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Triclosan Suppliers list
Company Name: Zhonglan Industry Co., Ltd.
Tel: (86) 531-82956570
Products Intro: Product Name:TRICLOSAN
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Triclosan
Purity:99% Package:154/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Triclosan
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:3380-34-5
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Triclosan

Lastest Price from Triclosan manufacturers

  • Triclosan
  • US $2.00 / kg
  • 2018-12-24
  • CAS:3380-34-5
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: ask
Triclosan Basic information
Disinfectants Carcinogenicity Toothpaste Standard Chemical Properties Uses Production method
Product Name:Triclosan
Synonyms:2,4,4-trichloro-2-hydroxydiphenylether(irgasandp-300);2’-hydroxy-2,4,4’-trichloro-phenylethe;5-chloro-2-(2,4-dichlorophenoxy)-pheno;2,4,4'-TRICHLORO-2'-HYDROXYDIPHENYL ETHER;2,4,4-TRICHLORO-2-HYDROXYDIPHENYL ETHER;TRICLOSAN;trichloro-2'-hydroxydiphenylether;TROX-100
Product Categories:-;Intermediates;Miscellaneous;Organics;Biphenyl & Diphenyl ether;Organic Building Blocks;Building Blocks;C9 to C20+;Chemical Synthesis;Oxygen Compounds;Phenols;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Organic Building Blocks;Oxygen Compounds;TRIDIONE;Preservative
Mol File:3380-34-5.mol
Triclosan Structure
Triclosan Chemical Properties
Melting point 56-60 °C(lit.)
Boiling point 290°C(lit.)
density 1.4214 (rough estimate)
refractive index 1.4521 (estimate)
storage temp. Refrigerator
solubility H2O: soluble12g/L at 20°C
pka7.9(at 25℃)
form Solid
color colorless or white
Water Solubility Soluble in ethanol, methanol, diethyl ether and sodium hydroxide solution (1M). Slightly soluble in water.
Merck 14,9657
BRN 2057142
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference3380-34-5(CAS DataBase Reference)
NIST Chemistry ReferenceTriclosan(3380-34-5)
EPA Substance Registry SystemPhenol, 5-chloro-2-(2,4-dichlorophenoxy)- (3380-34-5)
Safety Information
Hazard Codes Xi,N
Risk Statements 36/38-50/53-36/37/38
Safety Statements 26-39-46-60-61-24/25-22-36
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS KO1100000
HazardClass 9
PackingGroup III
HS Code 29095000
Hazardous Substances Data3380-34-5(Hazardous Substances Data)
MSDS Information
SigmaAldrich English
ALFA English
Triclosan Usage And Synthesis
DisinfectantsTriclosan is an efficient broad-spectrum topical antimicrobial disinfectant which is normally white or off-white crystalline powder. It has a slightly phenolic odor. It is insoluble in water but easily soluble in organic solvents and alkali. It has a relative stable chemical property and is heating-resistant and also resistant to acid and alkali hydrolysis without generating any symptoms of the toxicity and environmental pollution. It is internationally recognized as a fungicide variety with specific efficacy. It can kill bacteria such as Staphylococcus aureus, Escherichia coli and fungi such as Candida albicans. It also has an inhibitory effect on the virus (e.g., hepatitis B virus, etc.) while being able to protect the beneficial bacteria. The mechanism of action of triclosan is as below: it is first adsorbed on the bacterial cell wall and then further penetrates through the cell wall and has reaction with the lipid and protein in the cytoplasm, and thus resulting in protein denaturation which further kill the bacteria. Currently it has been widely applied to highly-efficient medicated soap (health soap, health lotion), removing underarm odor (foot aerosol), hand sanitizer, wound disinfectant sprays, medical equipment disinfectants, hygiene cleanser (cream), and air fresheners and refrigerator deodorants and some other daily chemicals. It is also used for the cleaning of the health fabric and the anti-corrosion treatment of plastics. Its high purity version can be added to the toothpaste and mouthwash for treatment of gingivitis, periodontitis and oral ulcers. The State content must not exceed 0.3%.
