4-Butylresorcinol
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- CAS-Nr.
- 18979-61-8
- Englisch Name:
- 4-Butylresorcinol
- Synonyma:
- Butylresorcinol;4-N-BUTYLRESORCINOL;4-Butylbenzene-1,3-diol;2,4-DIHYDROXY-N-BUTYL BENZEN;Rucinol;N-BUTYLRESEOCINOL;4-Butylresorcinol;Serine Impurity 12;Resorcinol, 4-butyl-;4-Butylresorcinol >
- CBNumber:
- CB9361328
- Summenformel:
- C10H14O2
- Molgewicht:
- 166.22
- MOL-Datei:
- 18979-61-8.mol
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4-Butylresorcinol Eigenschaften
- Schmelzpunkt:
- 50.0 to 55.0 °C
- Siedepunkt:
- 166°C/7mmHg(lit.)
- Dichte
- 1.092±0.06 g/cm3(Predicted)
- Dampfdruck
- 0.041Pa at 25℃
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- DMSO : 150 mg/mL (902.42 mM)
- Aggregatzustand
- Powder
- pka
- 9.95±0.18(Predicted)
- Farbe
- white to pale yellow powder
- Geruch (Odor)
- Characteristic
- InChI
- InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3
- InChIKey
- CSHZYWUPJWVTMQ-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=C(CCCC)C(O)=C1
- LogP
- 2.8 at 24℃ and pH7
- Oberflächenspannung
- 17.8mN/m at 1g/L and 20℃
- CAS Datenbank
- 18979-61-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| RTECS-Nr. |
VH0420000 |
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| HS Code |
2907290090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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4-Butylresorcinol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-n-butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. It may be used to decrease skin irritation and is also known to inhibit melanin production.
Verwenden
4-Butylresorcinol is considered a potential Cytochrome P450 inhibitor. It can cause hypopigmentation due to its direct inhibition of tyrosinase.
Application
Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel′s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
Biologische Aktivität
Glutathione reductase IGR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the process is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, citrate synthase, EF hands, hemoglobins, lipocalins, and α/β hydrolases. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.
Mechanism of action
The mechanism of action of 4-butylresorcinol depigmentation is through inhibition of tyrosinase and tyrosinase-related protein-1 (TRP-1)
[1].
4-Butylresorcinol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Butylresorcinol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 492)Lieferanten
18979-61-8()Verwandte Suche:
- 4-BUTYLRESORCINOL,98+%
- 4-Butylresorcinol
- 1,3-Benzenediol,4-butyl-
- 2,4-DIHYDROXY-N-BUTYL BENZENE
- 4-phenylbutane-1,3-diol
- 2,4-Dihydroxy-n-bytyl benzen
- 4-06-00-06003 (Beilstein Handbook Reference)
- N-BUTYLRESEOCINOL
- Nano Liposomal N-BUTYLRESEOCINOL
- 2,4-Dihydroxy-n-bytyl benzene
- 4-BUTYLBENZENE-1 3-DIOL(COSMOBRITE)
- 4-n-Butylresorcinol, Rucinol
- Nano-Liposomal 4-Butylresorcinol
- 4-Butylresorcinol >
- TIANFU-CHEM 18979-61-8
- KOPCINOL – N-Butyl Resorcinol
- 4-Butylbenzene-1,3-diol
- 4-N-BUTYLRESORCINOL
- 2,4-DIHYDROXY-N-BUTYL BENZEN
- Butylresorcinol
- 4-Butylresorcinol (Butylresorcinol)
- low price 18979-61-8 On Sale4-N-Butylresorcinol exporter
- 2-Amino-5-chlorobenzophenone 719-59-5
- 4-Butyl Resorcinol (4-BR)
- Resorcinol, 4-butyl-
- Serine Impurity 12
- Rucinol
- 4-Butylresorcinol
CAS
- 4-Butylresorcinol/ 4-N-Butylresorcinol
- 18979-61-8
- Benzene derivates
- Miscellaneous
- pharmaceutical
- 18979-61-8
