2-오소-1-피리딘아세트아마이드;피라세탐

2-오소-1-피리딘아세트아마이드;피라세탐 속성

2-오소-1-피리딘아세트아마이드;피라세탐 MSDS

Piracetam

2-오소-1-피리딘아세트아마이드;피라세탐 C화학적 특성, 용도, 생산

개요

Piracetam is a nootropic agent with an indication as adjunctive treatment for myoclonus of cortical origin, as well as tardive dyskinesia. However, piracetam is not approved by the FDA for any medical use in the USA. Piracetam should not be prescribed in patients with Huntington disease, those with serious kidney problems, or patients who have experienced a brain haemorrhage. Bleeding problems are a further caution to be taken into account. Although there is little evidence for piracetam’s efficacy in terms of long- term benefits for the treatment of mild cognitive impairments, recent studies showed that it is effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins. With regard to piracetam’s behavioural profile, its beneficial effects on lowering depression and anxiety appear to be higher than its positive effects on memory.

화학적 성질

White crystalline powder. Odorless, slightly bitter taste. Soluble in water, slightly soluble in ethanol, almost insoluble in ether.

용도

Piracetam has been used to study crystal structure and physicochemical properties of six co-crystals of piracetam. It has also been used to study its in vitro antioxidant properties.

용도

Piracetam is most commonly used for breath-holding attacks, seizure disorder (epilepsy), antinauseant, dizziness (vertigo), a learning disorder marked by difficulty reading (dyslexia), nootropic, cortical myoclonus, and a movement disorder often caused by antipsychotic drugs (tardive dyskinesia).

정의

ChEBI: Piracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. It is a compound suggested to be both a nootropic and a neuroprotective agent.

제조 방법

Prepared by condensing 2-pyrrolidinone with ethyl chloroacetate in the presence of a metal hydride and then converting the ester into an amide with ammonia.

생물학적 활성

Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux; potentiates Na + influx through AMPA receptors. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.

Safety Profile

Mildly toxic by ingestion. Whenheated to decomposition it emits toxic fumes of NOx.

신진 대사

The plasma half life of piracetam is approximately 5 hours following oral or intravenous administration. The half life in the cerebrospinal fluid was 8.5 hours. The apparent total body clearance is 80-90 mL/min.

Purification Methods

This typical nootropic (Alzheimer) drug modulates Na flux in AMPA receptors and is purified by recrystallisation from isoPrOH. [Gouilaev & Senning Brain Research Rev 19 180 1994.]

2-오소-1-피리딘아세트아마이드;피라세탐 준비 용품 및 원자재

원자재

준비 용품

2-오소-1-피리딘아세트아마이드;피라세탐 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Xi'an ZB Biotech Co.,Ltd	+8618591943808	sales01@xazbbio.com	China	816	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9339	58
APOLLO HEALTHCARE RESOURCES	+6596580999	sales@apollo-healthcare.com.sg	Singapore	400	58
Wuhan senwayer century chemical Co.,Ltd	+undefined-27-86652399 +undefined13627115097	market02@senwayer.com	China	874	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	991	58
Wuhan Quanjinci New Material Co.,Ltd.	+8615271838296	kyra@quanjinci.com	China	1532	58
Shanghai Affida new material science and technology center	+undefined15081010295	2691956269@qq.com	China	359	58
Dorne Chemical Technology co. LTD	+86-13583358881 +86-18560316533	Ethan@dornechem.com	China	294	58
Hebei Lingding Biotechnology Co., Ltd.	+86-18031140164 +86-19933155420	erin@hbldbiotech.com	China	878	58

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