8
  • Vitamin A1 alcohol
  • Vitamin A1 alcohol, all-trans-
  • Vitamin A1, all-trans-
  • vitamina1alcohol
  • vitamina1alcohol,alltrans
  • Vitavel A
  • Vitamin A (all-trans-Retinol)
  • VITAMIN-A-ALCOHOL SOLUTION, IN HEXANE (0 .25 MG/ML), 1X2 ML
  • VITAMIN A USP(CRM STANDARD)
  • VITAMIN A(RETINOL)(SECONDARY STANDARD)
  • VitaminAalkohol
  • Vitamin A Crystallization
  • ALL-TRANS-RETINOL (VITAMIN A ALCOHOL)
  • RETINOL (VITAMIN A)
  • ALL TRANS-RETINOL (VITAMIN A)
  • retinol solution
  • VITAMINA(FEED)
  • VITAMIN A(RETINOL)(SH)
  • Axerophthol, VitaminA alcohol, VitaminA, VitaminA1, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
  • all-trans-Retinol, Axerophthol, VitaminA alcohol solution, VitaminA1, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol
  • all-trans-Retinol,99+%
  • all-trans-Retinol,95%
  • RETINOL SYNTHETIC, >= 95% (HPLC), C&
  • RETINOL, BIOXTRA, >=97.5% (HPLC)&
  • (all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen
  • -1-ol
  • 2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
  • 21 CFR 182,5930
  • 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol
  • 6,8-nonatetraen-1-ol,3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-4
  • ビタミンA1
  • (2E,4E,6E,8E)-3,7-ジメチル-9-(2,6,6-トリメチル-1-シクロヘキセン-1-イル)-2,4,6,8-ノナテトラエン-1-オール
  • ニオ-A-レット
  • ボガン
  • 全trans-レチノール
  • アクセロフトール
  • プレパリン
  • ビデオステロール
  • アビトール
  • ビー-アルファ
  • アビボン
  • アクセロール
  • all-trans-レチノール
  • アオラル
  • アタフ
  • アポスタビット
  • ビタミンA1アルコール
  • ビタミンAアルコール
  • アファキシン
  • テスタボール
  • (2E,4E,6E,8E)-3,7-ジメチル-9-(2,6,6-トリメチル-1-シクロヘキセニル)-2,4,6,8-ノナテトラエン-1-オール
  • バフロール
  • アビタ
  • trans-レチノール
  • レチノール
  • all-trans-ビタミンA1
  • アルファリン
  • エピテリオール
  • アナトラA
  • アペクソール
  • アギオラン
  • オフタルミン
  • ビトペックス
  • ビタミン A
  • ALL‐TRANS‐レチノール
  • 代謝作用薬
Copyright 2017 © ChemicalBook. All rights reserved