벤조트리클로라이드 C화학적 특성, 용도, 생산
개요
Exhaustive chlorination of the side-chain of toluene leads to benzotrichloride (trichloromethyl
benzene, a,a,a-trichlorotoluene, phenyl chloroform) [98-07-7]. The compound was first synthesized in 1858 by L. SCHISCHKOFF and A. ROSING,
using the reaction of PCl5 with benzoyl chloride.
Benzotrichloride is now produced on a large
scale, since it serves as an important intermediate
in the preparation of acid chlorides (benzoyl
chloride), dyes, herbicides, pesticides, and other
products.
물리적 성질
Benzotrichloride is a colorless liquid with a
pungent odor and is irritating to the eyes and
mucous membranes. It fumes in moist air.Benzotrichloride is freely soluble in alcohol,
ether, and chloroform. It is only slightly soluble in
water (0.05 g/L at 5 ℃, 0.25 g/L at 39 ℃). The
solubility of chlorinein 100 g of benzotrichloride is 5.1 g at 30 ℃,
3.4 g at 50 ℃,
1.3 g at 100 ℃.
화학적 성질
Benzotrichloride is a combustible, colorless to
yellow-brown, oily liquid that fumes on contact with air. It
has a penetrating odor.
용도
α,α,α-Trichlorotoluene was used in determination of chlorinated toluenes in effluents of wastewater treatment plants and textile industries by closed loop stripping analysis.
용도
Benzotrichloride is used mainly to produce benzoyl chloride, for which purpose it is either
partially hydrolyzed with water or else reacted
with benzoic acid. It is also of some significance
in the production of pesticides (through transformation into benzotrifluoride), ultraviolet stabilizers, and dyes.
일반 설명
Benzotrichloride appears as a clear colorless to yellowish colored liquid with a penetrating odor. Denser than water and vapors are heavier than air. May be toxic by inhalation or ingestion. Burns skin, eyes, and mucous membranes. Insoluble in water. Used to make dyes and other chemicals.
공기와 물의 반응
Hydrolyzes in the presence of moisture. The reaction is rather slow due to low solubility in water.
반응 프로필
Benzotrichloride hydrolyzes in the presence of moisture. Benzotrichloride reacts with water, lime, ammonia, strong alkalis, organic amines, chlorates and acids.
위험도
Highly toxic by inhalation, fumes highly
irritant. Eye, skin, and upper respiratory tract irri-
tant. Probable carcinogen.
건강위험
Toxic by inhalation; fumes are highly irritating to skin and mucous membranes. May cause death or permanent injury after very short exposure to small quantities. A suspected carcinogen.
화재위험
Benzotrichloride may react violently with water. Fire may produce irritating or poisonous gases. Flammable/poisonous gases may accumulate in tanks and hopper cars. Materials may ignite combustibles (wood, paper, oil, etc.). Produces toxic and corrosive fumes when Benzotrichloride reacts with water or steam. Similar to hydrochloric acid; material will react with water or steam to produce toxic and corrosive fumes. Hydrolyzes in presence of water forming benzoic and hydrochloric acids.
Toxicology
The acute oral toxicity of benzotrichloride is
2180 mg/kg in male rats and 1590 mg/kg in
female rats. The inhalative LC50s are higher than
600 mg/m3 in male rats and about 500 mg/m3 in
female rats after a 4-h exposure. Benzotrichloride irritates the skin and eyes. The
compound proved to be mutagenic in bacterial test systems. Dermal application of benzotrichloride resulted in elevated tumor incidence
in mice.
잠재적 노출
Benzotrichloride is used as a chemical
and dye intermediate; extensively used in the dye industry
for the production of Malachite green, Rosamine,
Quinoline red, and Alizarin yellow A. It can also be used
to produce ethyl benzoate. Commercial grades may contain
hydrochloric acid, benzylidene chloride, or benzyl chloride.
Carcinogenicity
Benzotrichloride is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
운송 방법
UN2226 Benzotrichloride, Hazard class: 8;
Labels: 8—Corrosive material.
비 호환성
Benzotrichloride decomposes on heating,
on contact with acids and/or water, producing toxic and
corrosive hydrogen chloride and benzoic acid. Reacts violently
with strong oxidizers, iron and other metals, alkali
and earth alkali metals; bases and organic substances, and
may cause fire and explosions. On contact with air it emits
toxic and corrosive hydrogen chloride. Attacks many
metals in presence of water. Attacks many plastics.
폐기물 처리
Incineration with flammable
solvent added in incinerator with afterburner and alkaline
scrubber.
벤조트리클로라이드 준비 용품 및 원자재
원자재
준비 용품
