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N,N-Dimethylformamide dimethyl acetal

Chemical Name:
N,N-Dimethylformamide dimethyl acetal
DMF-DMA;1,1-dimethoxy-n,n-dimethyl-methanamin;DMF-DIMETHYLACETAL;1,1-DIMETHOXYTRIMETHYLAMINE;(Dimethylamino)dimethoxymethane;DIMETHYLFORMAMIDEDIMETHYLACETAL;N-(Dimethoxymethyl)dimethylamine;Dimethoxy-N,N-dimethylmethanamine;N,N-Dimethylformamide dimethyl acetal, 95% (1,1-Dimethoxytrimethylamine);METHYL-8
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Modify Date:2022-12-21 16:56:50

N,N-Dimethylformamide dimethyl acetal Properties

Melting point -85°C
Boiling point 102-103 °C/720 mmHg (lit.)
Density 0.897 g/mL at 25 °C (lit.)
vapor pressure 34.5hPa at 20℃
refractive index n20/D 1.396(lit.)
Flash point 45 °F
storage temp. Store below +30°C.
solubility Miscible with most organic solvents.
pka 5.00±0.50(Predicted)
form Solid
color White to off-white
PH 7 (H2O)
explosive limit 1.3-17.7%(V)
Water Solubility hydrolysis
Sensitive Moisture Sensitive
BRN 506020
Exposure limits ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3)
CAS DataBase Reference 4637-24-5(CAS DataBase Reference)
NIST Chemistry Reference Methanamine, 1,1-dimethoxy-N,N-dimethyl-(4637-24-5)
EPA Substance Registry System Methanamine, 1,1-dimethoxy-N,N-dimethyl- (4637-24-5)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word  Danger
Hazard statements  H225-H317-H318-H332
Precautionary statements  P210-P280-P302+P352-P304+P340+P312-P305+P351+P338+P310
Hazard Codes  F,Xn,Xi
Risk Statements  11-22-36/37/38-36/38-20-20/21/22-10-52
Safety Statements  16-26-36/37-36/37/39-33-29-7/9
RIDADR  UN 3271 3/PG 2
WGK Germany  1
Autoignition Temperature 155 °C
HazardClass  3
PackingGroup  II
HS Code  29225000
Toxicity LD50 orally in Rabbit: > 5000 mg/kg
NFPA 704
3 1

N,N-Dimethylformamide dimethyl acetal price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.03068 N,N-Dimethylformamide dimethyl acetal for synthesis 4637-24-5 1mL $32.3 2023-01-07 Buy
Sigma-Aldrich 8.03068 N,N-Dimethylformamide dimethyl acetal for synthesis 4637-24-5 25mL $61.3 2023-01-07 Buy
Sigma-Aldrich 8.03068 N,N-Dimethylformamide dimethyl acetal for synthesis 4637-24-5 100mL $154 2023-01-07 Buy
Sigma-Aldrich 8.03068 N,N-Dimethylformamide dimethyl acetal for synthesis 4637-24-5 500mL $377 2023-01-07 Buy
Sigma-Aldrich 140732 N,N-Dimethylformamide dimethyl acetal technical grade, 94% 4637-24-5 25ml $62.1 2023-01-07 Buy
Product number Packaging Price Buy
8.03068 1mL $32.3 Buy
8.03068 25mL $61.3 Buy
8.03068 100mL $154 Buy
8.03068 500mL $377 Buy
140732 25ml $62.1 Buy

N,N-Dimethylformamide dimethyl acetal Chemical Properties,Uses,Production

Chemical Properties

clear colourless liquid


Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.


1,1-Dimethoxy-N,N-dimethylmethanamine is used as a reagent in the formation of pyridine derivatives that exhibit inhibition against PI3 kinase p110α enzymes.


N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.


ChEBI: An acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applica ions

General Description

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.

