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Bis(2-ethylhexyl) phthalate Produkt Beschreibung

Bis(2-ethylhexyl) phthalate Struktur
117-81-7
CAS-Nr.
117-81-7
Englisch Name:
Bis(2-ethylhexyl) phthalate
Synonyma:
DOP;Behp;DEHP;daf68;DAF 68;di-sec;NLA-20;Octoil;mollano;Fleximel
CBNumber:
CB8708555
Summenformel:
C24H38O4
Molgewicht:
390.56
MOL-Datei:
117-81-7.mol

Bis(2-ethylhexyl) phthalate Eigenschaften

Schmelzpunkt:
-50 °C
Siedepunkt:
386 °C(lit.)
Dichte
0.985 g/mL at 25 °C(lit.)
Dampfdichte
>16 (vs air)
Dampfdruck
1.2 mm Hg ( 93 °C)
Brechungsindex
n20/D 1.488
Flammpunkt:
405 °F
storage temp. 
2-8°C
Löslichkeit
Miscible with mineral oil and hexane (U.S. EPA, 1985)
Aggregatzustand
Liquid
Farbe
APHA: ≤10
Geruch (Odor)
Very slight, characteristic.
Wasserlöslichkeit
Negligible
FreezingPoint 
<-60℃
Merck 
14,2864
BRN 
1890696
Henry's Law Constant
(x 10-5 atm?m3/mol): 1.1 at 25 °C (calculated, Howard, 1989)
Expositionsgrenzwerte
Potential occupational carcinogen. NIOSH REL: TWA 5, STEL 10, IDLH 5,000; OSHA PEL: TWA 5; ACGIH TLV: TWA 5 (adopted).
CAS Datenbank
117-81-7(CAS DataBase Reference)
NIST chemische Informationen
Bis(2-ethylhexyl)phthalate(117-81-7)
EPA chemische Informationen
1,2-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester(117-81-7)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T,F
R-Sätze: 60-61-39/23/24/25-23/24/25-11
S-Sätze: 53-45-36/37-16
RIDADR  UN 1230 3/PG 2
WGK Germany  1
RTECS-Nr. TI0350000
Selbstentzündungstemperatur 734 °F
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29173400
Giftige Stoffe Daten 117-81-7(Hazardous Substances Data)
Toxizität Acute oral LD50 for guinea pigs 26 gm/kg, mice 30 gm/kg, rats 30,600 mg/kg, rabbits 34 gm/kg (quoted, RTECS, 1985).
Bildanzeige (GHS)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H360 Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. Fertility (Fruchtbarkeit) Kategorie 1 Achtung
H370 Schädigt die Organe. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 1 Achtung P260, P264, P270, P307+P311, P321,P405, P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P311 GIFTINFORMATIONSZENTRUM/Arzt anrufen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.

Bis(2-ethylhexyl) phthalate Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

FARBLOSE BIS LEICHT GEFäRBTE, VISKOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.

CHEMISCHE GEFAHREN

Zersetzung beim Erhitzen unter Bildung reizender Rauche. Reagiert mit starken Oxidationsmitteln, Säuren, Alkalien und Nitraten.

ARBEITSPLATZGRENZWERTE

TLV: 5 mg/m?(als TWA); Krebskategorie A3 (bestätigte krebserzeugende Wirkung beim Tier mit unbekannter Bedeutung für den Menschen); (ACGIH 2005).
MAK: 10 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(8); Krebserzeugend Kategorie 4; Schwangerschaft: Gruppe C; (DFG 2005).

AUFNAHMEWEGE

Aufnahme in den Körper durch Inhalation, über die Haut und durch Verschlucken.

INHALATIONSGEFAHREN

Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Versprühen schnell erreicht werden.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen und die Atemwege.

WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION

Möglich sind Auswirkungen auf die Hoden. Tierversuche zeigen, dass die Substanz möglicherweise fruchtbarkeitsschädigend oder entwicklungsschädigend wirken kann.

LECKAGE

Zündquellen entfernen. Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Chemikalienschutzanzug.

R-Sätze Betriebsanweisung:

R60:Kann die Fortpflanzungsfähigkeit beeinträchtigen.
R61:Kann das Kind im Mutterleib schädigen.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.

S-Sätze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.

Chemische Eigenschaften

Bis(2-ethylhexyl)phthalate is a colorless liquid with a slight odor. It is miscible with mineral oil and hexane, and soluble in most organic solvents. Bis(2-ethylhexyl)phthalate is insoluble in water (NTP, 1994a).

Verwenden

Dialkyl phthalate ester plasticizer used to import softness and flexibility to PVC products.

Verwenden

As plasticizer in PVC applications and flexible vinyls.

Verwenden

Bis(2-ethylhexyl) phthalate is used in vacuum pumps and was formerly employed as a miticide.

