Chloramine-T
- CAS No.
- 127-65-1
- Chemical Name:
- Chloramine-T
- Synonyms
- CHLORAMINE T;Tosylchloramide sodium;SodiuM chloro(tosyl)aMide;halamid;chlorazan;MI 9;NF X;anexol;GANSIL;clorina
- CBNumber:
- CB7344990
- Molecular Formula:
- C7H7ClNNaO2S
- Molecular Weight:
- 227.64
- MDL Number:
- MFCD00000522
- MOL File:
- 127-65-1.mol
| Melting point | 167-170 °C(lit.) |
|---|---|
| Density | 1.401[at 20℃] |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Sealed in dry,2-8°C |
| solubility | H2O: >100 mg/mL |
| pka | 0.39[at 20 ℃] |
| Water Solubility | 150g/L at 25℃ |
| Stability | Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air. |
| InChI | InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1 |
| InChIKey | VDQQXEISLMTGAB-UHFFFAOYSA-N |
| SMILES | S(=O)(=O)(N(Cl)[Na])C1C=CC(C)=CC=1 |
| LogP | -1.3 at 20℃ |
| FDA 21 CFR | 556.118 |
| Indirect Additives used in Food Contact Substances | SODIUM P-TOLUENESULFONCHLOROAMIDE |
| CAS DataBase Reference | 127-65-1(CAS DataBase Reference) |
| EWG's Food Scores | 1-6 |
| FDA UNII | 328AS34YM6 |
| ATC code | D08AX04 |
| EPA Substance Registry System | Chloramine T (127-65-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | C,Xn |
| Risk Statements | 22-31-34-42 |
| Safety Statements | 22-26-36/37/39-45-7-1/2 |
| RIDADR | UN 3263 8/PG 3 |
| WGK Germany | 2 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29242990 |
Chloramine-T price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S470155 | AKTIVIN AldrichCPR | 127-65-1 | 1G | $179 | 2024-03-01 | Buy |
| Matrix Scientific | 099856 | Sodium chloro(tosyl)amide 95+% | 127-65-1 | 100g | $285 | 2021-12-16 | Buy |
| ChemScene | CS-4435 | Chloramine-T ≥98.0% | 127-65-1 | 500mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-4435 | Chloramine-T ≥98.0% | 127-65-1 | 1g | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 099856 | Sodium chloro(tosyl)amide 95+% | 127-65-1 | 25g | $118 | 2021-12-16 | Buy |
Chloramine-T Chemical Properties,Uses,Production
Description
The sodium salt of p-toluenesulfochloramide, commonly known as chloramine-T, exerts strong oxidizing action in both acidic and alkaline media and thus has been widely used for the oxidimetric determination of a large number of inorganic and organic substances.
Oxidation of some aldehydes by chloramine-T has been reported to occur quantitatively in an alkaline solution, giving the corresponding acid as the end product. Both direct and indirect methods have been carried out to estimate aldehydes by chloramine-T. Chloramine-T (CAT) is also commonly used in radiolabeling bioactive molecules by halogenation. CAT is used to release radioactive elemental iodine by oxidation of its salts. Unfortunately, CAT is a strong oxidizing agent and can cause significant damage to peptides and proteins. This may lower the yield of the iodination reaction and may produce undesirable side products[1-2].
Chemical Properties
white or yellow powder with a chlorine-like odour
Uses
sterilizer, antiseptic, disinfectant, and chemical reagent in the medical and pharmaceutical fields.
Uses
antiseptic, disinfestant, antiproliferative
Uses
This disinfectant is for external use only, it can exterminate bacteria, viruses, fungi, spore. The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced by Chloramine-T solution. Apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.
Definition
ChEBI: An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Flammability and Explosibility
Not classified
Safety Profile
Poison by parenteral and intravenous routes. Human mutagenic data reported. When heated to decomposition it emits toxic fumes of Cl-, SOx, Na2O, and NOx. See also SULFONATES and CHLORIDES.
Synthesis
Chloramine-T is prepared
in 75 – 95 % yield by passing chlorine into a
sodium hydroxide solution of p-toluenesulfonamide. It is a strong electrolyte in acid
solution and a good oxidizing agent in base. It is
fairly soluble in water, and practically insoluble
in benzene, chloroform, and ether. The compound reacts readily with mustard gas to yield
a harmless crystalline sulfimide; chloramine-T
derivatives are being studied as protective agents
against poison gas.
References
[1] M. C. Agrawal, S. P. Mushran. "Mechanism of Oxidation of some Aliphatic Aldehydes by Chloramine-T." Zeitschrift für Naturforschung B 20 1 (1972): 401–404.
[2] B M Tashtoush. "Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques." Analytical biochemistry 288 1 (2001): 16–21.
Chloramine-T Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shouguang Nuomeng Chemical Co Ltd. | 536-5119508 18363669993; | export@nuomengchem.com | China | 44 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 | sarah@tnjone.com | China | 874 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
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- Aug 18，2022
View Lastest Price from Chloramine-T manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | Chloramine-T
127-65-1
|
US $5.00 / kg | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-03-27 | Chloramine-T
127-65-1
|
US $0.00 / KG | 1KG | 99% | 2000KG | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2023-12-26 | Chloramine-T, Chloramine T trihydrate, N-Chloro-P-Toluenesulfonamide Sodium Salt
127-65-1
|
US $4900.00 / T | 1KG | 98% Min. | 200 tons per month | Shouguang Nuomeng Chemical Co Ltd. |
-
- Chloramine-T
127-65-1
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Chloramine-T
127-65-1
- US $0.00 / KG
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Chloramine-T, Chloramine T trihydrate, N-Chloro-P-Toluenesulfonamide Sodium Salt
127-65-1
- US $4900.00 / T
- 98% Min.
- Shouguang Nuomeng Chemical Co Ltd.