Flammability and Explosibility


N,N-Dimethylformamide dimethyl acetal Preparation Products And Raw materials

Raw materials

Preparation Products


Global( 631)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Sinoda Biological Technology Co., Ltd
+8613401983379 CHINA 74 58
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571-85586718 +8613336195806 China 29801 60
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+86-0371-55170693 +86-19937530512 China 21975 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714 China 9364 55
21-51619050 China 31323 60
career henan chemical co
+86-0371-86658258 China 29922 58
Klong Industrial Co., Ltd
0086-519-68231162 CHINA 131 58

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View Lastest Price from N,N-Dimethylformamide dimethyl acetal manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N-Dimethylformamide dimethyl acetal pictures 2023-01-31 N,N-Dimethylformamide dimethyl acetal
US $100.00 / KG 1KG 99% 5000kg/week Hebei Mojin Biotechnology Co., Ltd
N,N-Dimethylformamide dimethyl acetal pictures 2023-01-31 N,N-Dimethylformamide dimethyl acetal
US $9.90-9.90 / g 5g 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customiz 100kg Wuhan Biocar Pharmacy Co., Ltd.
N,N-Dimethylformamide dimethyl acetal pictures 2021-12-03 N,N-Dimethylformamide dimethyl acetal
US $10.00 / KG 1KG 99% 5tons Hebei Guanlang Biotechnology Co., Ltd.
Dimethoxy(dimethylamino)methane N,N-Dimethylfirmanmidedimethylacetal N,N-Dimethylformamide dimethyl acetal, ca 97% Methanamine, 1,1-dimethoxy-N,N-dimethyl- esterate m n,n-dimethylformamide dimethyl acetal solution N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL (DMF-DMA) 1,1-Dimethoxytrimethylamin N,N -DIMETHYL FORMAMIDE DIMETHYL ACETYL N,N'-Dimethylformanimide dimethyl acetal N,N-Dimethylformamide Dimethyl Acetal [for Esterification] (0.5ml*10) (Dimethylamino)formaldehyde Dimethoxy-N,N-dimethylmethylamine N,N-Dimethylformamide dimethyl acetal ,95% (Dimethylamino)formaldehyde dimethyl acetal Dimethyl(dimethoxymethyl)amine Dimethylaminomethanal dimethyl acetal N,N-Dimethyl-α,α-dimethoxymethanamine N,N-Dimethylformamide Dimethyl Acetal [for Esterification] 1,1-Dimethoxy-N,N-dimethylmethylamine, 1,1-Dimethoxytrimethylamine Trimethylamine, 1,1-dimethoxy- N,N-DIMETHYLDIMETHOXYMETHYLAMINE N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL N-DIMETHOXYMETHYL-N,N-DIMETHYLAMINE AURORA KA-683 METHYL-8 REAGENT METHYL-8(R) REAGENT METHYL-8 DMFDMA (DMFA) 1,1-DIMETHOXY-N,N-DIMETHYL METHANAMINE 1,1-DIMETHOXY-N,N-DIMETHYLMETHYLAMINE dimethylformamidediemthylacetal N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL, 9 4% N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL, D ERIVATIZATION GRADE DMFDMA [N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL] DmfDmaAcetal N,N-Dimethylformamide dimethyl acetal, 97+% N,N-dimethyl for mamide dimethyl acctel DMFDMA [N N-DiMethylforMaMide diMethyl acetal] N,N-DiMethylforMaMide diMethylacetal(DMFDA) N,N-DiMethylforMaMide diMethyl acetal, ca. 97% 100GR N,N-DiMethylforMaMide diMethyl acetal, ca. 97% 25GR N,N-DiMethylforMaMide diMethyl acetal, ca. 97% 500GR N,N-Dimethylformamide dimethyl acetal, ca. 97% N,N-Dimethylformamide Dimethyl Acetal£¨DMADMF£ N,N-DiMethylforMaMide diMethyl acetal, ca. 97%, AcroSeal N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL FO (Dimethoxymethyl)dimethylamine, 1,1-Dimethoxy-N,N-dimethylmethylamine N,N-two DMFtwoMethylal N,N-DiMethylforMaMide diMethyl acetal technical grade, 94% DiMethylfirManMidediMethylacetal(DMFDMA) N,N-Dimethylformamide dimethyl acetal N,N-Dimethylformamide dim Leflunomide Impurity 5 formamide dimethyL N,N-Dimethylformamide Dimethyl Acetal [for Esterification]> N,N-Dimethylformamide Dimethyl Acetal >