트리메틸클로로실란
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트리메틸클로로실란 속성
- 녹는점
- −40 °C(lit.)
- 끓는 점
- 57 °C(lit.)
- 밀도
- 0.857 g/mL at 25 °C
- 증기 밀도
- 3.7 (vs air)
- 증기압
- 100 mm Hg ( 25 °C)
- 굴절률
- n
20/D 1.500
- 인화점
- 104 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 에테르, 벤젠, 디에틸에테르 및 퍼클로로에틸렌과 혼합 가능.
- 물리적 상태
- 액체
- Specific Gravity
- 0.8536 (27℃)
- 색상
- 무색의
- 폭발한계
- 1.5-46%(V)
- 수용성
- 물과 반응
- Hydrolytic Sensitivity
- 8: reacts rapidly with moisture, water, protic solvents
- 감도
- Moisture Sensitive
- BRN
- 1209232
- 안정성
- 안정적인. 인화성이 높으며 인화점이 낮습니다. 물과 격렬하게 반응함. 물, 습기, 강산화제, 강산, 강염기, 알데히드, 알코올, 아민, 에스테르, 케톤과 호환되지 않습니다.
- InChIKey
- IJOOHPMOJXWVHK-UHFFFAOYSA-N
- CAS 데이터베이스
- 75-77-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T,F,C,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21-36/38-34-21-14-11-37-35-19-40-10-67-20/21/22-52 | ||
안전지침서 | 26-36/37/39-45-16-36/37-7/9 | ||
유엔번호(UN No.) | UN 2924 3/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | VV2710000 | ||
F 고인화성물질 | 10-21 | ||
자연 발화 온도 | 752 °F | ||
위험 참고 사항 | Highly Flammable/Corrosive/Moisture Sensitive | ||
TSCA | Yes | ||
위험 등급 | 3 | ||
포장분류 | II | ||
HS 번호 | 29310095 | ||
유해 물질 데이터 | 75-77-4(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 4868 mg/kg LD50 dermal Rabbit 1530 mg/kg | ||
기존화학 물질 | KE-05939 |
트리메틸클로로실란 C화학적 특성, 용도, 생산
화학적 성질
Trimethylchlorosilane is a colorless fuming liquid with a pungent odor. Readily hydrolyzed with liberation of hydrogen chloride; soluble in benzene, ether and perchloroethylene. Chlorotrimethylsilane is a chloro-organosilane compound mainly used for silylation reactions.화학 반응
Related to the epoxide ring opening, TMSCl also mediates some cyclopropane ring opening reactions. For example, treatment of 1-aceto-2,2-dimethylcyclopropane with TMSCl and sodium chloride in acetonitrile at 55°C for 24 h generated 5-chloro-5-methyl-2-hexanone in 84% yield (eq 39).When sodium iodide was employed to replace sodium chloride, iodotrimethylsilane generated in situ, and the reaction completed under more facile conditions (rt and 12 h). Interestingly, the dominant product is 5-iodo-4,4-dimethyl-2-pentanone (eq 40), arising from iodide attacking at the less hindered secondary methylene carbon, instead of the quaternary dimethylmethylene carbon.용도
Chlorotrimethylsilane is a typical Silane Blocking Agent, which can protect or deprotect functional groups selectively. It have been used in the preparation of volatile derivatives of a wide range of compounds for GC analysis, and used for silylation and as a protection group in the process of various organic synthesis. It is used in the production of trimethylsilyl halides, pseudohalides and various organic silicon compounds. It is also used to produce hexamethyldisilane by reduction.정의
ChEBI: Chlorotrimethylsilane is a silyl chloride consisting of a central silicon atom covalently bound to one chloro and three methyl groups. Chlorotrimethylsilane is a derivatisation agent used in gas chromatography/mass spectrometry applications. It has a role as a chromatographic reagent.일반 설명
Trimethylchlorosilane appears as a colorless fuming liquid with a pungent odor. Boiling point 135° F, Flash point -18°F. Density 0.854g/cm3. The vapor and liquid may cause burns. Vapors are heavier than air.반응 프로필
Chlorotrimethylsilane reacts vigorously and exothermically with water to produce hydrogen chloride.건강위험
Similar to other silanes. Toxicity is rated high for inhalation, ingestion and local irritation. May cause death or permanent injury after a very short exposure to small quantities.화재위험
Violent reaction with water. Toxic and irritating hydrogen chloride and phosgene may be formed in fires. Difficult to extinguish, re-ignition may occur. Flashback along vapor trail may occur. Containers may explode in fire. Vapor may explode if ignited in enclosed area. When heated to decomposition or on contact with acids or acid fumes, chloride fumes are emitted. Reacts with surface moisture, releasing hydrogen chloride, which will corrode common metals and form flammable hydrogen gas. Avoid contact with water; Chlorotrimethylsilane readily hydrolyzes, liberating hydrochloric acid. Hazardous polymerization may not occur.Safety Profile
Poison by ingestion and skin contact. Moderately toxic by inhalation and intraperitoneal routes. A corrosive irritant to skin, eyes, and mucous membranes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. A flammable liquid and very dangerous fire hazard when exposed to heat or flame. Violent reaction with water or hexafluoroisopropylideneamino lithium, A preparative hazard. To fight fire, use foam, alcohol foam, fog. When heated to decomposition it emits toxic fumes of Cl-. An intermediate in the production of silicones. See also CHLOROSILASES.잠재적 노출
Trimethylchlorosilane is used as an intermediate to make silicone products, including lubricants운송 방법
UN1298 Trimethylchlorosilane, Hazard Class: 3; Labels: 3-Flammable liquid, 8-Corrosive material.Purification Methods
Likely impurities are other chlorinated methylsilanes and tetrachlorosilane (b 57.6o), some of which can form azeotropes. To avoid the latter, very efficient fractional distillation is required. It has been fractionated through a 12 plate glass helices-packed column with only the heart-cut material being used. It has also been fractionated through a 90cm, 19mm diameter Stedman column (p 11). Purify it by redistilling from CaH2 before use. [Sauer et al. J Am Chem Soc 70, 4254 1948, Sauer & Hadsell J Am Chem Soc 70 4258 1948, Langer et al. J Org Chem 23 50 1958, Beilstein 4 IV 4007.] FLAMMABLE and CORROSIVE.비 호환성
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Chlorosilanes react vigorously with bases and both organic and inorganic acids generating toxic and/or flammable gases. Chlorosilanes react with water, moist air, or steam to produce heat and toxic, corrosive fumes of hydrogen chloride. They may also produce flammable gaseous hydrogen. Attacks metals in the presence of moisture. Vigorous reaction with aluminum powder.폐기물 처리
Do not discharge into drains or sewers. Use a licensed disposal contractor to an approved landfill. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office for guidance on acceptable disposal practices. The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material’s impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.트리메틸클로로실란 준비 용품 및 원자재
원자재
준비 용품
6-IODO-PYRIDINE-2-CARBOXYLIC ACID
알릴트리메틸실란
ETHYL 2,4-DIMETHYLQUINOLINE-3-CARBOXYLATE
5-FLUORO-2-PICOLINIC ACID
BIS(TRIMETHYLSILYL)PEROXIDE
(트리 플루오로 메틸) 트리메틸 실란
ROKITAMYCIN
ETHYL 2-(CHLOROMETHYL)-4-METHYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE
1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE
테가퍼
헥사메틸다이사이록산
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-phenylacetic acid
4-AMINO-2,6-DIFLUORO-BENZALDEHYDE
Trimethylsilylacetylene
아지도트리메틸실란
4'-Iodoacetophenone
ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE
METHYL 2-(CHLOROMETHYL)-4-METHYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE
(2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
Rhodanine-3-acetic acid
Bis(trimethylsilyl)acetylene
ETHYL 2-(CHLOROMETHYL)-4-PHENYLQUINOLINE-3-CARBOXYLATE HYDROCHLORIDE
Cefoperazone
Thiophene-2-ethylamine
트리스(트리메틸실릴)실란
6-CYANONICOTINIC ACID
2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE
5-BROMO-3-CHLORO-2-PYRIDINONE
Aniracetam
Thiazole-4-carboxaldehyde
2-ETHYL-4-METHYLQUINOLINE-3-CARBOXYLIC ACID
2,4-DIMETHYLQUINOLINE-3-CARBOXYLIC ACID
트리메틸에톡시실란
N,O-비스(트리메틸시릴)아세트아마이드
1-(2,4-DIMETHYLQUINOLIN-3-YL)ETHANONE HYDROCHLORIDE
2,4-DIMETHOXYPHENETHYLAMINE
7-Aminocephalosporanic acid
5-BROMO-3-FLUORO-2-PYRIDINONE
헥사메틸다이실라잔
Pyridine sulfur trioxide
트리메틸클로로실란 공급 업체
글로벌( 632)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Hangzhou Bayee Chemical Co., Ltd. | 0086-571-86990109 |
rachelhoo@bayeechem.com | China | 104 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com |
jocelynpan@zjarts.com | CHINA | 993 | 58 |
Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 559 | 58 |