Cholesterin
- CAS No.
- 57-88-5
- Chemical Name:
- Cholesterin
- Synonyms
- Cholestrol;CHO-HP;Cholest-5-en-3-ol;(3.beta.)-Cholest-5-en-3-ol;Lanol;CHOLESTERIN;SYNTHETIC CHOLESTEROL;CHOLESTEROL SIGMA GRADE;CHOLESTEROL HP;CHOLESTEROL XG
- CBNumber:
- CB00130348
- Molecular Formula:
- C27H46O
Lewis structure
- Molecular Weight:
- 386.66
- MDL Number:
- MFCD00003646
- MOL File:
- 57-88-5.mol
- MSDS File:
- SDS
Melting point | 148-150 °C |
---|---|
alpha | -36 º (c=2, dioxane) |
Boiling point | 360 °C |
Density | 1.06 |
refractive index | 1.5250 (estimate) |
Flash point | 250 °C |
storage temp. | -20°C |
solubility | H2O: 0.002 mg/mL |
pka | 15.03±0.70(Predicted) |
form | powder |
Specific Gravity | 1.067 |
color | white |
Odor | wh. or faintly yel. pearly granules or crystals, almost odorless |
Water Solubility | negligible |
Merck | 14,2201 |
BRN | 1915888 |
Dielectric constant | 2.9(Ambient) |
InChIKey | HVYWMOMLDIMFJA-DPAQBDIFSA-N |
LogP | 9.619 (est) |
FDA 21 CFR | 101.9 |
CAS DataBase Reference | 57-88-5(CAS DataBase Reference) |
EWG's Food Scores | 1 |
NCI Dictionary of Cancer Terms | cholesterol |
FDA UNII | 97C5T2UQ7J |
IARC | 3 (Vol. 31, Sup 7) 1987 |
NIST Chemistry Reference | Cholesterol(57-88-5) |
EPA Substance Registry System | Cholesterol (57-88-5) |
Cosmetics Info | Cholesterol |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372 |
Precautionary statements | P201-P261-P304+P340+P312-P305+P351+P338-P308+P313-P403+P233 |
Hazard Codes | Xn,Xi |
Risk Statements | 10-48/20/22-40-38-22-36/37/38-67-36/38-20-63 |
Safety Statements | 24/25-22-36/37-36-26 |
RIDADR | UN 1170 3/PG 3 |
WGK Germany | 1 |
RTECS | FZ8400000 |
TSCA | Yes |
HS Code | 2906 13 10 |
HazardClass | IRRITANT |
Toxicity | Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease. |
Cholesterin price More Price(83)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | NIST911C | Cholesterol NIST? SRM? 911c | 57-88-5 | 2g | $1710 | 2024-03-01 | Buy |
Sigma-Aldrich | 47127-U | Cholesterol solution certified reference material, 10?mg/mL in chloroform | 57-88-5 | 1mL | $56.9 | 2024-03-01 | Buy |
Sigma-Aldrich | 228111 | Cholesterol, Highly Purified - CAS 57-88-5 - Calbiochem Suitable for use in liposome preparations. | 57-88-5 | 5G | $69 | 2024-03-01 | Buy |
Sigma-Aldrich | 1131960 | Cholesterol United States Pharmacopeia (USP) Reference Standard | 57-88-5 | 125mg | $491 | 2024-03-01 | Buy |
Sigma-Aldrich | 1.03672 | Cholesterol from wool fat extrapure,powderedEMPROVE?ESSENTIALPhEur,BP,NF,JP | 57-88-5 | 5kg | $3212 | 2024-03-01 | Buy |
Cholesterin Chemical Properties,Uses,Production
Description
As cholesterin seems to be a constituent of most if not all cells, it may be assumed that it is of some importance, even though the quantity is generally small, yet to this time its real purpose has remained practically unknown.
Occurrence
Cholesterin is widely found and distributed in animal bodies, and is especially most abundant in the brain and nerve tissue. It also has high content in the kidney, spleen, skin, liver and bile. The solubility of cholesterin is similar to that of the fat which is insoluble in water, but easily soluble in ether, chloroform and some other solvents.
Biological Functions
The main physiological function of cholesterin participating in forming cell membranes, myelin, brain, and can be further converted to bile acids and steroid hormones. There are two major lipoproteins which are involved in cholesterin transport: the low density lipoprotein (LDL) and high density lipoprotein (HDL). The former can transport cholesterol from the liver to the cells of whole body tissues, while the later one transports cholesterol from tissue cells back into the liver.
Chemical Reactivity
Chemically, cholesterin is one of the most inert of the body constituents, and it seems improbable that it plays any part in metabolic processes, for which reason there have been those who have been content to consider cholesterin as merely a by-product in cell metabolism, which was present in the cells in recognizable quantities, chiefly because its resistance to alteration made its removal slow.
Side effects
The cholesterol level in the blood can reflect the overall metabolism condition of cholesterol. The total cholesterol content in the blood plasma of normal adult of empty stomach is about 2.83~5.17mmol/L. Abnormal cholesterol metabolism could easily lead to deposition of cholesterol in the blood vessel wall, forming atherosclerosis, causing coronary heart disease and stroke.
Physiological effects
Cholesterin is closely related to the body tissues, bile acids and hormones. It is an indispensable substance of animal tissue cells, which is not only involved in the formation of cell membranes, but also as the precursor for the synthesis of bile acids, steroid hormones and vitamin D3.
Cholesterin Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
Chengdu Yuanda Chemical Co., Ltd | 28-85356300 +8618980937689 | sales@ydachem.com | CHINA | 94 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
Shanghai QiXin New Materials Technology Co.,Ltd | +8615116235351 | derrickguo@sh-qixin.cn | China | 16 | 58 |
Pharmaceuticals Group Corp., Ltd. | +8613004379774 | wu@jiaerke.com | China | 33 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 | sales@kindchem.cn | China | 1227 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | ada@sh-teruiop.com | China | 893 | 58 |
Wuhan Han Sheng New Material Technology Co.,Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2118 | 58 |
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View Lastest Price from Cholesterin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd