플루바스타틴나트륨염
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플루바스타틴나트륨염 속성
- 녹는점
- 194-197°C
- 저장 조건
- 2-8°C
- 용해도
- H2O: ≥9mg/mL
- 물리적 상태
- 가루
- 색상
- 흰색에서 황갈색까지
- Merck
- 14,4218
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 증류수에 용해된 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.
- InChIKey
- ZGGHKIMDNBDHJB-RPQBTBOMSA-M
- CAS 데이터베이스
- 93957-55-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
---|---|---|---|
RTECS 번호 | MJ9675050 | ||
HS 번호 | 2933995300 |
플루바스타틴나트륨염 C화학적 특성, 용도, 생산
개요
Fluvastatin sodium is the fourth HMG-CoA reductase inhibitor to reach the market as a dietary adjunct for lowing total and low-density lipoprotein (LDL) cholesterol. Fluvastatin sodium is the first totally synthetic inhibitor of its class and has more potent effects on reducing serum total and LDL cholesterol and serum triglyceride levels than compactin or lovastatin. Moreover, fluvastatin exhibits a unique set of pharmacological properties including a biopharmaceutical profile most consistent with hepatoselectivity. It has been reported to be well tolerated and to exhibit a safety profile superior to other agents of its class. The main mechanism by which HMG-CoA reductase inhibitors lower plasma cholesterol has been suggested to be up-regulation of hepatocellular LDL-receptor expression and enhancement of receptor-mediated clearance and catabolism of LDL cholesterol.화학적 성질
Yellow Powder용도
Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.일반 설명
Fluvastatin sodium is a lipid-lowering drug that belongs to the group of compounds known as statins. It acts by inhibiting the enzyme HMG-CoA reductase that plays a key role in the cholesterol production. It is generally used to reduce plasma cholesterol levels and prevent cardiovascular disease.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
생물학적 활성
Orally active, potent and competitive HMG-CoA reductase inhibitor (IC 50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC 50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo .플루바스타틴나트륨염 준비 용품 및 원자재
원자재
트리에틸보란
아크롤레인
이소프로필아닐린
3-클로로페록시벤조산
플루오르벤젠
Boric acid esters
메틸 아세토아세테이트
나트륨 붕소수화물
알릴아민
트리페닐포스핀
부틸디페닐클로로실란
푸란
수산화나트륨
클로로아세틸 클로라이드
준비 용품
플루바스타틴나트륨염 공급 업체
글로벌( 371)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 |
sales@ichemie.com | China | 990 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
플루바스타틴나트륨염 관련 검색:
1-히드록시에틸리덴-1,1-디포스포닌산 메틸 페닐 실로산과 실리콘 포름산나트륨 아세트산 나트륨 디클로페낙 나트륨 글루콘산나트륨 수산화나트륨 중탄산나트륨(중조) 벤조 산, 나트륨 염 탄산나트륨(경회) 염화나트륨 메틸에틸케톤
Chlorodimethylphenylsilane
(2-Methoxyethyl)benzene
ATORVASTATIN SODIUM
Pravastatin sodium
Fluvastatin
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT