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L-Valin Produkt Beschreibung

CAS-Nr.72-18-4
Bezeichnung:L-Valin
Englisch Name:L-Valine
Synonyma:
L-VLA;Valin;L-Val;VALINE;2,3-D2);H-VAL-OH;L-VALINE;L-Val-OH;NSC 76038;VALINE, L-
CBNumber:CB3381690
Summenformel:C5H11NO2
Molgewicht:117.15
MOL-Datei:72-18-4.mol
L-Valin physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 295-300 °C (subl.)(lit.)
alpha : 28 º (c=8, 6N HCl)
Dichte: 1.23
Brechungsindex: 28 ° (C=8, HCl)
storage temp. : Store at RT.
Löslichkeit: H2O: 25 mg/mL
Aggregatzustand: powder
pka: 2.29(at 25℃)
Farbe: White
PH: 5.5-6.5 (100g/l, H2O, 20℃)
Optische Aktivität: [α]20/D +27.0±0.5°, c = 5% in 5 M HCl
Wasserlöslichkeit: 85 g/L (20 ºC)
maximale Wellenlänge (λmax): λ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.1
Merck : 14,9909
BRN : 1721136
InChIKey: KZSNJWFQEVHDMF-BYPYZUCNSA-N
CAS Datenbank: 72-18-4(CAS DataBase Reference)
NIST chemische Informationen: Valine(72-18-4)
Sicherheit
Kennzeichnung gefährlicher: Xn
R-Sätze:: 40
S-Sätze:: 24/25-36-22
WGK Germany : 3
RTECS-Nr.: YV9361000
TSCA : Yes
HS Code : 29224995

L-Valin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S22:Staub nicht einatmen.
Beschreibung
Valine (abbreviated as Val or V) is an α-amino acid with the chemical formula HO2CCH(NH2)CH(CH3)2. L-Valine is one of 20 proteinogenic amino acids. Its codons are GUU, GUC, GUA, and GUG. This essential amino acid is classified as nonpolar. Human dietary sources are any proteinaceous foods such as meats, dairy products, soy products, beans and legumes.
Along with leucine and isoleucine, valine is a branched-chain amino acid. It is named after the plant valerian. In sickle-cell disease, valine substitutes for the hydrophilic amino acid glutamic acid in hemoglobin. Because valine is hydrophobic, the hemoglobin is prone to abnormal aggregation.
Chemische Eigenschaften
White or almost white, crystalline powder or colourless crystals, soluble in water, very slightly soluble in alcohol.
Verwenden
L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grai ns, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.
Verwenden
valine is an amino acid used as a skin-conditioning and odor-masking agent. It is more commonly used in hair care preparations than in skin care.
Definition
ChEBI: The L-enantiomer of valine.
Biosynthese
Valine is an essential amino acid, hence it must be ingested, usually as a component of proteins. It is synthesized in plants via several steps starting from pyruvic acid. The initial part of the pathway also leads to leucine. The intermediate α-ketoisovalerate undergoes reductive amination with glutamate. Enzymes involved in this biosynthesis include :
Acetolactate synthase
Acetohydroxy acid isomeroreductase
Dihydroxyacid dehydratase
Valine aminotransferase.
Sicherheitsprofil
Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Chemical Synthesis
Racemic valine can be synthesized by bromination of isovaleric acid followed by amination of the α-bromo derivative
HO2CCH2CH(CH3)2 + Br2 → HO2CCHBrCH(CH3)2 + HBr
HO2CCHBrCH(CH3)2 + 2 NH3 → HO2CCH(NH2)CH(CH3)2 + NH4Br
.
läuterung methode
Crystallise L-valine from water by addition of EtOH. It sublimes at 178-188o/0.03mm with 99.3% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Perrin J Chm Soc 3125 1958, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2368-23771961, Beilstein 4 IV 2659.]
Nomenclature
According to IUPAC, carbon atoms forming valine are numbered sequentially starting from 1 denoting the carboxyl carbon, whereas 4 and 4' denote the two terminal methyl carbons.
L-Valin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Glucose Hydantoin Isobutanol Glutaminsure DL-Valin Harnstoff Cyanwasserstoff Isobutyraldehyd Diammoniumcarbonat Isobutyronitril
Downstream Produkte
N-[(tert-Butoxy)carbonyl]-L-valin
L-Valin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 524)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95sales@capotchem.com China 19919 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32457 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012sales03@shyrchem.com CHINA 661 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122sales@fine-chemtech.com CHINA 892 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796ivan@atkchemical.com CHINA 24196 60
 
72-18-4(L-Valin)Verwandte Suche:
DL-Phenylalanin L-Prolin Arginin Lithiumbis(trimethylsilyl)amid Methyl-4-(4-aminophenyl)butyrat ALTRENOGEST phosphoric acid N,N-Dimethyl-phenylendiamin (p) 4-Aminobuttersure L-Valine methyl ester hydrochloride Glycin Folsure Valine N-[(tert-Butoxy)carbonyl]-L-valin DL-Valin Isovaleriansäure AMINO ACIDS L-Valin
L-Valine (High Purity ) 2,3-D2) L-Valine, Animal-Free L-VALINE BIOULTRA, >= 99.5% (NT) L-VALINE, REAGENT GRADE, >=98% (HPLC L-ValineUSP, 98.5-101.5% (Titration: anhydrous basis) L-Valine,99%e.e. (S)-(+)-VALINE (S)-ALPHA-AMINOISOVALERIC ACID VALINE, L- VALINE 2-AMINO-3-METHYLBUTANOIC ACID 2-AMINOISOVALERIC ACID H-VAL-OH H-L-VAL-OH L-2-AMINO-3-METHYLBUTANOIC ACID L-2-AMINO-3-METHYLBUTYRIC ACID L-2-AMINOISOVALERIC ACID L-A-AMINOISOVALERIC ACID L-ALPHA-AMINOISOVALERIANIC ACID L-VLA L-(+)-VALINE L-VALINE Valin (S)-α-Aminoisovaleric acid L-Valine, FCC Grade L-2-Amino-3-methylbutyric acid, FCC Grade L-Val-OH La-Amino-b-methylbutyric acid L-Valine FCC4/USP24 L-VALINE (USP/EP/JP) L-VALINE, MANUFACTURING GRADE L-VALINE 99% CELL CULTURE REAGENT L-VALINE 99-105% (USP EP JP) L-ValineForBiochemistry L-ValineForBiochemistry99+% L-ValineForBiochemistry-(S)-A-AminoisovalericAcid L-VALINE 99% FOR BIOCHEMISTRY L-Valine-D8, 15N L-VALINE,CRYSTAL L-VALINE,CRYSTAL,FCC VALINE,CRYSTAL,USP (2S)-2-amino-3-methyl-butanoic acid VALINE, L-(RG) (S)-a-Amino-b-methylbutyric acid L-Valine (9CI) (s)-2-amino-3-methylbutanoicacid (S)-2-Amino-3-methylbutansαure (s)-2-amino-3-methylbutyricacid (s)-alpha-amino-beta-methylbutyricacid 2-Amino-3-methylbutyric acid Butanoic acid, 2-amino-3-methyl- Butanoic acid, 2-amino-3-methyl-, (S)- l-(+)-alpha-Aminoisovaleric acid l-alpha-amino-beta-methylbutyricacid L-iso-C3H7CH(NH2)COOH L-α-Amino-isovaleriansαure L-Valine >99.5% L-VALINE extrapure CHR
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