Verwenden

Bis(2-ethylhexyl) phthalate, known by a variety of other names and usually abbreviated DEHP, was patented in 1950 and first used as vacuum pump oil. But since then, it has become the most widely used plasticizer for poly(vinyl chloride) (PVC) and other plastics. Recently, relatively high levels of DEHP have been found in foods, especially foods high in oils and fats. The U.S. Food and Drug Administration now restricts its use in packaging materials to water-based foods. The European Commission has banned the use of DEHP and other phthalates in PVC toys.
Di(2-ethylhexyl)phthalate (DEHP) is a benzenedicarboxilate ester which is the most widely used plasticizer to soften resins. DEHP is hydrolyzed into what many believe to be its toxic metabolite, mono(2-ethylhexyl)phthalate (MEHP), by lipase enzymes in the gastrointestinal tract.

Definition

ChEBI: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.

Allgemeine Beschreibung

Colorless to pale yellow oily liquid. Nearly odorless.

Air & Water Reaktionen

Insoluble in water.

Reaktivität anzeigen

Bis(2-ethylhexyl) phthalate reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing with alkali metals and hydrides. Incompatible with nitrates .

Health Hazard

Inhalation can cause nausea and irritation of nose and throat. Contact of liquid with eyes or skin causes irritation. Ingestion can cause abdominal cramps, nausea and diarrhea.

Health Hazard

The acute oral toxicity is of extremelylow order. The oral LD50 value in miceis in the range 30,000 mg/kg. Ingestion ofabout 10 mL of the liquid may produce gas trointestinal pain, hypermotility, and diar rhea in humans. Chronic administration byoral route did not produce any adverseeffect in animals. A dose of 100 mg/kg/dayproduced increased liver and kidney weight,as well as retardation of growth in dogs.Mice given diets containing 12,000 ppm ofdiethylhexyl phthalate for 40 weeks devel oped renal hyperplasia (Ward et al. 1988).There was no evidence of renal carcino genicity. Oral administration, however, pro duced tumors in livers in the laboratoryanimals. It is a suspected cancer-causingagent, and there is sufficient evidence of itscarcinogenicity in animals. Such evidence inhumans, however, is lacking
Rock and co-workers (1988) reported theinteraction of diethylhexyl phthalate withblood during storage in PVC plastic containers. The plasticizer is leached into theplasma and converted to mono(2-ethylhexyl)phthalate by a plasma enzyme. At a levelof >125 mg/mL in the blood mono(2-ethyl hexyl) phthalate produced a 50% decrease inheart rate and blood pressure in rats.

Chemische Reaktivität

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Sicherheitsprofil

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Experimental teratogenic data. Other experimental reproductive effects. Poison by intravenous route. Human systemic effects by ingestion: gastrointestinal tract effects. A mild skin and eye irritant. When heated to decomposition it emits acrid smoke.

mögliche Exposition

Bis(2-ethylhexyl)phthalate is primarily used as one of several plasticizers in polyvinyl chloride resins used for fabricating flexible vinyl products. It has also been reported as being used as a replacement for polychlorinated biphenyls (PCBs) in dielectric fluids for electric capacitors and in vacuum pumps (NTP, 1994a; Merck, 1989). The primary stationary sources that have reported emissions of bis(2-ethylhexyl)phthalate in California are furniture and fixtures manufacturing, and lumber and wood products manufacturing (ARB, 1997b).

Carcinogenicity

Di(2-ethylhexyl) phthalate (DEHP) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Source

MCLG: zero; MCL: 6 μg/L. In addition, a DWEL of 700 μg/L was recommended (U.S. EPA, 2000).
Detected in distilled water-soluble fractions of new and used motor oil at concentrations of 17–21 and ND-1.2 μg/L, respectively (Chen et al., 1994). Also may leach from plastic products used in analytical laboratories (e.g., tubing, containers).