CarcinogenicityIn 2004, a teacher (Dr. Peter Vikesland) from the Virginia Tech University (US) had found from the experiments that the reaction between the triclosan-containing product and the chlorine-containing tap water containing can generate a substance known as "chloroform aryl", that is, chloroform (chemical name: trichloromethane) which is a colorless, volatile liquid with a special sweetness. Upon exposure to light, it will be oxidized to generate hydrogen chloride and phosgene. It had been once used as an anesthetic. Animal experiments have found that this substance will do harm to the heart and liver with mild teratogenicity and can induce the liver cancer of mice. However, so far no studies on the human carcinogenicity have been reported. For insurance purposes, both the International Cancer Research Centre and the United States have already has the chloroform be listed as suspected carcinogens to the human body.
Toothpaste StandardThe national standard of the toothpaste used in China is the new national standard of toothpaste (GB8372-2008) implemented on February 1, 2009. Compared with the 2001 version of toothpaste standard, the new national standard has been supplemented and adjusted in various aspects. In the new national standard of toothpaste, the prohibited or restricted ingredients include nearly 1,500 kinds, including diethylene glycol and triclosan. The provision of diethylene glycol is that it is not allowed to artificially add it to the raw materials, such as being introduced as impurities. Its content in the toothpaste should not exceed 0.1%. Triclosan were listed as being allowable preservatives but with the usage amount not exceeding 0.3%. The new national standard has ruled that the fluorine content of the fluoride-containing toothpaste should be within the range of 0.04%-0.15%, and the fluoride content should be within the range of 0.05% to 011% for children fluoride-containing toothpaste.
The above information is edited by the chemicalbook of Dai Xiongfeng.
Chemical PropertiesIt is colorless and long needle-like crystals with a melting point being around 54-57.3 ℃ (60-61 ℃). It is slightly soluble in water and soluble in ethanol, acetone, ethyl ether and alkali solution. It has a chloro-phenol odor.
Uses1. It can be used as antiseptic and fungicide and applied to cosmetics, emulsions and resins; also can be used for the manufacture of disinfection medicated soap. The LD50 of mice subject to oral administration of this product is 4g/kg.
2. It can be used for the production of top-grade daily chemical product, the disinfectants of medical instrument as well as diet instrument as well as the preparation of the anti-bacterial, deodorant finishing agent of fabric.
3. It can also be applied to biochemical studies. It is a kind of broad-spectrum antimicrobial agents which inhibit the type II fatty acid synthase (FAS-II) of bacteria and parasites, and also inhibits the mammalian fatty acid synthase (FASN), and may also have anticancer activity
Production method1. Take 2, 4-dichloro-phenol as the raw material; use 2,4-dichloro-phenol to react with potassium hydroxide to generate dichlorophenol potassium which further reacts with 2,5-dichloro-nitrobenzene in the catalysis of copper for generation of 2,4,4-trichloro-2'-nitro diphenyl ether. It is further reduced by iron powder to generate 2, 4, 4-trichloro-2'-amino diphenyl ether, and then further went through diazotization hydrolysis to obtain the product.
2. Take o-methoxyphenol as the raw material: have potassium hydroxide powder reacted with guaiacol to generate guaiacol potassium. Apply reaction between bromobenzene and methoxy ether, together with chlorine for chlorination to obtain 2, 4, 4’-trichloro-2'-methoxydiphenyl ether. Take AICI3 as hydrolysis catalyst to generate 2,4,4'-trichloro-2'-hydroxydiphenyl ether.
Chemical PropertiesSolid
UsesUsed as bacteriostat and preservative for cosmetic and detergent compositions. Antiseptic, disinfectant.
Usestriclosan is a preservative considered to have a low sensitizing potential in leave-on preparations.
DefinitionChEBI: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodo ants as well as in household items such as plastic chopping boards, sports equipment and shoes.
UsesBacteriostat and preservative for cosmetic and detergent preparations.
Brand nameStri-Dex Cleansing Bar (Sterling Health U.S.A.); Stri-Dex Face Wash (Sterling Health U.S.A.).
Triclosan Preparation Products And Raw materials
Raw materialsPotassium hydroxide -->Iron-->Copper-->Bromobenzene-->Diphenyl oxide-->2,4-Dichlorophenol-->Guaiacol-->2,6-Dichlorophenol-->2-Phenoxyaniline
Tag:Triclosan(3380-34-5) Related Product Information
Perchlorate, ClO{|: glass body: double junction electrode: kit AMMONIUM PERCHLORATE Trichlorosilane Ethylbenzene Dimethyl ether Trichloroisocyanuric acid PETROLEUM ETHER Diphenyl ether Phenol Dicofol Trichloroethane Phenol Red Chloroform Trichloroethylene Difluorochloromethane 3-Aminophenol 2-Butoxyethanol Diethyl ether