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Overview Toxicity Usage limits Chemical Properties Application Production method
Chemical Name:
NERAL;LEMSYN;CITRAL;lemsyngb;LEMAROME;GERANIAL;b-citral;citral b;a-citral;gerznial
Molecular Formula:
Formula Weight:
MOL File:

Citral Properties

Melting point:
Boiling point:
229 °C(lit.)
0.888 g/mL at 25 °C(lit.)
vapor density 
5 (vs air)
vapor pressure 
0.2 mm Hg ( 200 °C)
refractive index 
n20/D 1.488(lit.)
2303 | CITRAL
Flash point:
215 °F
storage temp. 
colorless to light yellow
explosive limit
Water Solubility 
Stable. but readily isomerizes. Incompatible with alkalies, strong oxidizing agents, strong acids. Combustible. Air and light sensitive.
CAS DataBase Reference
5392-40-5(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
2,6-Octadienal, 3,7-dimethyl-(5392-40-5)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  38-43
Safety Statements  24/25-37
RIDADR  1760
WGK Germany  1
RTECS  RG5075000
HazardClass  8
PackingGroup  III
Hazardous Substances Data 5392-40-5(Hazardous Substances Data)
Toxicity LD50 orally in rats: 4.96 g/kg (Opdyke)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).
P308+P313 IF exposed or concerned: Get medical advice/attention.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Citral price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 15861 Citral analytical standard 5392-40-5 1ml $49.4 2018-11-13 Buy
Sigma-Aldrich 43318 Citral analytical standard 5392-40-5 1ml $51.5 2018-11-13 Buy
TCI Chemical D0762 Citral (cis- and trans- mixture) >98.0%(GC) 5392-40-5 25mL $26 2017-11-08 Buy
Alfa Aesar A16169 Citral, cis + trans, 95% 5392-40-5 100g $28.5 2018-11-13 Buy
Alfa Aesar A16169 Citral, cis + trans, 95% 5392-40-5 50g $19.4 2018-11-13 Buy

Citral Chemical Properties,Uses,Production


Citral (C10H16O), also called 3,7-dimethyl-2,6-octadienal, a pale yellow liquid, with a strong lemon odour, that occurs in the essential oils of plants. It is insoluble in water but soluble in ethanol (ethyl alcohol), diethyl ether, and mineral oil. It is used in perfumes and flavourings and in the manufacture of other chemicals. Chemically, citral is a mixture of two aldehydes that have the same molecular formula but different structures.
Content analysis
Accurately weigh about 1g of the sample, and then perform the determination by the hydroxylamine method (OT-7, method one) used in aldehyde and ketone determination. The equivalent factor (e) in the calculation is 76.12.


ADI 0~0.5mg/kg (FAO/WHO, 1994-). LD50 4960 mg/kg (rat, oral); MNL 500 mg/kg.

Usage limits

FEMA (mg/kg): soft drinks 9.2; cold drinks 23; candy 41; baked goods 43; chewing gums 170

Chemical Properties

Colorless or slightly yellow liquid; strong lemon flavor; no optical rotation; boiling point 228 °C; flash point 92 °C;
There are cis and trans two isomers. With sodium bisulfite treatment, cis isomer solubility is minimal, while the trans isomer solubility is very large, so the two isomers can be separated.
Cis citral: relative density (d20) 0.8898, refractive index (nD20) 1.4891, boiling point 118~119℃ (2666Pa).
Trans citral: relative density (d20) 0.8888, refractive index (nD20) 1.4891, boiling point 117~118℃ (2666Pa).
Soluble in non-volatile oils, volatile oils, propylene glycol and ethanol; insoluble in glycerol and water; unstable in alkaline and strong acids
Natural products present in lemon grass oil (70% to 80%), litsea cubeba oil (about 70%), lemon oil, white lemon oil, citrus leaf oil and so on.


Citral is an artificial flavor permitted to use in China, which can be used to prepare strawberries, apples, apricots, sweet orange, lemon and other fruit-based flavors. According to normal production needs, the citrals amount used in chewing gums is 1.70mg/kg; baked goods 43mg/kg; candy 41mg/kg; cold drinks 23mg/kg; soft drinks 9.2mg/kg.
It is also widely used in dishwashing detergents and the flavoring agents of soap and toilet water. Citral can be used as the raw material to synthesize ionone, methyl ionone and dihydro damascene. As organic raw material, it can also be reduced to generate citronellol, nerol alcohol and geraniol, and be converted into lemonile. In the pharmaceutical industry, it can be used for the manufacture of vitamin A and E, and also as the raw material of chlorophyll.

Production method

Citral natural exists in the litsea cubeba oil (about 80%), lemon grass oil (80%), clove basil oil (65%), sour lemon oil (35%) and lemon oil. In industry, citral can be derived from natural essential oils, or be prepared by chemical.
Synthesis based on methyl heptenone as raw material
Ethoxyacetylene magnesium bromide and methyl heptenone performed condensation reaction to form 3,7-dimethyl-1-ethoxy-3-hydroxy-6-octene-1-yne, which was then partly hydrogenated in the presence of catalysis to generate enol ether. And the enol ether was then hydrolyzed with phosphoric acid and dehydrated to obtain citral, with a yield of 68% calculated by methyl heptenone. In addition, acetylene and methyl heptenone could perform condensation reaction to form dehydrogenation linalool, which was then rearranged in the presence of silicon sulfone catalysis at 140~150 °C in inert solvent to get citral.
Derived from litsea cubeba oil (which is the main method to product citral in China)
Add 30 kg of cubeba oil containing about 75% of citral into a mixture under fully stirring, which was prepared with 18 kg of sodium bicarbonate, 38 kg of sodium sulfite and about 165 kg of water, and then continually stir for 5 to 6 h at room temperature. After standing overnight for stratification, the lower citral precipitated in the form of adduct. And the adduct was then washed with a small amount of toluene to remove oil and dried. And then add 10% sodium hydroxide solution to decompose citral at room temperature, and extract it with benzene. The extract was first distilled at atmospheric pressure (80-82°C) to recover benzene and then distilled under reduced pressure to collect fractions of 110-111°C (1.47kPa) to obtain pure product of 98% citral in an amount of about 15 to 16 kg.

Chemical Properties

mobile light yellow liquid with a lemon-like smell


Citral is an anti-microbial agent found in plants with antibacterial activity against some food pathogens. It is also a fragrance compound with a distinct lemon scent.

General Description

A clear yellow colored liquid with a lemon-like odor. Less dense than water and insoluble in water. Toxic by ingestion. Used to make other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Citral is an aldehyde. Aldehydes are frequently involved in self-condensation or polymerization reactions. These reactions are exothermic; they are often catalyzed by acid. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction). The addition of stabilizers (antioxidants) to shipments of aldehydes retards autoxidation. Citral can react with alkalis and strong acids. Citral can readily isomerize.

Fire Hazard

Citral is combustible.

Contact allergens

Citral is an aldehyde fragrance and flavoring ingredient, a blend of isomers cis (Neral) and trans (geranial). As a fragrance allergen, citral has to be mentioned by name in cosmetics within the EU.

Citral Preparation Products And Raw materials

Raw materials

Preparation Products

Citral Suppliers

Global( 199)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3218 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32764 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1465 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3625 58
Jiangxi Baolin Natural Spices Co.Ltd. 0796-8102348 13576833965 13576827225
0796-8116585 China 119 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40399 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30308 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 China 24654 81
Beijing dtftchem Technology Co., Ltd. 13651141086; 86(10)60275028、60275820
86 (10) 60270825 China 3433 62

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