Environmental Fate

Biological. Bis(2-ethylhexyl) phthalate degraded in both amended and unamended calcareous soils from New Mexico. After 146 d, 76 to 93% degraded (mineralized) to carbon dioxide. No other metabolites were detected (Fairbanks et al., 1985). In a 56-d experiment, [14C]bis(2- ethylhexyl) phthalate applied to soil-water suspensions under aerobic and anaerobic conditions gave 14CO2 yields of 11.6 and 8.1%, respectively (Scheunert et al., 1987).
When bis(2-ethylhexyl) phthalate was statically incubated in the dark at 25 °C with yeast extract and settled domestic wastewater inoculum, no degradation was observed after 7 d. In a 21-d period, however, gradual adaptation did occur resulting in 95 and 93% losses at concentrations of 5 and 10 mg/L, respectively (Tabak et al., 1981).
Half-lives of 19 h and 4–5 wk were reported for bis(2-ethylhexyl) phthalate in activated sludge and river water, respectively (Saeger and Tucker, 1976). In sludge-amended agricultural soil, bis(2-ethylhexyl) phthalate (initial concentration 4.1 nmol/g) degraded at a rate of 25.6 pmol/g·day via the intermediate o-phthalic acid. Despite the presence of microorganisms capable of degrading bis(2-ethylhexyl) phthalate, >40% of the bis(2-ethylhexyl) phthalate added was not mineralized after 1 yr (Roslev et al., 1998). Aerobic degradation of bis(2-ethylhexyl) phthalate by acclimated soil and activated sewage sludge microbes was studied using an acclimated shake flask CO2 evolution test. After 28 d, loss of bis(2-ethylhexyl) phthalate (primary degradation) was >99%, with a lag phase of 2.7 d, and ultimate biodegradation (CO2 evolution) was 86%. The half-life under these conditions was 4.55 d (Sugatt et al., 1984).
In the presence of suspended natural populations from unpolluted aquatic systems, the secondorder microbial transformation rate constant determined in the laboratory was reported to be 4.2 ± 0.7 x 10-15 L/organism?h (Steen, 1991). Using the modified Sturm test, >80% of bis(2-ethylhexyl) phthalate mineralized to carbon dioxide in 28 d (Scholz et al., 1997).
Surface Water. In laboratory experiments, the extrapolated volatilization half-life of bis(2- ethylhexyl) phthalate in a stirred water vessel (outer dimensions 22 x 10 x 21 cm) conducted at 22 and 30 °C and an air flow rate of 0.20 m/sec is 3,500 h (Kl?pffer et al., 1982).
Photolytic. The estimated photolytic half-life of bis(2-ethylhexyl) phthalate in water is 143 d (Wolfe et al., 1980).
Chemical/Physical. Hydrolyzes in water to o-phthalic acid (via the intermediate 2-ethyl-hexyl hydrogen phthalate) and 2-ethylhexyl alcohol (Kollig, 1993; Wolfe et al., 1980). Although no pH value was given, the reported hydrolysis rate constant under alkaline conditions is 1,400/M?yr (Ellington et al., 1993; Kollig, 1993). A second-order rate constant of 1.1 x 10-4/M?sec was reported for the hydrolysis bis(2-ethylhexyl) phthalate at 30 °C and pH 8 (Wolfe et al., 1980). Kl?pffer et al. (1982) estimated an evaporation half-life of approximately 140 d from a 21-cm deep vessel.

Stoffwechsel

Bis(2-ethylhexyl) phthalate is metabolized in fish by enzymatic hydrolysis to mono-2-ethylhexyl phthalate, phthalic acid, and glucuronides of these compounds (Stalling et al., 1973).

läuterung methode

Wash the ester with Na2CO3 solution, then shake it with water. After the resulting emulsion has been broken by adding ether, the ethereal solution is washed twice with water, dried (CaCl2), and evaporated. The residual liquid is distilled several times under reduced pressure, then stored in a vacuum desiccator over P2O5 [French & Singer J Chem Soc 1424 1956]. [Beilstein 9 IV 3184.]

Verordnung (Regulations)

Consumer Product Safety Commission (CPSC)
A voluntary standard provides that pacifiers, rattles, and teethers shall not intentionally contain DEHP.
It is unlawful for any person to manufacture for sale, offer for sale, distribute in commerce, or import into the United States any children’s toy or child-care article that contains DEHP at concentrations of more than 0.1%.
Environmental Protection Agency (EPA)
Clean Air Act
National Emissions Standards for Hazardous Air Pollutants: Listed as a hazardous air pollutant. New Source Performance Standards: Manufacture of DEHP is subject to certain provisions for the control of volatile organic compound emissions.
Clean Water Act
Effluent Guidelines: Phthalate esters are listed as toxic pollutants. Water Quality Criteria: Based on fish or shellfish and water consumption = 1.2 μg/L; based on fish or shellfish consumption only = 2.2 μg/L.
Comprehensive Environmental Response, Compensation, and Liability Act Reportable quantity (RQ) = 100 lb.
Emergency Planning and Community Right-To-Know Act Toxics Release Inventory: Listed substance subject to reporting requirements.
Resource Conservation and Recovery Act Listed Hazardous Waste: Waste code for which the listing is based wholly or partly on the presence of DEHP = U028. Listed as a hazardous constituent of waste.
Safe Drinking Water Act
Maximum contaminant level (MCL) = 0.006 mg/L.
Food and Drug Administration (FDA)
Limitations on the use of DEHP in basic components of single and repeated use food contact surfaces are prescribed in 21 CFR 177.
Occupational Safety and Health Administration (OSHA)
While this section accurately identifies OSHA’s legally enforceable PELs for this substance in 2010, specific PELs may not reflect the more current studies and may not adequately protect workers. Permissible exposure limit (PEL) = 5 mg/m3.

Bis(2-ethylhexyl) phthalate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Bis(2-ethylhexyl) phthalate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 259)Lieferanten
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Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21714 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Chemson Industrial (Shanghai) Co., Ltd.
86-21-65208861-ext8007
86-21-65180813 sales1@chemson.com.cn CHINA 117 58
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sales@coreychem.com CHINA 30002 58
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86-21-51086038
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